CClinicalTrials.gg
Active, not recruitingNCT07578961Updated May 11, 2026

Combined Effects of Tactile Kinesthetic Stimulation With Neural Mobilization in Stroke Patients

An interventional study of Tactile kinesthetic stimulation with neural mobilization and kinesthetic therapy in Stroke, sponsored by Riphah International University. Active, not recruiting at 1 site in Pakistan. Open to participants aged 45 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-05-11.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jun 2026, 4 months ago, but the record still lists the study as active, not recruiting.
  • Registered 1 year 1 month after the study started (first participant enrolled Apr 2025, registered May 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
53
Allocation
Randomized
Ages
45 Years to 65 Years
Sex
All
01

Study summary

Combined Effects of Tactile -kinesthetic stimulation with Neural mobilization on sensory and motor functions of upper limb in stroke patients

Read the detailed description

Stroke ranks among the primary causes of lasting disability, frequently leaving the upper limb weak, numb, or clumsy and thereby curtailing daily independence and overall well-being. Although multiple therapy regimens appear helpful, research to date Meestal tests each method alone, obscuring how paired sensory and motor targets might accelerate recovery. The present study investigates combined the effect of tactile-kinesthetic input with neural mobilization against standard care, hypothesizing that the blend will produce broader gains in sensation and movement.

This randomized clinical trial will be conducted at Ittefaq Hospital (Trust) Lahore and Gulab Devi Chest Hospital Lahore over duration of 11 months. The sample size will be (53) participants. Participants which meet the inclusion criteria will be taken through non-probability convenience sampling technique, which will further be randomized through lottery method. Group A (27) participants will be assigned to combined tactile kinesthetic stimulation plus neural mobilization and Group B (27)participants will be assigned to conventional therapy. Data will be collected through different assessment tools, including Fugyl-Meyer Assessment for motor function, Nottingham Sensory Assessment Scale (NAS) for sensory function. Pre-interventions assessments will be conducted for both groups. The effects of the interventions will be measured at pre-treatment and post-treatment of 6 weeks. Data analysis will be performed by using SPSS 26 software.

02

Conditions studied

  • Stroke

Browse trials for

Keywords

  • Chronic stroke rehabilitation
  • neural mobilization
  • tactile kinesthetic stimulation
  • tactile therapy
03

In context

Stroke

7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.

This study's planned enrollment of 53 is close to the median of 50 across 5,369 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
45 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age between 45 - 65 years
  • Both gender Male and Female
  • Diagnosed with chronic stroke stated as occurring 6 month to 12 month .
  • Sensory impairment - loss of tactile and proprioception NSA ( \< 7/12)
  • Motor impairment - lack in full strength and coordination ( Brunnstrom >3)
  • Scored 24 or higher on the Mini-Mental State Examination, indicating sufficient cognition to follow study instructions.

Exclusion criteria

Exclusion Criteria:

  • Severe cognitive or communication difficulties that would prevent meaningful involvement in therapy or testing.
  • Comorbid conditions that impair upper-limb function, including arthritis, prior fractures, or similar disorders.
  • Neurological conditions other than stroke that could interfere with study outcomes
  • Engagement in any other rehabilitation program during the trial period.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
53 participants (estimated)

Study arms

  • Experimental
    Combine effects of Tactile with neural of sensory and motor functions of upper limb stroke

    Tactile Kinesthetic with Neural Mobilization: participants receive TKS WITH NM for 20 mins for 3 days per week for 4 weeks

    Other: Tactile kinesthetic stimulation with neural mobilization

  • Active comparator
    Combine effects of Tactile with neural mobilization of sensory and motor functions of upper limb str

    Tks With Nm receive 20 mins therapy for 3 days per week

    Other: kinesthetic therapy

Interventions

  • OtherTactile kinesthetic stimulation with neural mobilization

    The therapist rests a light touch on the limb, applying only the weight of fingertips Soft, gliding strokes travel across the skin, delivered with the very tips of the fingers Pressure remains steadily upon targeted patches of tissue without sliding away Measured, rhythmical strokes creep up and down the length of the arm or leg Smooth silk, rough jute, coarse sponge, and other materials are brushed over the skin in turn.Slowly glide the median nerve by extending wrist and fingers while gently abducting the shoulder.

  • Otherkinesthetic therapy

    Median nerve mobilization: Slowly glide the median nerve by extending wrist and fingers while gently abducting the shoulder. Ulnar nerve mobilization: Control elbow flexion and wrist extension while holding shoulder in slight abduction Radial nerve mobilization: Passively flex the wrist, pronate the forearm, and depress the shoulder to slide the radial nerve

06

What researchers measure

Primary outcomes

  1. 1.Fugl-Meyer Assessment (FMA)

    The Fugl-Meyer Assessment (FMA) was developed specifically for stroke survivors and is a performance-based tool that gauges sensorimotor deficits in people living with hemiplegia. The FMA examines five key areas: voluntary motor control, sensory perception, balance, passive joint range of motion, and joint-related pain. Within this battery, the motor section commands the most attention; it rates movement, coordination, and reflex activity in the arms and legs, yielding a ceiling score of 100 points (66 for the arm and 34 for the leg).

    Time frame: baseline with 4 week

  2. 2.Nottingham Sensory Assessment (NSA)

    The Nottingham Sensory Assessment, or NSA, provides clinicians with a standard method for mapping sensory loss after a stroke. Designed to examine both arms and legs, it centers on three core domains: touch, proprioception, and stereognosis. Within the protocol, practitioners test responses to light touch, gentle pressure, pinprick, temperature changes, and passive joint positioning. Because around half of all stroke survivors carry hidden somatosensory deficits that often impede movement, the tool is essential for early identification.

    Time frame: baseline with 4 week

07

Study locations

1 site
  • Lahore, Punjab Province 54000, Pakistan
08

References and documents

Publications

  • Battesha HHM, Wadee AN, Shafeek MM, Tawfick AM, Ibrahim HM. Maze Control Training on Kinesthetic Awareness in Patients with Stroke: A Randomized Controlled Trial. Rehabil Res Pract. 2022 Feb 24;2022:5063492. doi: 10.1155/2022/5063492. eCollection 2022. PubMed 35251715 ↗
  • Takahashi R, Koiwa M, Ide W, Okawada M, Akaboshi K, Kaneko F. Visually Induced Kinaesthetic Illusion Combined with Therapeutic Exercise for Patients with Chronic Stroke: A Pilot Study. J Rehabil Med. 2022 Apr 7;54:jrm00276. doi: 10.2340/jrm.v54.29. PubMed 35266005 ↗
  • Afzal MR, Pyo S, Oh MK, Park YS, Yoon J. Evaluating the effects of delivering integrated kinesthetic and tactile cues to individuals with unilateral hemiparetic stroke during overground walking. J Neuroeng Rehabil. 2018 Apr 16;15(1):33. doi: 10.1186/s12984-018-0372-0. PubMed 29661237 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 11, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07578961
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
May 11, 2026
Start date
Apr 5, 2025
Primary completion
Jun 3, 2026 (estimated)
Completion
Jul 6, 2026 (estimated)
Last update
May 11, 2026

Study contacts

Sabiha Arshad, Ms
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion