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Not yet recruitingNCT07578779Updated Jun 10, 2026

Effects of Frenkels Exercises and Electrical Muscle Stimulation on Stroke Patients

An interventional study of Frenkels exercise with EMS and Conservative treatment in Stroke, sponsored by Riphah International University. Not yet recruiting. Open to participants aged 50 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-06-10.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Randomized
Ages
50 Years to 65 Years
Sex
All
01

Study summary

To determine the combined effects of frenkel's exercises and electrical muscle stimulation on coordination, balance and proprioception in stroke patients.

02

Conditions studied

  • Stroke

Keywords

  • Balance
  • Coordination
  • EMS
  • Ischemia
  • Proprioception
  • Rehabilitation
  • Stroke
03

Who can participate

Ages eligible
50 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Typically 50-65 years old.(14)
  • Both male and female are included
  • Patients with subacute ischemic stroke (hemiplegia).(15)
  • Ability to walk independently for at least 10minutes.(16)
  • Diagnosis of a first-time stroke or without sequel of a previous stroke(15)
  • MOCA score>26 to confirm adequate cognitive function.
  • Brunnstrom exercise recovery stages of 3-4 or higher(17)
  • Voluntarily provided informed consent prior to participating

Exclusion criteria

Exclusion Criteria:

  • Patients with severe cognitive impairment or dementia.(16)
  • Patients with unstable medical conditions, such as uncontrolled hypertension or cardiac disease.
  • Patients with recent surgery or injury that may affect participation in the study.
  • Patients with contraindications to electrical muscle stimulation (EMS), such as unstable cardiopulmonary medical conditions pacemakers or metal implants
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
38 participants (estimated)

Study arms

  • Experimental
    Frenkels exercise with EMS

    Participant will receive EMS for 10 minutes and Frenkels exercise for 20 minutes for 3 days per week for 8 weeks

    Other: Frenkels exercise with EMS

  • Active comparator
    Conservative Treatment

    Participants will receive routine therapy for 30 minutes. It could be hot pack, IR with routine exercises for 3 days per week for 8 weeks.

    Other: Conservative treatment

Interventions

  • OtherFrenkels exercise with EMS

    Group A will include 19 participants. Participant will receive EMS for 10 minutes and Frenkels exercise for 20 minutes for 3 days per week for 8 weeks In Week 1-2 Investigator will apply 50Hz EMS pulse duration of 150 μs, intermittent with 5s of EMS stimulation to perform the movement and 10s of rest stimulation for adaptation while focusing lower limb exercises in according to frenkles exercises for 20 min in lying position Week 3-4: 60 Hz EMS stimulation applied pulse duration of 200 μs, intermittent with 5 s of EMS stimulation to perform the movement and 10 s of rest with frenkles exercises in sitting position Week 5-6 Frequency of 70 Hz pulse duration of 250 μs, intermittent with 5 s of EMS stimulation to perform the movement and 10 s of rest EMS stimulation will be applied with frenkles exercises in standing position Week 7-8: In progression, Frequency of 85 Hz and pulse duration of 300 μs, intermittent with 5 s of EMS stimulation to perform the movement and 10 s of rest

  • OtherConservative treatment

    Group B will also include 19 participants. Each participant will receive routine therapy for 30 minutes. It could be hot pack, IR with routine exercises for 3 days per week for 8 weeks. Weeks 1-2: Initial Phase 1. Breathing exercises 2. Range of motion exercises 3. Seated exercises Weeks 3-4: Strengthening Phase Resistance band exercises: Upper and lower limb strengthening b) Weight-bearing exercises c) Gait training: Walking with support d) Balance exercises: Weeks 5-6 Functional Phase 1. Functional activities: Reaching, scooting, transferring 2. Gait training: Walking without support, navigating obstacles 3. Balance exercises: Dynamic balance, reaction training 4. Strengthening exercises: Weeks 7-8: Advanced Phase 1. Advanced gait training: Stair climbing, curbs, uneven surfaces 2. Complex functional activities: Cooking, dressing, household chores

05

What researchers measure

Primary outcomes

  1. The Berg Balance Scale (BBS)

    It's a 14-item performance-based measure, meaning it assesses how well a person can perform specific tasks related to balance. Each item is scored on a 5-point scale (0-4), with higher scores indicating better balance, and a total score range of 0-56.

    Time frame: Baseline and 8th week

  2. The Nottingham Sensory Assessment (NSA)

    NSA is used to evaluate sensory impairments, particularly in individuals who have experienced stroke. scores ranging from 0 (extreme difficulty/unable to perform) to 4 (no difficulty) for each item.

    Time frame: baseline and 8th week

  3. The Lower Extremity Motor Coordination Test (LEMOCOT)

    (LEMOCOT) scoring scale involves assessing an individual's ability to perform specific lower extremity movements, with scores ranging from 0 (extreme difficulty/unable to perform) to 4 (no difficulty) for each item. The total score is obtained by summing the scores of all items, with a higher score indicating better motor coordination.

    Time frame: Baseline and 8th Week

06

Study locations

No study locations are listed for this record.

07

References and documents

Publications

  • 1. Ko EJ, Chun MH, Kim D-Y, Kang Y, Lee SJ, Yi JH, et al. Frenkel's exercise on lower limb sensation and balance in subacute ischemic stroke patients with impaired proprioception. Neurology Asia. 2018;23(3).
  • Shoeb M, Mishra A, Yadav KK, Kumar S, Yadav S. Effect of BAPS Board Versus Frenkel Exercise on Balance in Stroke Patient's-A Pilot Study.
  • Yoo HJ, Park S, Oh S, Kang M, Seo Y, Kim BG, Lee SH. Effects of electrical muscle stimulation on core muscle activation and physical performance in non-athletic adults: A randomized controlled trial. Medicine (Baltimore). 2023 Jan 27;102(4):e32765. doi: 10.1097/MD.0000000000032765. PubMed 36705372 ↗
  • Haque S. Effectiveness of frankel exercise to improve balance and function after stroke: Bangladesh Health Professions Institute, Faculty of Medicine, the University …; 2023.
  • Khan S, Shahid W, Khalid R, Pervez M, Hameed R, Khaliq S. Effects of Proprioceptive Neuromuscular Facilitation with and without Electrical Muscle Stimulation on spasticity, gait and lower limb function in chronic stroke patients. Journal of Health and Rehabilitation Research. 2024;4(3):1-6.
  • Arif A, Arshad K, Tariq S, Sundas S, Tariq N, Kabir A, et al. COMPARATIVE EFFECTS OF VIRTUAL REALITY AND FRENKEL'S EXERCISES ON BALANCE, GAIT AND QUALITY OF LIFE IN PATIENTS WITH STROKE. Insights-Journal of Health and Rehabilitation. 2024;2(2 (Health & Rehab)):459-67.

Individual participant data

Plan to share: No

08

Registry details

Key details

Study ID
NCT07578779
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
May 11, 2026
Start date
Jun 20, 2026 (estimated)
Primary completion
Aug 1, 2026 (estimated)
Completion
Aug 1, 2026 (estimated)
Last update
Jun 10, 2026

Study contacts

Imran Amjad, Phd
Contact
imranamjad@riphah.edu.pk
03324390215
Sabiha Arshad, M.Phill
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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