An interventional study of Standardized Test Meal in Meal Timing, Postprandial Glucose and Glycemic Response to Feeding in Healthy Participants, sponsored by King Faisal University. Completed at 1 site in Saudi Arabia. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-01.
Sponsored by King Faisal University · Not applicable, Interventional, and Basic science
This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults. Postprandial glucose will be assessed using the incremental area under the curve (iAUC) over 120 minutes.
King Faisal University is the lead sponsor of 15 studies on the registry; 2 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will consume a standardized test meal in the morning following an overnight fasting period of at least 8 hours. Postprandial glucose will be measured over 120 minutes.
Other: Standardized Test Meal
Participants will consume the same standardized test meal in the evening following a standardized fasting period of at least 8 hours prior to the test meal. Postprandial glucose will be measured over 120 minutes.
Other: Standardized Test Meal
The standardized test meal provided 50 g of carbohydrates of weighed portions of white bread and jam, served with 200 mL of water.
Incremental Area Under the Curve (iAUC) for Postprandial Glucose
The primary objective of this study is to investigate the effect of circadian timing of a standardized test meal (morning versus evening consumption) on postprandial glucose response in healthy adults, assessed as the incremental area under the curve (iAUC) for capillary blood glucose over 120 minutes following meal consumption
Time frame: Baseline to 120 minutes after consumption of the standardized test meal
Peak Postprandial Glucose (Morning vs Evening)
Peak capillary blood glucose concentration measured within 120 minutes after consumption of the standardized test meal, under morning and evening conditions
Time frame: Baseline to 120 minutes after consumption of the standardized test meal
Time to Peak Glucose (Morning vs Evening)
Time required to reach peak capillary blood glucose concentration following meal consumption, under morning and evening conditions.
Time frame: Baseline to 120 minutes after consumption of the standardized test meal
Postprandial Glucose Profile (Morning vs Evening)
Capillary blood glucose concentrations measured at predefined time points following consumption of the standardized test meal, under morning and evening conditions.
Time frame: Baseline, 15, 30, 60, 90, and 120 minutes after consumption of the standardized test meal
Night Eating Behavior
Night eating behavior will be assessed using the validated Night Eating Questionnaire to characterize nocturnal eating patterns and support interpretation of variability in postprandial glucose responses.
Time frame: Baseline
Sleep Duration and Quality
Sleep duration and quality will be assessed using a validated sleep questionnaire administered prior to each study visit to support interpretation of postprandial glucose responses.
Time frame: Baseline
Chronotype
Chronotype will be assessed at baseline using the validated Questionnaire to characterize individual circadian preference and support interpretation of postprandial glucose responses.
Time frame: Baseline
Plan to share: No — De-identified individual participant data (IPD) collected in this study will not be made publicly available. Data will be used for research purposes by the study investigators only
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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King Faisal University