An observational study in Pnes, sponsored by Tepecik Training and Research Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-13.
Sponsored by Tepecik Training and Research Hospital · Observational
This retrospective observational study evaluates semiological and electroclinical characteristics of psychogenic nonepileptic seizures (PNES) in adult patients who underwent video-EEG monitoring. The study aims to identify distinct semiological patterns and classify PNES events based on observable ictal features recorded during video-EEG monitoring.
Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on electroencephalography (EEG). Video-EEG monitoring is the gold standard for diagnosis.
In this retrospective observational study, video-EEG recordings and clinical data of 52 adult patients diagnosed with PNES were reviewed. Semiological features observed during recorded events were systematically evaluated and coded as binary variables.
Hierarchical cluster analysis (Ward's method with squared Euclidean distance) was used to identify semiological patterns. The aim was to define clinically meaningful clusters of PNES events and to describe their demographic and clinical correlates.
This study population consists of adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent long-term video-EEG monitoring in a tertiary epilepsy center. All included patients had at least one recorded PNES event and sufficient clinical data available for retrospective analysis. Patients were identified through medical records and video-EEG databases, and no interventions were performed as part of the study.
Adults aged 18 years and older Diagnosis of psychogenic nonepileptic seizures (PNES) confirmed by video-EEG monitoring Availability of complete video-EEG recordings capturing at least one typical event Availability of sufficient clinical and demographic data in medical records for retrospective evaluation
Exclusion Criteria:
Patients younger than 18 years Incomplete or poor-quality video-EEG recordings Absence of recorded typical PNES events during video-EEG monitoring Insufficient clinical documentation for retrospective analysis
patients with pnes underwent video eeg monitoring
Semiological cluster classification of PNES events
Classification of PNES events into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features identified during video-EEG monitoring.
Time frame: Baseline (retrospective video-EEG analysis)
pnes events
Eye closure during PNES events Hyperventilation during PNES events Abrupt onset of PNES events Abrupt termination of PNES events Hyperkinetic motor activity Presence or absence of excessive motor activity (e.g., thrashing movements). Tremor during PNES events Dystonic posturing Axial extension Axial immobility Pelvic thrusting Presence or absence of pelvic thrusting.
Time frame: baseline
Plan to share: No
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This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Tepecik Training and Research Hospital