CClinicalTrials.gg
RecruitingNCT07650877Updated Jun 16, 2026

Comparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block

An interventional study of Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block in Pain, Postoperative, Multimodal Analgesia and Rhomboid Intercostal Block, sponsored by Ankara City Hospital Bilkent. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-06-16.

Sponsored by Ankara City Hospital Bilkent · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Jun 2026; still recruiting 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
18 Years to 75 Years
Sex
All
01

Study summary

Video-assisted thoracic surgery (VATS) is widely performed for the management of various thoracic pathologies and is generally associated with reduced surgical trauma compared with open thoracotomy. Nevertheless, patients may still experience considerable postoperative pain, which can adversely affect respiratory function, mobilization, and recovery. Various regional analgesic techniques have been incorporated into multimodal pain management strategies for VATS, including thoracic paravertebral block (TPVB), erector spinae plane block (ESPB), intercostal nerve block, serratus anterior plane block (SAPB), rhomboid intercostal block (RIB), and serratus posterior superior intercostal plane block (SPSIPB). Among these approaches, ultrasound-guided TPVB has traditionally been regarded as a reference regional analgesic technique. More recently, interfascial plane blocks have gained increasing attention because of their technical simplicity and favorable safety profile. RIB and SPSIPB are two novel interfascial plane blocks that may provide effective postoperative analgesia following thoracic surgery. The present study aims to compare the analgesic efficacy of RIB and SPSIPB in patients undergoing VATS and to evaluate their impact on postoperative pain outcomes.

02

Conditions studied

  • Pain, Postoperative
  • Multimodal Analgesia
  • Rhomboid Intercostal Block
  • Serratus Posterior Superior Intercostal Plane Block
  • Thoracic Surgery, Video-Assisted

Browse trials for

03

In context

Pain, Postoperative

5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.

This study's planned enrollment of 90 is above the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Ankara City Hospital Bilkent is the lead sponsor of 424 studies on the registry; 105 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients undergoing elective VATS
  • Patients aged 18-75 years
  • Patients with ASA (American Society of Anesthesiologists) class I-III
  • Patients who have given informed consent

Exclusion criteria

Exclusion Criteria:

  • Patients allergic to local anesthetics
  • Patients with bleeding disorders or those undergoing anticoagulant therapy
  • Pregnant and breastfeeding women
  • Patients with impaired consciousness, inability to communicate, or mental/cognitive impairment
  • Patients who refuse block application
  • Patients with infection in the area where the block will be applied
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
90 participants (estimated)

Study arms

  • Active comparator
    Rhomboid Intercostal Block

    For patients scheduled to receive a Rhomboid Intercostal Block (RIB), after sonographic identification of the relevant anatomical structures, the block needle is advanced using an in-plane ultrasound-guided technique beneath the rhomboid muscle until contact with the rib is achieved. Following hydrodissection with 2 mL of normal saline to confirm correct needle placement, 30 mL of 0.25% bupivacaine is injected into the interfascial plane.

    Drug: Rhomboid Intercostal Block

  • Active comparator
    Serratus Posterior Superior Intercostal Plane Block

    For patients scheduled to receive a Serratus Posterior Superior Intercostal Plane Block (SPSIPB), after sonographic identification of the relevant anatomical structures, the block needle is advanced using an in-plane ultrasound-guided technique beneath the serratus posterior superior muscle until contact with the rib is achieved. Following hydrodissection with 2 mL of normal saline to confirm correct needle placement, 30 mL of 0.25% bupivacaine is injected into the interfascial plane.

    Drug: Serratus Posterior Superior Intercostal Plane Block

Interventions

  • DrugRhomboid Intercostal Block

    Rhomboid intercostal block will be applied to the patients under real-time ultrasound guidance.

  • DrugSerratus Posterior Superior Intercostal Plane Block

    Serratus posterior superior intercostal plane block will be applied to the patients under real-time ultrasound guidance.

06

What researchers measure

Primary outcomes

  1. Surgical Pain Scores

    Surgical pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0mm (no pain) to 100mm (worst pain). Pain assessment will be done at 1st, 6th, 12th, and 24th hours after surgery.

    Time frame: 24 hours after surgery

Secondary outcomes

  1. Shoulder Pain Scores

    Shoulder pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0mm (no pain) to 100mm (worst pain). Pain assessment will be done at 1st, 6th, 12th, and 24th hours after surgery.

    Time frame: 24 hours after surgery

  2. Intraoperative remifentanil consumption

    The amount of remifentanil that patients need to maintain anesthesia during the intraoperative period will be recorded.

    Time frame: During the intraoperative period

07

Study locations

1 of 1 sites recruiting
  • Ankara City Hospital
    Çankaya, Ankara 06290, Turkey (Türkiye)
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07650877
Lead sponsor
Ankara City Hospital Bilkent
Responsible party
Nilgün Zengin (Principal İnvestigator, Ankara City Hospital Bilkent) — Principal investigator
First posted
Jun 16, 2026
Start date
Jun 15, 2026
Primary completion
Nov 20, 2026 (estimated)
Completion
Nov 30, 2026 (estimated)
Last update
Jun 16, 2026

Study contacts

Emine Nilgün Zengin, Associate Professor
Contact
nilbavullu@gmail.com
00905063370548
Hülya Yiğit, Associate Professor
Contact
yigitozay@hotmail.com
00905054853939

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion