An interventional study of Sunflower Oil and Olive Oil in Diaper Dermatitis, sponsored by Dicle University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 0 Months to 24 Months. Per ClinicalTrials.gov, last updated 2026-08-27.
Sponsored by Dicle University · Not applicable, Interventional, and Prevention
This quasi-experimental study aimed to evaluate the effects of sunflower oil and olive oil on the development of diaper dermatitis in hospitalized infants receiving antibiotic therapy. Infants aged 0-24 months were assigned to sunflower oil, olive oil, and control groups. Oils were applied to the diaper area after each diaper change. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The incidence of diaper dermatitis was compared between groups.
Diaper dermatitis is a common skin condition in infants and occurs more frequently in hospitalized infants receiving systemic antibiotics. This quasi-experimental study evaluated the preventive effects of sunflower oil and olive oil on diaper dermatitis. The study included 150 infants aged 0-24 months hospitalized and receiving antibiotic therapy. Participants were assigned to three groups: sunflower oil, olive oil, and control. In the intervention groups, oils were applied to the diaper area after each diaper change, while the control group received routine care. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The primary outcome was the incidence of diaper dermatitis. The study aimed to determine whether sunflower oil and olive oil reduce diaper dermatitis in hospitalized infants.
38 studies on the registry are indexed under Diaper Rash; 4 are open to participants now.
This study's enrollment of 150 is above the median of 92 across 28 interventional studies indexed under Diaper Rash.
Browse Diaper Rash studies →Dicle University is the lead sponsor of 28 studies on the registry; 7 are open to participants now.
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Exclusion Criteria:
Participants received sunflower oil applied to the diaper area after each diaper change during hospitalization.
Other: Sunflower Oil
Participants received olive oil applied to the diaper area after each diaper change during hospitalization.
Other: Olive Oil
Participants received routine diaper care without topical oil application.
Other: Routine Care
Sunflower oil applied to the diaper area after each diaper change during hospitalization.
Olive oil applied to the diaper area after each diaper change during hospitalization.
Routine diaper care without topical oil application during hospitalization.
Incidence of diaper dermatitis
Incidence of diaper dermatitis assessed using diaper dermatitis severity scoring system in hospitalized infants receiving sunflower oil, olive oil, or routine care.
Time frame: During hospitalization (3 days up to 7 days)
Four-grade clinical classification described by Kırçuval (2001)
Diaper dermatitis severity was assessed daily using the four-grade clinical classification described by Kırçuval (2001). Severity ranges from Grade I to Grade IV (1-4). Grade I indicates mild erythema limited to the diaper area; Grade II indicates marked erythema with lesions or desquamation limited to the diaper area; Grade III indicates marked erythema extending to the inner thighs and abdomen; and Grade IV indicates severe erythema with erosion and pustules. Higher grades indicate greater diaper dermatitis severity and therefore a worse outcome.
Time frame: During hospitalization (3-7 days)
Plan to share: No — Individual participant data will not be publicly shared due to privacy and ethical restrictions involving infant participants. De-identified data may be available from the corresponding author upon reasonable request.
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This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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