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RecruitingNCT07566975Updated May 5, 2026

Real-World Assessment of VEVYE® for Short-Term Symptom and Sign Improvement of Dry Eye Disease in a Neuro-Ophthalmology Clinic: A 6-Month Prospective Observational Study

An observational study in Dry Eye, sponsored by Neuro-Ophthalmology of Texas. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-05.

Sponsored by Neuro-Ophthalmology of Texas · Observational

From the registry’s dates

  • Started Mar 2026; still recruiting 6 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years and older
Sex
All
01

Study summary

patients from a Neuro Ophthalmology who have dry eye, some of which have neurotrophic keratitis are being analyzed after treatment with Vevye

02

Conditions studied

  • Dry Eye

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Keywords

  • Neurotrophic Keratitis
  • Dry Eye
03

In context

Dry Eye Syndromes

1,292 studies on the registry are indexed under Dry Eye Syndromes; 191 are open to participants now.

This study's planned enrollment of 50 is below the median of 90 across 171 observational studies indexed under Dry Eye Syndromes.

Browse Dry Eye Syndromes studies →

Lead sponsor

This is the only study on the registry with Neuro-Ophthalmology of Texas as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Dry Eye Disease in a Neuro Ophthalmology clinic

Inclusion criteria

  • Age18 yr or older Diagnosis of neuro-ophthalmic condition Clinical diagnosis of dry eye disease OSDI score of 23 or greater at baseline Objective sign present Indicated for VEVYE prior to enrollment Ability and willingness to complete study visits and questionnaires

Exclusion criteria

Exclusion Criteria:

  • Patients with a corneal ulcer Use of another cyclosporine or lifitegrast product within 30 days of baseline Ocular surgery within 30 prior to baseline Active ocular infection or severe ocular surface condition unrelated to DED Contact lens wearers ( must be off contacts for 30 days and the duration of trial) Any condition that prevents compliance or informed consent Subjects with severe scarring / zero sensitivity
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No

Groups and cohorts

  • Dry Eye without neurotrophic changes

    Other: Cyclosporine ophthalmic solution 0.1%

  • Dry Eye with neurotrophic changes

    Other: Cyclosporine ophthalmic solution 0.1%

Interventions

  • OtherCyclosporine ophthalmic solution 0.1%

    one drop in both eyes twice a day

    Also known as: Vevye

06

What researchers measure

Primary outcomes

  1. Corneal fluorescein staining

    pre vs post treatment

    Time frame: Baseline compared to week 4

07

Study locations

1 of 1 sites recruiting
  • Neuro Ophthalmology of TX
    Houston, Texas 77074, United States
    Recruiting
08

References and documents

Individual participant data

Plan to share: Yes — results of pre and post treatment data

Supporting information: Sap

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 5, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07566975
Lead sponsor
Neuro-Ophthalmology of Texas
Collaborators
Harrow Inc
Responsible party
Sponsor
First posted
May 5, 2026
Start date
Mar 31, 2026
Primary completion
Nov 30, 2026 (estimated)
Completion
Nov 30, 2026 (estimated)
Last update
May 5, 2026

Study contacts

Laura Perez
Contact
lperez@neuroeye.com
12817238593
Rosa A Tang, MD
Contact
lperez@neuroeye.com
713-258-0009
Rosa A. Tang
principal investigator · Neuro Ophthalmology of TX

Oversight

Data monitoring committee
No
FDA-regulated drug
Yes
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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