A Study of Food Effect on Tersolisib (LY4064809) in Healthy Participants

• Are healthy as determined by no clinically significant findings from medical history, physical examination, 12-lead electrocardiogram (ECG), vital sign measurements, or clinical laboratory evaluations.
• Normal blood pressure and pulse rate.
• Body mass index (BMI) within the range 18.0 to 32.0 kilograms per square meter (kg/m²), inclusive.
• Participants assigned male at birth (AMAB) or participants assigned female at birth (AFAB) who are individuals not of childbearing potential (INOCBP).

Exclusion Criteria:

• History or presence of any of the following conditions, deemed clinically significant by the investigator (or designee):

  • Metabolic disease, including congenital non-hemolytic hyperbilirubinemia, for example, Gilbert syndrome
  • Biliary disease, including cholecystectomy
  • Gastrointestinal (GI) disease
  • Hematological disease
  • Neurological disease
  • Significant history of, or presence of liver disease, including abnormal liver function tests above 1.25 times the upper limit of normal range per the laboratory's reference ranges at screening or admission, or
  • Clinically significant, active cardiovascular disease or history of myocardial infarction or significant cardiovascular disease.
• History of a major surgical procedure within 30 days prior to screening.
• Known allergies to tersolisib or related compounds.