ClinicalTrials.gg
Not yet recruitingNCT07624916Updated Jun 3, 2026

Transversus Abdominis Plane and Rectus Sheath Block for Robotic Colectomy

A Phase 4 interventional study of Ropivacaine and Saline in Rectus Sheath Block, Transversus Abdominis Plane Block and Enhanced Recovery After Surgery, sponsored by Tri-Service General Hospital (TSGH). Not yet recruiting at 1 site in Taiwan. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-06-03.

Sponsored by Tri-Service General Hospital (TSGH) · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
20 Years to 80 Years
Sex
All
01

Study summary

This study aimed to evaluate the impact of ultrasound-guided bilateral transversus abdominis plane block combined with rectus sheath block on postoperative pain and recovery after robotic colectomy under an enhanced recovery after surgery (ERAS) protocol.

Read the detailed description

Postoperative pain remains an important concern after robotic colectomy despite the implementation of enhanced recovery after surgery (ERAS) protocols. Although robotic colectomy is associated with smaller incisions and faster recovery than conventional open surgery, postoperative pain may still impair early ambulation, gastrointestinal recovery, and patient satisfaction. Multimodal analgesia strategies, including acetaminophen and nonsteroidal anti-inflammatory drugs, are commonly used in ERAS pathways to reduce opioid consumption and opioid-related adverse effects. However, postoperative pain during movement and opioid requirements remain clinically relevant issues.

Ultrasound-guided transversus abdominis plane (TAP) block has been reported to reduce postoperative pain and opioid consumption after colorectal surgery. In addition, rectus sheath block (RSB) may provide further analgesic benefit for midline abdominal incision pain. Nevertheless, the additional clinical benefit of combining TAP block and RSB in patients undergoing robotic colectomy within an established ERAS pathway has not been fully investigated.

This study aimed to evaluate the impact of ultrasound-guided bilateral TAP block combined with RSB on postoperative pain and recovery following robotic colectomy. Additionally, we investigated the influence of TAP block combined with RSB on postoperative opioid consumption, postoperative nausea and vomiting, early ambulation, gastrointestinal recovery, and length of hospital stay after robotic colectomy under ERAS management.

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Conditions studied

  • Rectus Sheath Block
  • Transversus Abdominis Plane Block
  • Enhanced Recovery After Surgery
  • Robotic Surgery
  • Colorectal Cancer

Keywords

  • colorectal cancer
  • robotic colectomy
  • enhanced recovery after surgery
  • transversus abdominis plane block
  • rectus sheath block
03

In context

Colorectal Neoplasms

6,541 studies on the registry are indexed under Colorectal Neoplasms; 1,667 are open to participants now.

This study's planned enrollment of 90 is above the median of 76 across 4,800 interventional studies indexed under Colorectal Neoplasms.

Browse Colorectal Neoplasms studies →

Lead sponsor

Tri-Service General Hospital (TSGH) is the lead sponsor of 38 studies on the registry; 12 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients scheduled for elective robotic colorectal cancer surgery for the first time

Exclusion criteria

Exclusion Criteria:

  • Age \< 18 years or age > 80 years
  • Allergic to any medication in the protocol
  • Infection over the injection site
  • Chronic pain history
  • Severe hepatic or renal insufficiency
  • Pregnancy
  • Emergency surgery
  • Refusal to join the study
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Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
90 participants (estimated)

Study arms

  • Experimental
    TAP+RSB-R group

    TAP+RS block with ropivacaine and standard analgesic care

    Drug: Ropivacaine

  • Placebo comparator
    TAP+RSB-S group

    TAP+RS block with saline and standard analgesic care

    Drug: Saline

Interventions

  • TAP+RS block using ropivacaine

  • DrugSaline

    TAP+RS block with saline

06

What researchers measure

Primary outcomes

  1. Visual Analogue Scale at Resting

    Time frame: Postoperative 48 hours

  2. Visual Analogue Scale at Movement

    Time frame: Postoperative 48 hours

  3. Postoperative Opioid Consumption

    Time frame: Postoperative 48 hours

Secondary outcomes

  1. Postoperative Adverse Event

    Time frame: From surgery until hospital discharge

  2. Time to First Ambulation

    Time frame: From surgery until hospital discharge

  3. Time to First Flatus

    Time frame: From surgery until hospital discharge

  4. Hospital Stay

    Time frame: At hospital discharge

07

Study locations

1 site
08

References and documents

Publications

  • Yang R, Wang J, Shi DW, Niu Y, Zhou XD, Liu Y, Xu GH. The Efficiency of Multipoint Rectus Sheath Block Based on Incision Location in Laparoscopic-Assisted Colorectal Surgery: A Randomized Clinical Trial. Dis Colon Rectum. 2023 Dec 1;66(12):1578-1586. doi: 10.1097/DCR.0000000000002895. Epub 2023 Jun 28. PubMed 37379171 ↗
  • Liu KY, Lu YJ, Lin YC, Wei PL, Kang YN. Transversus abdominis plane block for laparoscopic colorectal surgery: A meta-analysis of randomised controlled trials. Int J Surg. 2022 Aug;104:106825. doi: 10.1016/j.ijsu.2022.106825. Epub 2022 Aug 8. PubMed 35953018 ↗
  • Viderman D, Aubakirova M, Abdildin YG. Transversus Abdominis Plane Block in Colorectal Surgery: A Meta-Analysis. Front Med (Lausanne). 2022 Feb 23;8:802039. doi: 10.3389/fmed.2021.802039. eCollection 2021. PubMed 35295183 ↗
  • Liu L, Xie YH, Zhang W, Chai XQ. Effect of Transversus Abdominis Plane Block on Postoperative Pain after Colorectal Surgery: A Meta-Analysis of Randomized Controlled Trials. Med Princ Pract. 2018;27(2):158-165. doi: 10.1159/000487323. Epub 2018 Feb 1. PubMed 29402875 ↗
  • Hain E, Maggiori L, Prost A la Denise J, Panis Y. Transversus abdominis plane (TAP) block in laparoscopic colorectal surgery improves postoperative pain management: a meta-analysis. Colorectal Dis. 2018 Apr;20(4):279-287. doi: 10.1111/codi.14037. PubMed 29381824 ↗

Individual participant data

Plan to share: No — There is no plan to share

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 3, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07624916
Lead sponsor
Tri-Service General Hospital (TSGH)
Responsible party
Wei-Cheng Tseng (Principal Investigator, Tri-Service General Hospital (TSGH)) — Principal investigator
First posted
Jun 3, 2026
Start date
Jun 1, 2026 (estimated)
Primary completion
Mar 31, 2028 (estimated)
Completion
Mar 31, 2028 (estimated)
Last update
Jun 3, 2026

Study contacts

Wei-Cheng Tseng, MD
Contact
ndmc_wechern@yahoo.com.tw
886-2-8792-3311 ext. 24159

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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Studies of the drug tested here: Ropivacaine

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