An interventional study of sterile gauze dressing in Nevus, Seborrheic Keratosis (SK) and Cyst, sponsored by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. Completed at 1 site in China. Open to participants aged 14 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-03-03.
Sponsored by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Not applicable, Interventional, and Supportive care
What is this study about? You are being invited to participate in a clinical research study because you are scheduled to undergo a facial skin surgery for your health condition. Your surgeon will perform your operation independently, and your standard surgical procedure and follow-up visits will not be changed in any way by this study.
The purpose of this research is to understand which postoperative care method is more beneficial for facial wound healing and for reducing scar formation. We aim to compare two common approaches for caring for the wound after surgery. Your participation will help doctors choose better care plans for future patients.
What will happen in this study?
If you agree to participate, you will be randomly assigned (like drawing lots) to one of two groups:
Group A (Early Exposure Group): About 6 hours after your surgery, the doctor will remove the sterile gauze covering your wound. After this, you will need to keep the wound area clean and dry, and you will not use a gauze dressing to cover it.
Group B (Continuous Coverage Group): After surgery, your wound will continue to be covered with sterile gauze. The doctor or nurse will change the dressing for you regularly until the sutures are removed around 7 days after surgery, or until it is decided to stop based on how the wound is healing.
What will I need to do differently?
Apart from the assigned wound care method described above, participating in this study involves only the following additions to your regular care:
Before Surgery: You will be asked to fill out a simple questionnaire about your skin and undergo a quick, non-invasive skin measurement.
During Follow-up Visits: You will be asked to fill out questionnaires and allow the study doctor to take photographs of your surgical area. These photos will be used only for analysis and record-keeping in this study.
Your total time commitment for these extra activities is minimal. Participation is entirely voluntary, and your decision will not affect the quality of your medical care.
Key Information:
Your surgeon decides your operation. This study only involves postoperative wound care.
Random Assignment: You cannot choose your group; it is decided randomly by a computer.
Privacy: Your personal information and study data (including photos) will be kept strictly confidential and used only for this research.
Potential Benefit: You may not benefit directly, but your participation will contribute to medical knowledge.
Potential Risks: The risks are considered minimal and are similar to those of standard wound care. The study doctor will monitor your healing closely.
You will receive a detailed informed consent form with more information. Please discuss any questions you have with the research team before deciding.
47 studies on the registry are indexed under Nevus; 9 are open to participants now.
This study's enrollment of 144 is above the median of 100 across 19 interventional studies indexed under Nevus.
Browse Nevus studies →Union Hospital, Tongji Medical College, Huazhong University of Science and Technology is the lead sponsor of 181 studies on the registry; 144 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The diagnosis was confirmed by looking at a sample under a microscope: tissue from a biopsy or surgery (histology), or cells from a fluid or needle sample (cytology).
Your pathology report is the document that shows this.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Histologically or cytologically confirmed
The diagnosis was confirmed by looking at a sample under a microscope: tissue from a biopsy or surgery (histology), or cells from a fluid or needle sample (cytology).
Your pathology report is the document that shows this.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Six hours after surgery, the sterile gauze dressing covering the surgical area will be removed. From then on, the wound will be disinfected once daily using a 0.5% povidone-iodine solution. The wound should be kept clean and dry, with no further dressing coverage or application of other topical medications, until the sutures are removed on the seventh postoperative day.
Procedure: sterile gauze dressing
On the second postoperative day, remove the initial dressing, disinfect the wound with 0.5% povidone-iodine solution (without using other topical medications), and then cover it with a sterile gauze dressing. Thereafter, repeat the dressing change every 48 hours-meaning the wound should remain continuously covered-until the sutures are removed on the seventh postoperative day.
Six hours after surgery, the sterile gauze dressing covering the surgical area will be removed. From then on, the wound will be disinfected once daily using a 0.5% povidone-iodine solution. The wound should be kept clean and dry, with no further dressing coverage or application of other topical medications, until the sutures are removed on the seventh postoperative day.
Incidence of Postoperative Edema
Assessed by direct clinical examination. Unit: % of participants with the presence of edema.
Time frame: 7-day follow-up
Incidence of Postoperative Wound Suppuration
Assessed by direct clinical examination. Unit: % of participants with the presence of wound suppuration.
Time frame: 7-day follow-up
Incidence of Postoperative Peri-wound Erythema
Assessed by direct clinical examination. Unit: % of participants with the presence of peri-wound erythema.
Time frame: 7-day follow-up
Incidence of Postoperative Wound Tenderness
Assessed by direct clinical examination. Unit: % of participants with the presence of wound tenderness.
Time frame: 7-day follow-up
Incidence of Postoperative Hemorrhage
Assessed by direct clinical examination. Unit: % of participants with the presence of postoperative hemorrhage.
Time frame: 7-day follow-up
Incidence of Postoperative Ecchymosis
Assessed by direct clinical examination. Unit: % of participants with the presence of wound ecchymosis.
Time frame: 7-day follow-up
Patient and Observer Scar Assessment Scale version 2.0 (POSAS 2.0)
This scale comprises two separate subscales: the Observer Scar Assessment Scale (completed by the clinician) and the Patient Scar Assessment Scale (completed by the participant). The Observer Scale evaluates six items (vascularity, pigmentation, thickness, relief, pliability, and surface area) on a scale from 1 ("like normal skin") to 10 ("the worst scar imaginable"), with a total score ranging from 6 (best) to 60 (worst). The Patient Scale evaluates six items (pain, itching, color, stiffness, thickness, and irregularity) on a scale from 1 ("no, not at all") to 10 ("yes, very much"), with a total score also ranging from 6 (best) to 60 (worst). For both subscales, a higher score indicates a worse scar quality.
Time frame: 3-month follow-up
modified Stony Brook Scar Evaluation Scale (mSBSES)
Evaluations were independently performed by two clinicians who were blinded to group allocation. The scale comprises four items: scar width, height, color, and suture marks. Each item is scored from 0 to 2 points, where a score of 2 represents the closest resemblance to normal skin, and 0 represents the worst appearance. The total score ranges from 0 to 8, with a higher score indicating a more ideal scar appearance.
Time frame: 3-month follow-up
Skindex-16
On the seventh postoperative day, the Skindex-16 dermatology-specific quality of life questionnaire will be used to assess the patient's disease-specific quality of life over the past week. This scale consists of a total of 16 items and provides a comprehensive evaluation of the impact of dermatological conditions on the patient's recent life from three dimensions: emotions, functioning, and symptoms. It is particularly suitable for assessing the quality of life in patients with mild skin lesions.
Time frame: 7-day follow-up
Ran from Jun 2025 to primary completion in Jan 2026, 7 months.
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This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology →