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CompletedNCT07558512Updated May 8, 2026

Risk Factors and a Predictive Nomogram for Acute Moderate-to-severe Postoperative Pain After Achilles Tendon Surgery

An observational study in Postoperative Pain, sponsored by Min Li. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-08.

Sponsored by Min Li · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
489
Ages
18 Years and older
Sex
All
01

Study summary

This is a single-center retrospective cohort study to identify independent risk factors and develop a predictive nomogram for moderate-to-severe pain within 24 hours after Achilles tendon surgery.

02

Conditions studied

  • Postoperative Pain

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03

In context

Pain, Postoperative

5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.

This study's enrollment of 489 is above the median of 102 across 608 observational studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Min Li is the lead sponsor of 2 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study population consists of adult patients (≥18 years) who underwent Achilles tendon surgery at Peking University Third Hospital between January 2020 and December 2024. Eligible patients were those with complete perioperative data and standardized 24-hour postoperative pain assessments, meeting all inclusion and exclusion criteria of the study.

Inclusion criteria

  1. Age ≥ 18 years; American Society of Anesthesiologists (ASA) physical status classification Ⅰ\~Ⅲ;
  2. Clinically diagnosed with Achilles tendon rupture, Achilles tendinopathy, insertional Achilles tendinitis, Haglund's deformity, or other Achilles tendon disorders;
  3. Undergoing open or arthroscopic Achilles tendon surgery;
  4. Conscious and able to cooperate in surgery and postoperative pain assessment;
  5. Complete and accessible case data related to surgery, anesthesia, and postoperative pain assessment;
  6. Completion of at least 24 hours of standardized pain monitoring and clinical follow-up after surgery

Exclusion criteria

Exclusion Criteria:

  1. Missing or incomplete key clinical data such as pain assessment, surgery and anesthesia;
  2. Failure to complete 24-hour standardized pain monitoring after surgery; Perioperative unplanned secondary surgery or transfer to the intensive care unit (ICU);
  3. Patients with mental illness, cognitive dysfunction, or language communication barrier; History of alcohol or drug addiction Pain due to other acute or chronic diseases;
  4. Bilateral Achilles tendon surgery Concurrent surgery for other lower extremity injuries
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
489 participants (actual)
Patient registry
No

Interventions

  • OtherNo Study-Specific Intervention

    This is a retrospective observational cohort study. No study-specific intervention is being investigated; all patients received routine clinical care as per standard practice.

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What researchers measure

Primary outcomes

  1. Incidence of Moderate-to-Severe Acute Postoperative Pain

    Defined as a pain score ≥ 4 on the Numeric Rating Scale (NRS) or the need for rescue analgesia within the first 24 hours after Achilles tendon surgery. The NRS is an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain), where higher scores indicate greater pain severity (worse outcome).

    Time frame: Within 24 hours after surgery

Secondary outcomes

  1. Highest Postoperative Pain Score

    The maximum pain score recorded within 24 hours after Achilles tendon surgery, measured using the Numeric Rating Scale (NRS). The NRS is an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain), where higher scores indicate greater pain severity (worse outcome).

    Time frame: Within 24 hours after surgery

  2. Rescue Analgesia Requirement

    Proportion of patients requiring rescue analgesic medications within 24 hours after surgery.

    Time frame: Within 24 hours after surgery

  3. Incidence of Postoperative Nausea and Vomiting (PONV)

    Proportion of patients experiencing nausea or vomiting requiring antiemetic treatment within 24 hours after surgery.

    Time frame: Within 24 hours after surgery

  4. Postoperative Length of Hospital Stay

    Number of days from surgery to hospital discharge.

    Time frame: From surgery to hospital discharge (up to 7 days)

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Study locations

1 site
  • Peking University Third Hospital
    Beijing, 100191, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07558512
Lead sponsor
Min Li
Responsible party
Min Li (Chief Physician, Department of Anesthesiology, Peking University Third Hospital) — Sponsor-investigator
First posted
Apr 30, 2026
Start date
Apr 16, 2026
Primary completion
Apr 25, 2026
Completion
Apr 25, 2026
Last update
May 8, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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