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CompletedNCT07459023scalpUpdated Mar 9, 2026

Changes in Scalp Condition After Using a Moisturizer: a Prospective Clinical Trial Using Artificial Intelligence

An interventional study of Ducray Kertyol P.S.O. Concentrate Cream, Ducray Laboratory, France in Dandruff and Seborrhoeic Dermatitis of the Scalp, sponsored by Seoul National University Bundang Hospital. Completed at 1 site in South Korea. Open to participants aged 19 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-09.

Sponsored by Seoul National University Bundang Hospital · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Jul 2025, registered Feb 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
23
Allocation
Not applicable
Ages
19 Years and older
Sex
All
01

Study summary

The goal of this clinical trial is to evaluate whether a scalp moisturizer containing celastrol and Cichorium intybus root extract can improve scalp condition in adults aged 19 years or older who require scalp moisturization due to dryness, scaling, erythema, or dandruff. The main questions it aims to answer are:

Does once-daily application of the study moisturizer improve scalp condition from baseline to week 4, as assessed by SPI-AI (Scalp Photographic Index-Artificial Intelligence)?

Does the moisturizer improve scalp biophysical parameters (erythema index, stratum corneum hydration, and transepidermal water loss) and patient-reported symptom severity over the 4-week treatment period?

Participants will:

Apply the study moisturizer once daily at bedtime to dry scalp for 4 weeks and rinse it off the following morning using their usual shampoo.

Attend study visits at baseline (week 0), week 2, and week 4 for scalp imaging, biophysical measurements, symptom questionnaires, adherence assessment, and safety monitoring.

02

Conditions studied

  • Dandruff
  • Seborrhoeic Dermatitis of the Scalp

Keywords

  • scalp discomfort
  • scalp erythema
  • scalp dryness
  • scalp scaling
  • scalp pruritus
03

In context

Lead sponsor

Seoul National University Bundang Hospital is the lead sponsor of 376 studies on the registry; 56 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age ≥19 years
  • Presence of scalp erythema, dryness, scaling, or dandruff requiring scalp moisturization

Exclusion criteria

Exclusion Criteria:

  • Active infectious scalp dermatoses
  • Use of topical or systemic therapies affecting scalp status within 4 weeks prior to enrollment or during the study period
  • Inability to comply with the study protocol
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
23 participants (actual)

Study arms

  • Active comparator
    Moisturizer

    participants applies the moisturizer once daily to the entire scalp at bedtime

    Other: Ducray Kertyol P.S.O. Concentrate Cream, Ducray Laboratory, France

Interventions

  • OtherDucray Kertyol P.S.O. Concentrate Cream, Ducray Laboratory, France

    participants applied the moisturizer once daily to the entire scalp at bedtime

06

What researchers measure

Primary outcomes

  1. SPI-AI

    Scalp Photographic Index with artificial intelligence

    Time frame: 4week

Secondary outcomes

  1. SPI-AI

    Scalp Photographic Index with artificial intelligence

    Time frame: 2week

  2. Biophysical parameter

    erythema index (arbitrary unit)

    Time frame: 2week

  3. Biophysical parameter

    erythema index (arbitrary unit)

    Time frame: 4week

  4. Biophysical parameter

    corneometer (arbitrary unit)

    Time frame: 2 week

  5. Biophysical parameter

    corneometer (arbitrary unit)

    Time frame: 4 week

  6. Biophysical parameter

    transepidermal water loss (g/m2/h)

    Time frame: 2 week

  7. Biophysical parameter

    transepidermal water loss (g/m2/h)

    Time frame: 4 week

  8. Patient-reported outcome

    visual analog scale (0-10) : higher is worse

    Time frame: 2 week

  9. Patient-reported outcome

    visual analog scale (0-10) : higher is worse

    Time frame: 4 week

07

Study locations

1 site
  • Seoul National University Bundang Hospital
    Seongnam-si, Kyeonggi, South Korea
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jul 2025 to primary completion in Dec 2025, 5 months.

How these figures are worked out, and which studies are left out of them.

Registered
Feb 26, 2026
First posted
Mar 9, 2026
StartActual
Jul 1, 2025
Primary completionActual
Dec 31, 2025
CompletionActual
Dec 31, 2025
Last update
Mar 9, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07459023
Responsible party
Bo Ri Kim (Assistant professor, Seoul National University Bundang Hospital) — Principal investigator
First posted
Mar 9, 2026
Start date
Jul 1, 2025
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025
Last update
Mar 9, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.

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