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Active, not recruitingNCT07649382Updated Aug 5, 2026

A Novel Strategy for Endoscopic Dual-instrument Retrieval of Upper GI Foreign Body

An observational study in Foreign Body Ingestion, sponsored by Shanghai Zhongshan Hospital. Active, not recruiting at 1 site in China. Per ClinicalTrials.gov, last updated 2026-08-05.

Sponsored by Shanghai Zhongshan Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
10
Sex
All
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Study summary

We describe a single-center, retrospective case series (n = 10) for the utilization of dual instruments to extract foreign body at physiological narrowing. Foreign bodies that failed to remove with a single instrument or located in physiological narrowing into the duodenal bulb or descending duodenum were considered appropriate for this technique. Informed consent was obtained from all patients before the procedure.

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Conditions studied

  • Foreign Body Ingestion

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Keywords

  • foreign body
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In context

Foreign Bodies

29 studies on the registry are indexed under Foreign Bodies; 8 are open to participants now.

This study's enrollment of 10 is below the median of 100 across 19 observational studies indexed under Foreign Bodies.

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Lead sponsor

Shanghai Zhongshan Hospital is the lead sponsor of 652 studies on the registry; 291 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

In this study, we retrospectively examined the records of 10 patients who underwent endoscopic foreign body extraction at Zhongshan Hospital, Fudan University between January 2018 and January 2026. All patients initially presented to the emergency department and underwent an initial single-instrument endoscopic retrieval attempt. When single-instrument retrieval was unsuccessful or unstable, a dual-instrument endoscopic retrieval technique was subsequently applied. All procedures were performed by a single experienced therapeutic endoscopist.

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Inclusion criteria

-Consecutive patients who underwent dual-instrument endoscopic retrieval for upper gastrointestinal foreign bodies at our center during the study period.

Exclusion criteria

Exclusion Criteria:

-Patients with incomplete clinical or procedural records. Patients lost to follow-up immediately after the procedure.

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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
10 participants (actual)
Patient registry
No

Groups and cohorts

  • dual-instrument
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What researchers measure

Primary outcomes

  1. Successful Endoscopic Foreign Body Removal Rate

    Percentage of patients in whom the foreign body is completely removed using the dual-instrument endoscopic retrieval technique without the need for surgical intervention. Success will be assessed by direct endoscopic visualization and procedural records.

    Time frame: 1 day

Secondary outcomes

  1. Procedure-Related Adverse Event Rate

    Percentage of patients experiencing procedure-related adverse events, including mucosal injury, bleeding, perforation, aspiration, or infection. Adverse events will be assessed based on endoscopic findings, clinical evaluation, and post-procedural medical records.

    Time frame: 1 week

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Study locations

1 site
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References and documents

Publications

  • 1. Yu S, Wang X, Chen X. Removal of giant spherical foreign body in the esophagus by double-forceps endoscope and double balloon. J Int Med Res. 2020;48(8):0300060520941332. doi:10.1177/0300060520941332 2. Birk M, Bauerfeind P, Deprez P, et al. Removal of foreign bodies in the upper gastrointestinal tract in adults: European society of gastrointestinal endoscopy (ESGE) clinical guideline. Endoscopy. 2016;48(05):489-496. doi:10.1055/s-0042-100456 3. Emara M, Darwiesh E, Refaey M, Galal S. Endoscopic removal of foreign bodies from the upper gastrointestinal tract: 5-year experience. CEG. Published online July 2014:249. doi:10.2147/CEG.S63274

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 5, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07649382
Responsible party
Quan-Lin Li (Professor, Shanghai Zhongshan Hospital) — Principal investigator
First posted
Jun 16, 2026
Start date
Oct 1, 2025
Primary completion
Oct 1, 2026 (estimated)
Completion
Dec 1, 2026 (estimated)
Last update
Aug 5, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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