CClinicalTrials.gg
CompletedNCT07403292Updated Feb 11, 2026

Comparative Effects of McGill and McKenzie Exercises in Low Back Pain

An interventional study of McGill Exercises and McKenzie Exercises in Chronic Mechanical Low Back Pain, sponsored by Riphah International University. Completed at 1 site in Pakistan. Open to participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-02-11.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year after the study started (first participant enrolled Jan 2025, registered Feb 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
57
Allocation
Randomized
Ages
20 Years to 40 Years
Sex
All
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Study summary

The study was conducted to determine the comparative effects of McGill and McKenzie exercises on pain, range of motion and disability in patients with chronic mechanical low back pain.

02

Conditions studied

  • Chronic Mechanical Low Back Pain

Browse trials for

Keywords

  • McGill exercises
  • McKenzie Exercises
  • pain
  • range of motion
  • disability
  • chronic mechanical low back pain
03

In context

Pain

2,219 studies on the registry are indexed under Pain; 915 are open to participants now.

This study's enrollment of 57 is below the median of 70 across 1,901 interventional studies indexed under Pain.

Browse Pain studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Both genders.
  • Patients between 20-40 years.
  • At least 6 months of history of chronic mechanical low back pain.
  • Negative Lasegue's Test.
  • Negative Slump Test.
  • Patient presenting with NPRS values of above 1 and equal to or less than 6.
  • ODI score from 5-24, with the patient showing minimal to moderate disability.
  • Patient showing restricted lumbar range of motion in any direction of flexion, extension, and lateral flexion.
  • Participants must demonstrate an extension directional preference during clinical examination (For the safety purpose of the patients)

Exclusion criteria

Exclusion Criteria:

  • Lumbar radiculopathy.

    • Previous record showing Trauma or accident.
    • Any previous surgical record of Lumbar Spine Surgery.
    • Acute or Subacute low back pain.
    • History of spinal osteoporosis.
    • Vertebral Fractures.
    • Tumors and active infections.
    • Diagnosed psychological disorders.
    • Any spinal deformity
    • Participants who do not show directional preference towards extension
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
57 participants (actual)

Study arms

  • Experimental
    McGill Exercises

    Other: McGill Exercises · Other: Standardized Physiotherapy Treatment

  • Active comparator
    McKenzie Exercises

    Other: McKenzie Exercises · Other: Standardized Physiotherapy Treatment

Interventions

  • OtherMcGill Exercises

    McGill Big three exercises for 10 repetitions and 5-10 seconds of hold initially. Progression was tailored as per the patient's requirements and stamina. * Standardized physiotherapy treatment at the first session. * McGill curl-up * Isometric horizontal side support, either with support on knees or on foot, according to patient stamina. * Single leg extension holds on hands and knees, also known as McGill Birddog, either with or without raising the contralateral arm as per patient stamina.

  • OtherMcKenzie Exercises

    McKenzie extension exercise plan (EEP) for 10 repetitions and 5-10 seconds of hold initially. Progression was tailored as per the patient's requirements and symptoms * Standardized physiotherapy treatment at the first session. * Lying face down in extension on elbows. * Full press up. * Extension in standing.

  • OtherStandardized Physiotherapy Treatment

    * Electrical Heating Pad was applied for 10 minutes. * TENS was applied (low frequency) for 10 minutes. * Posterior to Anterior Glides of Lumbar Spine in Maitland Grade-III, with 4 sets and 4 repetitions each. The patient will be in a prone position.

06

What researchers measure

Primary outcomes

  1. Numeric Pain Rating Scale

    Pain intensity was measured using the Numeric Pain Rating Scale which is abbreviated as NPRS. In this tool, individuals score their pain levels on a scale from 0 to 10. When a participant selects 0, it means they had no pain. On the other hand, if it is 10, the participant must be going through the worst pain imaginable.

    Time frame: From enrollment to the end of the treatment at 6 weeks

  2. Oswestry Disability Index

    The Oswestry Disability Index (ODI) is a questionnaire that participants fill themselves based on self-reporting. It is based on disability caused by low back pain. Pynsent in Oswestry, England, introduced it in 1980. It has become one of the most widely used and trusted tools for evaluating disability related to back pain.

    Time frame: From enrollment to the end of the treatment at 6 weeks.

  3. Lumbar Range of Motion

    Different instruments are used in physiotherapy to measure the range of motions, like a goniometer and an inclinometer. An inclinometer is used to measure spinal ROM.

    Time frame: From enrollment to the end of the 6 weeks

Secondary outcomes

  1. Lumbar Flexion

    Measured by inclinometer.

    Time frame: From enrollment to end of the treatment at 6 weeks.

  2. Lumbar Extension

    Measured by Inclinometer

    Time frame: From enrollment to end of the treatment by 6 weeks.

  3. Lumbar Right Lateral Flexion

    Measured by Inclinometer

    Time frame: From enrollment to the end of 6 weeks

  4. Lumbar Left Lateral Flexion

    Measured by using Inclinometer

    Time frame: From enrollment to end of the treatment by 6 weeks.

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Study locations

1 site
  • Naseer Hospital
    Lahore, Punjab Province, Pakistan
08

References and documents

Publications

  • Sabourin S, Tram J, Sheldon BL, Pilitsis JG. Defining minimal clinically important differences in pain and disability outcomes of patients with chronic pain treated with spinal cord stimulation. J Neurosurg Spine. 2021 Jun 4;35(2):243-250. doi: 10.3171/2020.11.SPINE201431. Print 2021 Aug 1. PubMed 34087802 ↗
  • Young I, Dunning J, Escaloni J, Maselli F, Prall J, Mourad F, Fernandez-de-Las-Penas C. Reliability, construct validity, responsiveness and minimum clinically important difference of the numeric pain rating scale and shoulder pain and disability index in patients with subacromial pain syndrome. Musculoskelet Sci Pract. 2025 Oct;79:103372. doi: 10.1016/j.msksp.2025.103372. Epub 2025 Jun 28. PubMed 40614306 ↗
  • na Fisioterapia MM. Methods & protocols.
  • McGill SM. Low back exercises: evidence for improving exercise regimens. Phys Ther. 1998 Jul;78(7):754-65. doi: 10.1093/ptj/78.7.754. PubMed 9672547 ↗
  • Saur PM, Ensink FB, Frese K, Seeger D, Hildebrandt J. Lumbar range of motion: reliability and validity of the inclinometer technique in the clinical measurement of trunk flexibility. Spine (Phila Pa 1976). 1996 Jun 1;21(11):1332-8. doi: 10.1097/00007632-199606010-00011. PubMed 8725925 ↗
  • Grotle M, Brox JI, Vollestad NK. Cross-cultural adaptation of the Norwegian versions of the Roland-Morris Disability Questionnaire and the Oswestry Disability Index. J Rehabil Med. 2003 Sep;35(5):241-7. doi: 10.1080/16501970306094. PubMed 14582557 ↗
  • Childs JD, Piva SR, Fritz JM. Responsiveness of the numeric pain rating scale in patients with low back pain. Spine (Phila Pa 1976). 2005 Jun 1;30(11):1331-4. doi: 10.1097/01.brs.0000164099.92112.29. PubMed 15928561 ↗
  • Alhakami AM, Davis S, Qasheesh M, Shaphe A, Chahal A. Effects of McKenzie and stabilization exercises in reducing pain intensity and functional disability in individuals with nonspecific chronic low back pain: a systematic review. J Phys Ther Sci. 2019 Jul;31(7):590-597. doi: 10.1589/jpts.31.590. Epub 2019 Jul 9. PubMed 31417227 ↗
  • Nayyab I, Ghous M, Shakil Ur Rehman S, Yaqoob I. The effects of an exercise programme for core muscle strengthening in patients with low back pain after Caesarian-section: A single blind randomized controlled trial. J Pak Med Assoc. 2021 May;71(5):1319-1325. doi: 10.47391/JPMA.596. PubMed 34091607 ↗
  • Ahmed R, Shakil-Ur-Rehman S, Sibtain F. Comparison between Specific Lumber Mobilization and Core-Stability Exercises with Core-Stability Exercises Alone in Mechanical low back pain. Pak J Med Sci. 2014 Jan;30(1):157-60. doi: 10.12669/pjms.301.4424. PubMed 24639852 ↗
  • Golzar J, Noor S, Tajik O. Convenience sampling. International Journal of Education & Language Studies. 2022;1(2):72-7.
  • Javaherian M, Bashardoust TS, ATTARBASHI MB, KESHTKAR A, Azizi M. Immediate effects of Maitland mobilization and Mulligan techniques on flexion and extension range of motion in patients with chronic nonspecific low back pain: a randomized pilot study. 2017.
  • Waqqar S, Shakil-Ur-Rehman S, Ahmad S. McKenzie treatment versus mulligan sustained natural apophyseal glides for chronic mechanical low back pain. Pak J Med Sci. 2016 Mar-Apr;32(2):476-9. doi: 10.12669/pjms.322.9127. PubMed 27182265 ↗
  • Kleine-Borgmann J, Schmidt K, Hellmann A, Bingel U. Effects of open-label placebo on pain, functional disability, and spine mobility in patients with chronic back pain: a randomized controlled trial. Pain. 2019 Dec;160(12):2891-2897. doi: 10.1097/j.pain.0000000000001683. PubMed 31479068 ↗
  • Ghasemi G, Goharjoo M, Faizi M. Effects of conventional core stability and core stability suspension exercises on multifidus muscle endurance, pain and quality of life in people with nonspecific chronic low back pain. Jundishapur Scientific Medical Journal. 2020;18(6):571-84.
  • Hernándeza DMG, Pérez SMO, Ardón FB, Núñez CLT, Moreno JGO. Effectiveness of neurodynamic mobilization and MCGILL-type strengthening exercises in patients with piriformis syndrome: study protocol for a randomized controlled trial. Physical Rehabilitation and Recreational Health Technologies. 2024;9(3):188-200.
  • Purushothaman S, Gayathri K, Thiyagarajan A, Vardhini CI, Babu LH, Nainar M. Clinical Evaluation of the McGill Stabilization Exercise Program for Chronic Nonspecific Low Back Pain: Insights from Case Studies. Journal of Society of Indian Physiotherapists. 2024;8(2):144-8.
  • Baghani P, Naserpour N, Piri H. Supervised Group Exercise Therapy Versus Home-based Exercise Therapy: The Effect of McGill Exercises on Pain, Disability and Trunk Stability in Middle-aged Women With Non-specific Chronic Low Back Pain. Physical Treatments-Specific Physical Therapy Journal. 2023;13(2):127-34.
  • Aqil F, Iqbal MA, Karim S, Iqbal MU, Akram MJ, Mehreen Z, et al. Comparison of Mckenzie approach versus Lumbar Stabilization Exercises in the treatment of chronic low back pain. Rehman Journal of Health Sciences. 2021;3(1):24-31.
  • Bose G, Gohill D. Effect of Mckenzie Therapy and Lumbar Strengthening Program in Lumbar Spine Derangement Syndrome 1. European Journal of Pharmaceutical and Medical Research. 2018;5(3):160-4.
  • Namnaqani FI, Mashabi AS, Yaseen KM, Alshehri MA. The effectiveness of McKenzie method compared to manual therapy for treating chronic low back pain: a systematic review. J Musculoskelet Neuronal Interact. 2019 Dec 1;19(4):492-499. PubMed 31789300 ↗
  • Lam OT, Strenger DM, Chan-Fee M, Pham PT, Preuss RA, Robbins SM. Effectiveness of the McKenzie Method of Mechanical Diagnosis and Therapy for Treating Low Back Pain: Literature Review With Meta-analysis. J Orthop Sports Phys Ther. 2018 Jun;48(6):476-490. doi: 10.2519/jospt.2018.7562. Epub 2018 Mar 30. PubMed 29602304 ↗
  • Ghorbanpour A, Azghani MR, Taghipour M, Salahzadeh Z, Ghaderi F, Oskouei AE. Effects of McGill stabilization exercises and conventional physiotherapy on pain, functional disability and active back range of motion in patients with chronic non-specific low back pain. J Phys Ther Sci. 2018 Apr;30(4):481-485. doi: 10.1589/jpts.30.481. Epub 2018 Apr 13. PubMed 29706690 ↗
  • Olaoye MI, Okonji R, Ademoyegun A, Gebrye T, Yeowell G, Fatoye F, Mbada C. Biochemical and clinical effects of McKenzie therapy versus muscle endurance exercises in chronic low-back pain. Arch Physiother. 2025 Sep 17;15:229-249. doi: 10.33393/aop.2025.3331. eCollection 2025 Jan-Dec. PubMed 40977828 ↗
  • Calatayud J, Escriche-Escuder A, Cruz-Montecinos C, Andersen LL, Perez-Alenda S, Aiguade R, Casana J. Tolerability and Muscle Activity of Core Muscle Exercises in Chronic Low-back Pain. Int J Environ Res Public Health. 2019 Sep 20;16(19):3509. doi: 10.3390/ijerph16193509. PubMed 31547140 ↗
  • Langevin HM, Sherman KJ. Pathophysiological model for chronic low back pain integrating connective tissue and nervous system mechanisms. Med Hypotheses. 2007;68(1):74-80. doi: 10.1016/j.mehy.2006.06.033. Epub 2006 Aug 21. PubMed 16919887 ↗
  • Casiano VE, Sarwan G, Dydyk AM, Varacallo MA. Back pain. StatPearls [Internet]: StatPearls Publishing; 2023.
  • Mohd Isa IL, Teoh SL, Mohd Nor NH, Mokhtar SA. Discogenic Low Back Pain: Anatomy, Pathophysiology and Treatments of Intervertebral Disc Degeneration. Int J Mol Sci. 2022 Dec 22;24(1):208. doi: 10.3390/ijms24010208. PubMed 36613651 ↗
  • Li W, Gong Y, Liu J, Guo Y, Tang H, Qin S, Zhao Y, Wang S, Xu Z, Chen B. Peripheral and Central Pathological Mechanisms of Chronic Low Back Pain: A Narrative Review. J Pain Res. 2021 May 27;14:1483-1494. doi: 10.2147/JPR.S306280. eCollection 2021. PubMed 34079363 ↗
  • Borenstein D. Mechanical low back pain--a rheumatologist's view. Nat Rev Rheumatol. 2013 Nov;9(11):643-53. doi: 10.1038/nrrheum.2013.133. Epub 2013 Sep 10. PubMed 24018549 ↗
  • Will JS, Bury DC, Miller JA. Mechanical Low Back Pain. Am Fam Physician. 2018 Oct 1;98(7):421-428. PubMed 30252425 ↗
  • Hnatesen D, Pavic R, Rados I, Dimitrijevic I, Budrovac D, Cebohin M, Gusar I. Quality of Life and Mental Distress in Patients with Chronic Low Back Pain: A Cross-Sectional Study. Int J Environ Res Public Health. 2022 Aug 26;19(17):10657. doi: 10.3390/ijerph191710657. PubMed 36078372 ↗
  • Osagie RO, Tufa I, Angarita-Fonseca A, Page MG, Lacasse A, Stone LS, Rainville P, Roy M, Tetreault P, Fortin M, Leonard G, Masse-Alarie H, Roy JS, Grant AV, Meloto CB; Quebec Back Pain Consortium. Impact of different acute low back pain definitions on the predictors and on the risk of transition to chronic low back pain: a prospective longitudinal cohort study. Pain. 2025 Nov 1;166(11):e577-e589. doi: 10.1097/j.pain.0000000000003669. Epub 2025 Jun 11. PubMed 40663110 ↗
  • Nieminen LK, Pyysalo LM, Kankaanpaa MJ. Prognostic factors for pain chronicity in low back pain: a systematic review. Pain Rep. 2021 Apr 1;6(1):e919. doi: 10.1097/PR9.0000000000000919. eCollection 2021. PubMed 33981936 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 11, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07403292
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Feb 11, 2026
Start date
Jan 13, 2025
Primary completion
May 31, 2025
Completion
Nov 30, 2025
Last update
Feb 11, 2026

Study contacts

Shakil ur Rehman, Ph.D
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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