An Early Phase 1 interventional study of Ozone Oil-based Gel in Pain and Dry Socket, sponsored by Cairo University. Active, not recruiting at 1 site in Egypt. Open to participants aged 21 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-28.
Sponsored by Cairo University · Early Phase 1, Interventional, and Prevention
Overall, 100 patients of both genders were included in the study, with indication of surgical extraction of lower third molar, positioned similarly after being clinically and radiographically checked by X-ray and orthopantomography. Each patient was subjected to both groups in separate sessions: treated with ozone gas and with CHX gel 1%. Data on pain intensity, number of taken analgesics- painkillers, and dry socket were recorded for 48 h and at Day 7
Overall, 100 patients of both genders were included in the study, with indication of surgical extraction of lower third molar, positioned similarly after being clinically and radiographically checked by X-ray and orthopantomography. Each patient was subjected to both groups in separate sessions: treated with ozone gas and with CHX gel 1%. Data on pain intensity, number of taken analgesics- painkillers, and dry socket were recorded for 48 h and at Day 7
Exclusion Criteria:
study group
Drug: Ozone Oil-based Gel
Overall, 30 patients of both genders were included in the study, with indication of surgical extraction of lower third molar, positioned similarly after being clinically and radiographically checked by X-ray and orthopantomography. Each patient was subjected to both groups in separate sessions: treated with ozone gas and with CHX gel 1%. Data on pain intensity, number of taken analgesics- painkillers, and dry socket were recorded for 48 h and at Day 7
Also known as: CHX Gel
pain severity
pain scale ( VAS ; visual analogue scale) (1-10)
Time frame: 7 days
dry socket incidence
bare socket (binary yes/no)
Time frame: 15 daays
Plan to share: No
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This study is active, not recruiting, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Cairo University