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CompletedNCT07583901Updated Jul 7, 2026

Effects of Gaze Stabilization Exercises and Optokinetic Training in Peripheral Vestibular Disorders

An interventional study of Gaze stabilization exercises and Optokinetic training in Nystagmus and Optokinetic Nystagmus, sponsored by Foundation University Islamabad. Completed at 1 site in Pakistan. Open to participants aged 35 Years to 55 Years. Per ClinicalTrials.gov, last updated 2026-07-07.

Sponsored by Foundation University Islamabad · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 5 months after the study started (first participant enrolled Nov 2025, registered May 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
32
Allocation
Randomized
Ages
35 Years to 55 Years
Sex
All
01

Study summary

This study compares the effectiveness of Gaze Stabilization Exercises and Optokinetic Training in improving dizziness, balance, and confidence in individuals with peripheral vestibular disorders.

Read the detailed description

Peripheral vestibular disorders (PVD) commonly cause dizziness, postural instability, and decreased balance confidence, which increase the risk of falls and limit participation in daily activities. Vestibular rehabilitation is widely used to manage these symptoms. Among rehabilitation approaches, Gaze Stabilization Exercises (GSE) aim to improve vestibulo-ocular reflex function, while Optokinetic Training (OKT) promotes symptom habituation through visual motion stimulation. However, the comparative effectiveness of these two interventions remains unclear.

This study aims to compare the effects of GSE and OKT on dizziness severity, postural stability, and balance confidence in individuals with peripheral vestibular disorders. Participants will undergo intervention sessions three times per week for six weeks. Outcome measures will be assessed at baseline, mid-intervention (week 3), and post-intervention (week 6).

Primary and secondary outcomes will include the Dizziness Handicap Inventory (DHI), Dynamic Gait Index (DGI), and the Activities-specific Balance Confidence (ABC) Scale. Data will be analyzed using SPSS statistical software. It is hypothesized that both interventions will improve dizziness, balance, and confidence, though differences in effectiveness may exist between the two approaches.

The findings of this study are expected to contribute to evidence-based vestibular rehabilitation by identifying effective intervention strategies. The results may help clinicians design personalized rehabilitation programs aimed at reducing fall risk, improving functional mobility, and enhancing quality of life in individuals with peripheral vestibular disorders.

02

Conditions studied

  • Nystagmus
  • Optokinetic Nystagmus

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03

In context

Nystagmus, Pathologic

27 studies on the registry are indexed under Nystagmus, Pathologic; 3 are open to participants now.

This study's enrollment of 32 is below the median of 48 across 17 interventional studies indexed under Nystagmus, Pathologic.

Browse Nystagmus, Pathologic studies →

Lead sponsor

Foundation University Islamabad is the lead sponsor of 255 studies on the registry; 142 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Male and female patients aged 35-55 years
  • Complaining of dizziness for at least three months
  • Reporting at least one dizziness episode per month
  • Medical diagnosis of chronic peripheral vestibular disease
  • Willingness to participate and provide

Exclusion criteria

Exclusion Criteria:

  • Medical history or signs of central nervous system disorders and/or psychiatric disorders
  • Uncontrolled hypertension and diabetes
  • Incapacity to understand and follow simple verbal commands
  • Inability to independently remain in standing position
  • Severe visual impairment or visual impairment not compensated by corrective lenses
  • Orthopedic disorders resulting in movement limitation or use of lower-limb prostheses
  • Previous body balance rehabilitation in the last six months
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

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05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
32 participants (actual)

Study arms

  • Experimental
    Gaze Stabilization Exercises

    Purpose: Enhance gaze stability, postural control, and confidence in functional activities. Description: Week 1: Sitting, VOR x1 horizontal, fixate on near target - start gaze stability. Week 2: Sitting, VOR x1 vertical, near/far target - increase head speed. Week 3: Standing, VOR x1 horizontal, fixate on target - improve upright balance. Week 4: Standing, VOR x1 with busy background - challenge visual-vestibular interaction. Week 5: Standing, VOR x2 horizontal/vertical - advanced gaze stabilization. Week 6: Standing, VOR x2 with busy background - integrate dynamic visual input.

    Procedure: Gaze stabilization exercises

  • Active comparator
    Optokinetic Training

    Purpose: Reduce visually induced dizziness, enhance balance, and improve confidence in daily activities. Description: Week 1: Horizontal stripes Week 2: Vertical motion Week 3: Real-world videos Week 4: Crowded/busy scenes Week 5: Moving environment + light movement Week 6: Provocative videos (spirals/crowded)

    Procedure: Optokinetic training

Interventions

  • ProcedureGaze stabilization exercises

    The control group received gaze stabilization exercises for 6 weeks, comprising 18 supervised sessions conducted three times weekly. Training included VOR x1 and VOR x2 exercises in horizontal and vertical planes using near and far visual targets. Exercises progressed from sitting to standing positions and from simple to visually busy backgrounds. Each session also included balance training activities such as weight shifts, tandem stance, pivot turns, and walking with head movements, with rest periods provided as needed.

  • ProcedureOptokinetic training

    The experimental group underwent optokinetic training for 6 weeks with 18 supervised sessions conducted three times weekly. Participants were exposed to progressively challenging moving visual stimuli, including distortion patterns, busy street scenes, motorway driving videos, and chequerboard jiggle/wrap patterns. Training advanced from sitting to standing with dynamic movements as visual complexity increased. Baseline and task-specific balance exercises were incorporated into every session, with adequate rest periods provided when necessary.

06

What researchers measure

Primary outcomes

  1. Dizziness

    It will be measured by using Dizziness Handicap Inventory. Score Interpretation: 0-30: Slight or Mild Handicap 31-60: Moderate Handicap 61-100: Severe Handicap

    Time frame: 6 weeks

  2. Postural Stability

    It will be measured by using Dynamic Gait Index (DGI). Interpretation: ≤19 = increased fall risk 20-24 = safe ambulation Higher scores = better gait performance and dynamic balance Lower scores = impaired gait and higher fall risk

    Time frame: 6 weeks

  3. Balance Confidence

    It will be measured by using Activities-specific Balance Confidence (ABC) Scale. Interpretation: \<50% = low level of physical functioning and high fall risk 50-80% = moderate level of functioning80% = high level of functioning and confidence Higher scores = greater balance confidence Lower scores = fear of falling and reduced functional independence

    Time frame: 6 weeks

07

Study locations

1 site
  • Foundation University College of Physical Therapy
    Islamabad, 44000, Pakistan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 7, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07583901
Responsible party
Sponsor
First posted
May 13, 2026
Start date
Nov 18, 2025
Primary completion
May 1, 2026
Completion
May 1, 2026
Last update
Jul 7, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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