An interventional study of 18F-FDG PET/MRI with additional DTI and rs-fMRI sequences in Glioblastoma, sponsored by Centre Paul Strauss. Not yet recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-04.
Sponsored by Centre Paul Strauss · Not applicable, Interventional, and Other
The aim of this study is to determine whether the diffuse cerebral metabolic disturbances observed in glioblastoma are exclusively linked to the direct and indirect effects of tumor infiltration (particularly structural disconnection), or whether they also reflect a more global alteration of neurometabolic and neurovascular coupling mechanisms.
This approach thus aims to better understand the pathophysiological basis of cognitive impairment in glioblastoma and to characterize the impact of the disease at the level of brain networks.
1,920 studies on the registry are indexed under Glioblastoma; 450 are open to participants now.
This study's planned enrollment of 80 is above the median of 36 across 1,618 interventional studies indexed under Glioblastoma.
Browse Glioblastoma studies →Centre Paul Strauss is the lead sponsor of 30 studies on the registry; 20 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients treated in the Nuclear Medicine \& Molecular Imaging Department of the Strauss Institute for PET/MRI scans for:
Exclusion Criteria:
Other: 18F-FDG PET/MRI with additional DTI and rs-fMRI sequences
fluorodeoxyglucose (Fluor18) (18F-FDG) PET/MRI with additional DTI and rs-fMRI sequences correlation with neuropsychological tests
Correlation between cortical energy activity (FDG PET), axonal morphological connectivity (DTI - MRI), synchronous neuronal activity (rs-fMRI), and preoperative neuropsychological performance before surgery
Time frame: Before surgery
correlation between cortical energy activity (FDG PET), axonal morphological connectivity (DTI - MRI), synchronous neuronal activity (rs-fMRI), and preoperative neuropsychological performance after surgery
Time frame: After surgery, through the study, i.e. for a maximum of 2 years
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Centre Paul Strauss