ClinicalTrials.gg
Not yet recruitingNCT07657221Updated Jun 18, 2026

Impact of Risk Feedback on Behavioral Trajectories

An interventional study of PHEN feedback and PHEN+GENE Feedback in Healthy and Alcohol Consumption, sponsored by University of Southern California. Not yet recruiting at 1 site in United States. Open to participants aged 17 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-18.

Sponsored by University of Southern California · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
450
Allocation
Randomized
Ages
17 Years to 25 Years
Sex
All
01

Study summary

The goal of this study is to examine the effects of providing personalized information about behavioral, physical, and genetic factors that are associated with elevations in risk for some health problems. The main research question is: can we affect young adult behaviors through communication about these health-related risks? Participants will be asked to complete an in-person baseline session where they provide a DNA sample, complete online surveys, and do a brief interview. They will then receive one of several brief online information sessions and be followed in online surveys approximately every 3 months over the next 2 years.

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Conditions studied

  • Healthy
  • Alcohol Consumption

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03

In context

Alcohol Drinking

701 studies on the registry are indexed under Alcohol Drinking; 133 are open to participants now.

This study's planned enrollment of 450 is above the median of 122 across 607 interventional studies indexed under Alcohol Drinking.

Browse Alcohol Drinking studies →

Lead sponsor

University of Southern California is the lead sponsor of 791 studies on the registry; 136 are open to participants now.

Of its 70 completed or terminated interventional studies of FDA-regulated products, 32 (46%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
17 Years to 25 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • USC student of Chinese, Japanese, Korean, or Vietnamese heritage

Exclusion criteria

Exclusion Criteria:

  • not a USC student, not 17-25 years old, not of Chinese, Japanese, Korean, or Vietnamese heritage
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Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
450 participants (estimated)

Study arms

  • Experimental
    PHEN

    provided phenotypic feedback

    Behavioral: PHEN feedback

  • Experimental
    GENE

    provides genotypic feedback

    Behavioral: PHEN feedback · Genetic: PHEN+GENE Feedback

  • Placebo comparator
    CONTROL

    provided a control feedback

    Other: Control

Interventions

  • BehavioralPHEN feedback

    Feedback on alcohol response (phenotype)

  • GeneticPHEN+GENE Feedback

    Feedback on both phenotype and genotype (PHEN+GENE)

  • OtherControl

    Feedback that serves as control

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What researchers measure

Primary outcomes

  1. Drinking frequency

    Number of days consumed alcohol

    Time frame: up to 2 years post-intervention

  2. Average alcohol quantity

    Average amount of alcohol consumed on drinking days

    Time frame: up to 2 years post-intervention

Secondary outcomes

  1. Amount of alcohol consumed

    Total number of drinks consumed

    Time frame: up to 2 years post-intervention

  2. Maximum daily alcohol

    Highest number of drinks consumed on one day

    Time frame: up to 2 years post-intervention

  3. Use of flush cures

    Proportion of drinking days used flush cures

    Time frame: up to 2 years post-intervention

  4. Use of drinking behavioral strategies

    Proportion of drinking days used behavioral strategies

    Time frame: up to 2 years post-intervention

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Study locations

1 site
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References and documents

Individual participant data

Plan to share: Yes — For participants who agree to have their data included, de-identified participant data will be uploaded to the National Institute of Mental Health Data Archive (NDA).

Supporting information: Study protocol, Statistical analysis plan, Informed consent form

Time frame: Data will be available no later than 2 years post-study completion and will be available indefinitely.

Access criteria: Access will be made in accordance with NDA regulations.

No publications or documents are linked to this record.

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Aug 2026; primary completion for Feb 2029, 30 months later.

Of 328 non-industry interventional studies with no phase under Alcohol Drinking, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 45. This study's planned 30 months is above that.

Counting every sponsor, half of 336 studies reached it within 24 months; a quarter within 10 and three quarters within 45.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 9, 2026
First posted
Jun 18, 2026
StartEst.
Aug 18, 2026
Primary completionEst.
Feb 28, 2029
CompletionEst.
Aug 31, 2030
Last update
Jun 18, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 18, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07657221
Responsible party
Susan Luczak (Professor (Research), University of Southern California) — Principal investigator
First posted
Jun 18, 2026
Start date
Aug 18, 2026 (estimated)
Primary completion
Feb 28, 2029 (estimated)
Completion
Aug 31, 2030 (estimated)
Last update
Jun 18, 2026

Study contacts

Susan Luczak, PhD
Contact
luczak@usc.edu
2137402203
Susan Luczak, PhD
principal investigator · University of Southern California

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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