An interventional study of Sequential Prefrontal Alpha-Theta Neurofeedback Training in Alcohol Use Disorder, sponsored by Seoul University of Buddhism. Completed at 1 site in South Korea. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-13.
Sponsored by Seoul University of Buddhism · Not applicable, Interventional, and Treatment
This study examined the effects of sequential prefrontal alpha-theta neurofeedback training on abstinence self-efficacy, mindfulness, and brain electroencephalography (EEG) activity in adults with Alcohol Use Disorder (AUD). Participants in the experimental group received 24 sessions of neurofeedback over 8 weeks (3 sessions per week, 30 minutes per session), while a control group received no intervention. EEG and self-report measures were assessed at baseline and post-intervention.
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This study's enrollment of 17 is below the median of 87 across 1,371 interventional studies indexed under Alcoholism.
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Exclusion Criteria:
24 sessions of sequential prefrontal alpha-theta neurofeedback training over 8 weeks (3 sessions/week, 30 min/session). Each session: 5 min alpha feedback (8-12 hertz \[Hz\]) followed by 25 min theta feedback (4-7 Hz) at Fp1/Fp2, delivered via ocean wave and birdsong audio while eyes closed. Device: Power Nap (Neuro21, Korea).
Behavioral: Sequential Prefrontal Alpha-Theta Neurofeedback Training
Participants continued usual daily activities for 8 weeks without any intervention. Pre- and post-test assessments (EEG and self-report measures) were conducted.
Operant conditioning-based neurofeedback: 5 min alpha (8-12 Hz) + 25 min theta (4-7 Hz) at prefrontal sites Fp1/Fp2 per session; 24 sessions over 8 weeks supervised by a certified practitioner. Audio feedback (ocean waves for alpha, birdsong for theta) delivered via Power Nap device (Neuro21, Korea) while participants remained eyes-closed and seated.
Abstinence Self-Efficacy
Total score on the Alcohol Abstinence Self-Efficacy Scale (AASE; Korean adaptation), a 20-item scale with four subscales (Negative Affect, Social/Positive Emotions, Physical and Other Concerns, Withdrawal and Urges), each rated 0-4; higher scores indicate greater confidence in maintaining abstinence.
Time frame: Baseline (Week 0) and post-intervention (Week 8)
Mindfulness
Total score on the Mindfulness Scale (20 items, 4 subscales: Decentered Attention, Nonjudgmental Acceptance, Present-Moment Awareness, Attentional Focus), rated 1-5 (reverse-scored); higher scores indicate greater mindfulness.
Time frame: Baseline (Week 0) and post-intervention (Week 8)
EEG Relative Power
Relative spectral power (% of total power) across delta (1-4 Hz), theta (4-8 Hz), alpha (8-12 Hz), beta (13-30 Hz), and sensorimotor rhythm (SMR; 12-15 Hz) bands at prefrontal sites (Fp1, Fp2), measured using eyes-closed resting EEG with the NeuroBrain system.
Time frame: Baseline (Week 0) and post-intervention (Week 8)
Plan to share: No
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This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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