An observational study in Chronic Periodontitis, Chronic Periodontitis Wth Diabetes Mellitus and Non-surgical Periodontal Treatment, sponsored by Amar h Zireg. Completed at 1 site in Algeria. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-28.
Sponsored by Amar h Zireg · Observational
This observational study documents the clinical outcomes of a proprietary, safe-to-swallow metabolic protocol for chronic gum disease. Based on 21 years of research and a focused 20-patient cohort, the study records visible clinical improvements in gingival inflammation and tissue color within 7 to 14 days. The protocol focuses on restoring the metabolic environment to achieve non-surgical periodontal pocket stabilization and natural tissue re-attachment.
377 studies on the registry are indexed under Chronic Periodontitis; 21 are open to participants now.
This study's enrollment of 20 is below the median of 80 across 65 observational studies indexed under Chronic Periodontitis.
Browse Chronic Periodontitis studies →Amar h Zireg is the lead sponsor of 3 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients aged 18 to 75 years diagnosed with chronic periodontitis, characterized by gingival inflammation, bleeding on probing, and periodontal pocket depths of 4mm or greater. The population includes individuals seeking non-surgical alternatives for gum tissue recovery.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Topical application of a proprietary, 100% food-grade (GRAS) nutraceutical formulation specifically designed for rapid gingival tissue regeneration and inflammation reversal. Key Performance Indicators: Speed: Clinical onset of action visible within 3 days. Safety: Completely safe for ingestion (edible), eliminating common side effects of chemical antiseptics like staining or taste alteration. Efficacy: Significant reduction in redness and bleeding (BOP) within 7 to 14 days, as demonstrated in our cohort of 20+ subjects. Mechanism: Supports the natural healing of the gum 'peau' (epithelium) through host-response modulation rather than harsh disinfection.
Topical application of a proprietary, 100% food-grade (GRAS) nutraceutical formulation specifically designed for rapid gingival tissue regeneration and inflammation reversal.Key Performance Indicators: Speed: Clinical onset of action visible within 3 days. Safety: Completely safe for ingestion (edible), eliminating common side effects of chemical antiseptics like staining or taste alteration. Efficacy: Significant reduction in redness and bleeding (BOP) within 7 to 14 days, as demonstrated in our cohort of 20+ subjects. Mechanism: Supports the natural healing of the gum 'peau' (epithelium) through host-response modulation rather than harsh disinfection."
Visible reduction in gingival inflammation and erythema (redness) observed within 7 to 14 days
Time frame: 7 to 14 days
Measurement of periodontal pocket depth reduction and tissue stability at 6 weeks
Time frame: 6 weeks
Ran from Jan 2026 to primary completion in Feb 2026, 1 month.
Of 21 observational studies under Chronic Periodontitis, half reached primary completion within 9 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 17. This study's 1 month is below that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Amar h Zireg