An interventional study of Calligraphic Handwriting Exercise Program in PARKINSON DISEASE (Disorder), sponsored by Sara Llamas Velasco. Completed at 1 site in Spain. Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-02-10.
Sponsored by Sara Llamas Velasco · Not applicable, Interventional, and Treatment
Parkinson's disease is a progressive neurodegenerative disorder with no curative treatment currently available. Its symptoms lead to increasing limitations in daily activities, with impairments in manual dexterity being particularly relevant. Handwriting difficulties are common in patients with Parkinson's disease; however, it remains unclear whether a rehabilitation program based on handwriting exercises can improve overall manual dexterity and daily functioning.
This randomized, single-blind controlled trial aims to evaluate the effects of a 12-week home-based calligraphic handwriting exercise program on manual dexterity in patients with Parkinson's disease. Participants will be recruited from the Movement Disorders Clinic of Hospital 12 de Octubre (Madrid, Spain) and randomly assigned to either an intervention group or a control group.
Manual dexterity will be primarily assessed using the Purdue Pegboard Test across scheduled study visits. Secondary outcomes will include measures of dexterity related to activities of daily living, quality of life, and motor function.
4,487 studies on the registry are indexed under Parkinson Disease; 1,082 are open to participants now.
This study's enrollment of 53 is above the median of 40 across 3,294 interventional studies indexed under Parkinson Disease.
Browse Parkinson Disease studies →This is the only study on the registry with Sara Llamas Velasco as lead sponsor.
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EXCLUSION CRITERIA:
Severe tremor or severe dyskinesias affecting the dominant hand, defined as:
Participants assigned to this group will perform a structured home-based calligraphic handwriting exercise program designed to improve fine motor control and manual dexterity over a 12-week period.
Behavioral: Calligraphic Handwriting Exercise Program
Participants assigned to this group will receive usual clinical care and will not participate in the calligraphic handwriting exercise program during the study period.
A structured home-based calligraphic handwriting exercise program designed to train fine motor control and manual dexterity. Participants perform predefined handwriting exercises regularly over a 12-week period using provided written materials.
Change in Manual Dexterity
Manual dexterity will be assessed using the Purdue Pegboard Test. The primary outcome will be the change in Purdue Pegboard Test score from baseline across scheduled study visits.
Time frame: Baseline and up to 12 weeks
Plan to share: No
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This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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