An interventional study of High Level Laser Therapy and Low Level Laser Therapy in Myofascial Pain Dysfunction Syndrome, sponsored by Cairo University. Not yet recruiting at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2026-04-15.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to evaluate and compare the effectiveness of modified laser therapy versus conventional laser therapy in managing pain and mandibular function in patients with chronic myofascial pain syndrome involving the masseter muscles. The main questions it aims to answer are:
Comparison Group:
Researchers will compare the experimental group receiving High-Intensity Laser Therapy (HLLT) to a comparator group receiving Low-Level Laser Therapy (LLLT) to see if the modified high-intensity approach provides superior pain relief and improved mandibular movement.
Participants will:
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This study's planned enrollment of 40 is below the median of 60 across 1,035 interventional studies indexed under Fibromyalgia.
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Exclusion Criteria:
1- Patients with TMJ pain, or those who had any previous treatment for TMD 2- Patients with any history of cervical or degenerative conditions, any surgery or trauma to the neck during last year 3- Previous treatment of MPDS during last year 4- Confirmed diagnosis of fibromyalgia or rheumatoid arthritis 5- Patients with dark skin tone or chubby face
Device: High Level Laser Therapy
Device: Low Level Laser Therapy
Laser energy density of 3 KJ will be applied to the masseter muscles using an epic-x940 nm diode laser, with 12 irradiation sessions delivered over one month. The mode of laser was a continuous wave irradiation for 5 minutes, distance to Tissue\~1 cm, and the area of the laser delivery tip was 5 cm2. The trigger point was identified within the affected muscle.
Laser energy density of 1.5 KJ will be applied to the masseter muscles using an epic-x940 nm diode laser (BioLase, USA), with 12 irradiation sessions delivered over one month. The mode of laser was a continuous wave irradiation for 5 minutes, distance to Tissue\~1 cm, and the area of the laser delivery tip was 5 cm2. The trigger point was identified within the affected muscle.
Pain Assessment
Time frame: Pain will be assessed using a numerical rating scale (NRS) at rest and during mouth opening at the following follow up time points: at each session, 1, 3 months and 6 months.
Maximal incisal opening
Time frame: Maximal incisal opening is measured at each session, 1, 3 months and 6 months.
Plan to share: Undecided — The data will be retained by the investigators for further internal analysis and research pruposes.
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Cairo University