An interventional study of Moon and Sun Brothers: A Community Prevention Intervention in Help-Seeking Behavior, Pre-exposure Prophylaxis Use and Condomless Sex, sponsored by San Francisco State University. Recruiting at 2 sites in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-25.
Sponsored by San Francisco State University · Not applicable, Interventional, and Prevention
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men. The main questions the study aims to answer are:
Does the intervention improve sexual risk behaviors? Does the intervention increase self-esteem and social support? Are self-esteem and social support mediators in the link between the intervention and sexual risk? Researchers will compare information from the intervention versus control participants to answer the above questions.
Participants in the intervention arm will take part in:
60 studies on the registry are indexed under Health Risk Behaviors; 17 are open to participants now.
This study's planned enrollment of 360 is above the median of 144 across 47 interventional studies indexed under Health Risk Behaviors.
Browse Health Risk Behaviors studies →San Francisco State University is the lead sponsor of 5 studies on the registry; 1 is open to participants now.
Compared within Health Risk Behaviors, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Help-Seeking Behavior. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Over the course of twelve months, study participants will participate in: 1) One day-long (8-hour) group retreat (dosage: 100%); 2) Weekly discussion groups (dosage: minimum of 50% of weekly sessions); 3) Community participation (dosage: minimum of 5 civic engagement activities; 50% of community events); and 4) Prevention counseling sessions (dosage: minimum of 1 session). Intervention participants will take part in all four components.
Behavioral: Moon and Sun Brothers: A Community Prevention Intervention
Participants in the control arm will be unexposed to the intervention components.
The is a community-based, group intervention delivered in Spanish, using a quasi-experimental design, to reduce HIV sexual risk among Hispanic immigrants who identify as gay/bisexual men or men who have sex with men (GBMSM).
Self-reported condomless anal intercourse
Time frame: From baseline to end the of intervention, at twelve months.
Self-Esteem
We will assess self-esteem using the 20-item Inner Strength Scale adapted for this study with response options and corresponding scores as follows: never (0), rarely (1), sometimes (2), often (4) and very often (4). The scores ranged from 0 to 80 with higher scores denoting higher degrees of inner strength.
Time frame: From enrollment to the end of intervention at 12 months
Social Support
We will assess social support using a 20-item questionnaire developed by Krause, measuring social embeddedness (contact with friends and family) and enacted support from others (which entail emotional, tangible and informational support). These items are scored (coding in parentheses) based on the following responses: never (0), rarely (1), sometimes (2), often (3) and very often (4). The scores range from 0-80, with higher scores denoting a higher degree of social support.
Time frame: From enrollment to the end of intervention, at 12 months.
Plan to share: Yes — De-identified Individual participant data collected as part of this intervention.
Supporting information: Study protocol, Statistical analysis plan, Analytic code
Time frame: The IPD and supporting information will be available after all specific analyses have been completed (on or about 7/31/2029), and available 36 months thereafter.
Access criteria: Researchers engaged in independent scientific research may request access to the IPD by submitting a research proposal and a statistical analysis plan. After review and approval of the proposal, a signed data sharing agreement is required before the data can be accessed.
Started Jan 2026 (actual). Primary completion is estimated for Mar 2028, 26 months after the start.
Of 36 non-industry interventional studies with no phase under Health Risk Behaviors, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 32. This study's planned 26 months is above that.
Counting every sponsor, half of 37 studies reached it within 18 months; a quarter within 5 and three quarters within 32.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
San Francisco State University