A Phase 4 interventional study of Technology-assisted inverse kinematic alignment TKA and Manual-instrumented gap balancing alignment TKA in Osteo Arthritis of the Knee and Obesity & Overweight, sponsored by Jacob M. Elkins. Not yet recruiting. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2026-06-12.
Sponsored by Jacob M. Elkins · Phase 4, Interventional, and Treatment
The purpose of this research study is to compare two different methods used to align the knee during a total knee arthroplasty (TKA): technology-assisted inverse kinematic alignment, and manual-instrumented gap balancing alignment. The first technique uses robotic or computer-assisted technology to help the surgeon place the knee implant based on the patient's individual anatomy, whereas the manual technique uses standard surgical instruments and manual methods to position and balance the knee implant during surgery. The main difference is that one approach uses robotic or computer assistance to help guide implant positioning, while the other uses traditional instruments and manual surgical techniques. Both methods are commonly used and are considered standard care. The goal of this study is to understand whether one method results in better knee motion, function, and recovery after surgery in patients with higher body weight.
6,296 studies on the registry are indexed under Obesity; 1,692 are open to participants now.
This study's planned enrollment of 80 is close to the median of 78 across 4,878 interventional studies indexed under Obesity.
Browse Obesity studies →Jacob M. Elkins is the lead sponsor of 3 studies on the registry; 1 is open to participants now.
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Exclusion Criteria:
Procedure: Technology-assisted inverse kinematic alignment TKA
Procedure: Manual-instrumented gap balancing alignment TKA
This technique uses robotic or computer-assisted technology to help the surgeon place the knee implant based on the patient's individual anatomy.
This manual technique uses standard surgical instruments and manual methods to position and balance the knee implant during surgery.
Range of motion
Time frame: From enrollment to the end of follow-up at 1 year after intervention.
No study locations are listed for this record.
Plan to share: Yes — This study will be using the OpenCap motion capture system to collect gait data of participants. These recordings are stored in the OpenCap server and thus are shared with the OpenCap developers. Participants can request the removal of these recordings.
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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Jacob M. Elkins