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Not yet recruitingNCT07486154QUIETUpdated Mar 20, 2026

Complex Decisions Regarding Antithrombotic Therapy: the QUIET Study

An observational study in Palliative Care, sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Not yet recruiting at 1 site in Italy. Per ClinicalTrials.gov, last updated 2026-03-20.

Sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
300
Sex
All
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Study summary

"Complex decisions regarding antithrombotic therapy: the QUIET study" is a monocentric observational study without drug intervention, conducted through the administration of a questionnaire (survey).The aim of this study is to explore, through the administration of a questionnaire (survey) consisting of hypothetical clinical cases, the approach of physicians regarding the prescription, continuation, or discontinuation of antithrombotic therapies in patients referred to Palliative Care.

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Conditions studied

  • Palliative Care

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Keywords

  • antithrombotic therapy
  • end of life
  • palliative care
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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Physicians affiliated with Italian scientific societies (SICP, SIMI, SIGG, SISET, SIAPAV) and involved in the management of antithrombotic therapy in patients referred to Palliative Care.

Inclusion criteria

  • Affiliation, as a physician, with one of the main Italian scientific societies actively involved in the management of antithrombotic therapy in patients referred to Palliative Care
  • Electronic informed consent to participate in the study.

Exclusion criteria

Exclusion Criteria:

  • Failure to complete or incomplete completion of the questionnaire.
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Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
300 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Prevalence of discontinue/continue antithrombotic therapy

    Calculation of the prevalence of physicians who would discontinue or continue antithrombotic therapy when evaluating different clinical scenarios presented to them through a survey.

    Time frame: at enrollment

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Study locations

1 site
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Registry details

Key details

Study ID
NCT07486154
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Responsible party
Pola Roberto (Prof., Fondazione Policlinico Universitario Agostino Gemelli IRCCS) — Principal investigator
First posted
Mar 20, 2026
Start date
Apr 2026 (estimated)
Primary completion
Apr 2027 (estimated)
Completion
Apr 2027 (estimated)
Last update
Mar 20, 2026

Study contacts

Roberto Pola
Contact
roberto.pola@policlinicogemelli.it
+390630157075
Rosa Talerico
Contact
rosa.talerico@unicatt.it
+390630157075

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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