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RecruitingNCT07426965Updated Feb 23, 2026

Stroke Hemiplegic Shoulder Pain: Ultrasound Findings and VAS (Cross-Sectional)

An observational study in Hemiplegic Shoulder Pain, sponsored by Ankara Etlik City Hospital. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-02-23.

Sponsored by Ankara Etlik City Hospital · Observational

From the registry’s dates

  • Started Feb 2026; still recruiting 7 months later.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
100
Ages
18 Years to 75 Years
Sex
All
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Study summary

Hemiplegic shoulder pain is a frequent complication after stroke and may be associated with structural abnormalities detectable by musculoskeletal ultrasound. This prospective cross-sectional observational study aims to evaluate the relationship between shoulder ultrasound abnormality score and pain severity in patients with post-stroke hemiplegic shoulder pain. Pain severity will be assessed using the Visual Analog Scale (VAS) for rest, movement, and night pain. Shoulder ultrasound will be performed using a standardized scoring system to quantify structural abnormalities. The primary objective is to investigate whether ultrasound abnormality burden is associated with pain severity in different clinical conditions (rest, exercise, and night).

Read the detailed description

Hemiplegic shoulder pain is a common complication after stroke and may negatively affect rehabilitation outcomes. Structural abnormalities such as rotator cuff pathology, biceps tendon disorders, bursitis, adhesive capsulitis, and glenohumeral subluxation can be evaluated using musculoskeletal ultrasound.

This prospective cross-sectional observational study aims to investigate the relationship between shoulder ultrasound abnormality score and pain severity in patients with post-stroke hemiplegic shoulder pain. Adult stroke patients with hemiplegic shoulder pain will be evaluated at admission.

Pain severity will be assessed using the Visual Analog Scale (VAS) separately for rest, movement, and night pain. Shoulder ultrasound will be performed using a standardized protocol, and a total ultrasound abnormality score will be calculated.

The primary objective is to evaluate the association between ultrasound abnormality score and pain severity. Secondary analyses will assess the relationship between specific ultrasound findings and pain severity.

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Conditions studied

  • Hemiplegic Shoulder Pain

Keywords

  • Visual Analog Scale
  • Hemiplegic Shoulder Pain
  • Ultrasound
03

In context

Lead sponsor

Ankara Etlik City Hospital is the lead sponsor of 166 studies on the registry; 75 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients with stroke and hemiplegic shoulder pain who are admitted to the physical medicine and rehabilitation clinic of Ankara Etlik City Hospital will be included. Eligible patients are between 18 and 75 years of age and within 2 weeks to 6 months after stroke. All participants will undergo clinical assessment and shoulder ultrasound examination at admission.

Inclusion criteria

  1. Being between 18-75 years of age
  2. Patients with a history of stroke within the last 2 weeks to 6 months
  3. Patients with shoulder pain on the hemiplegic side
  4. Mini-mental status test score >25

Exclusion criteria

Exclusion Criteria:

  1. Motor aphasic patient group
  2. Patients with a history of previous surgery on the hemiplegic shoulder for any reason
  3. Those with other diseases that can explain the shoulder pain
  4. Those with neurodegenerative diseases that cause impairment in cognitive functions, such as dementia
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No

Groups and cohorts

  • Post-stroke Hemiplegic Shoulder Pain Patients

    Adult stroke patients with hemiplegic shoulder pain who are evaluated at admission. Pain severity is assessed using the Visual Analog Scale (VAS) for rest, movement, and night pain. Shoulder ultrasound is performed using a standardized protocol, and an ultrasound abnormality score is calculated to evaluate the relationship between structural abnormalities and pain severity.

06

What researchers measure

Primary outcomes

  1. Association between shoulder ultrasound abnormality score and pain severity

    Relationship between total shoulder ultrasound abnormality score and Visual Analog Scale (VAS) pain scores (rest, movement, and night pain) assessed at admission.

    Time frame: At admission (single assessment on the same day as ultrasound)

07

Study locations

1 of 1 sites recruiting
  • Ankara Etlik Şehir Hastanesi
    Ankara, Turkey (Türkiye)
    • ayşe naz kalem, md · Contact · kalemnaz@gmail.com · +905333626947
    • aliye aygün, md · Contact · aliyeaygunn@hotmail.com · +905454764771
    • nihal tezel, Associate Professor · Principal investigator
    • aliye aygün, MD,Resident Physician · Sub investigator
    • ayşe naz kalem, MD · Sub investigator
    Recruiting
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References and documents

Publications

  • Pong YP, Wang LY, Huang YC, Leong CP, Liaw MY, Chen HY. Sonography and physical findings in stroke patients with hemiplegic shoulders: a longitudinal study. J Rehabil Med. 2012 Jun;44(7):553-7. doi: 10.2340/16501977-0987. PubMed 22674236 ↗
  • Huang SW, Liu SY, Tang HW, Wei TS, Wang WT, Yang CP. Relationship between severity of shoulder subluxation and soft-tissue injury in hemiplegic stroke patients. J Rehabil Med. 2012 Sep;44(9):733-9. doi: 10.2340/16501977-1026. PubMed 22854896 ↗

Related links

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07426965
Lead sponsor
Ankara Etlik City Hospital
Responsible party
Ayse Naz Kalem (MD, Ankara Etlik City Hospital) — Principal investigator
First posted
Feb 23, 2026
Start date
Feb 17, 2026
Primary completion
Aug 2026 (estimated)
Completion
Sep 2026 (estimated)
Last update
Feb 23, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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