CClinicalTrials.gg
CompletedNCT07653126LUNET-2Updated Jun 17, 2026

A Study of Peptide Receptor Radionuclide Therapy (PRRT) Use in Neuroendocrine Tumor (NET) Patients in Germany

An observational study in Gastro-enteropancreatic Neuroendocrine Tumor, sponsored by Novartis Pharmaceuticals. Completed at 7 sites in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-17.

Sponsored by Novartis Pharmaceuticals · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
117
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study was to assess patient characteristics and treatment patterns of gastro-enteropancreatic neuroendocrine tumor (GEP-NET) patients who received PRRT in German routine care.

02

Conditions studied

  • Gastro-enteropancreatic Neuroendocrine Tumor

Keywords

  • Neuroendocrine Tumors
  • Gastroenteropancreatic Neuroendocrine Tumors
  • GEP-NET
  • Peptide Receptor Radionuclide Therapy
  • PRRT
  • Lutetium-177
  • 177Lu-DOTATATE
  • Real World
  • Germany
03

In context

Gastro-enteropancreatic neuroendocrine tumor

32 studies on the registry are indexed under Gastro-enteropancreatic neuroendocrine tumor; 12 are open to participants now.

Browse Gastro-enteropancreatic neuroendocrine tumor studies →

Lead sponsor

Novartis Pharmaceuticals is the lead sponsor of 2,673 studies on the registry; 228 are open to participants now.

Of its 576 completed or terminated interventional studies of FDA-regulated products, 431 (75%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult GEP-NET patients in Germany who received their first cycle of primary PRRT between 01 July 2020 and 30 June 2021.

Inclusion criteria

  • Patients with a confirmed diagnosis of GEP-NET (any localization of the primary tumor including cancer of unknown primary origin [CUP], any Grade).
  • Patients with a first cycle of primary PRRT of home-brew 177Lu-DOTATATE/DOTATOC or Lutathera® between 01 July 2020 and 30 June 2021.

Exclusion criteria

Exclusion criteria:

  • Received a combination of PRRT with chemotherapy.
  • Received a combination of PRRT with a radionuclide other than lutetium-177 (e.g., yttrium-90).
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
117 participants (actual)
Patient registry
No

Groups and cohorts

  • PRRT Cohort

    Adult GEP-NET patients who received PRRT in German routine care.

06

What researchers measure

Primary outcomes

  1. Baseline Demographics

    Time frame: Baseline

  2. Number of Patients by Tumor Status

    Time frame: Baseline

  3. Duration Between Initial Diagnosis and Initiation of Primary PRRT

    Time frame: Baseline

  4. Number of Patients by PRRT Line of Therapy

    Time frame: Approximately 1 year

  5. Number of Patients by Type of PRRT Received

    Time frame: Approximately 1 year

  6. PRRT Dosage

    Time frame: Approximately 1 year

  7. Number of Patients by Treatment Interval

    Time frame: Approximately 1 year

  8. Number of Patients by Co-medication

    Time frame: Approximately 1 year

07

Study locations

7 sites
  • Novartis Investigative Site
    Essen, Germany
  • Novartis Investigative Site
    Heidelberg, Germany
  • Novartis Investigative Site
    München, Germany
  • Novartis Investigative Site
    Rostock, Germany
  • Novartis Investigative Site
    Stuttgart, Germany
  • Novartis Investigative Site
    Tübingen, Germany
  • Novartis Investigative Site
    Würzburg, Germany
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07653126
Lead sponsor
Novartis Pharmaceuticals
Responsible party
Sponsor
First posted
Jun 17, 2026
Start date
Apr 3, 2023
Primary completion
Sep 29, 2023
Completion
Sep 29, 2023
Last update
Jun 17, 2026

Study contacts

Novartis Pharmaceuticals
study director · Novartis Pharmaceuticals
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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