ClinicalTrials.gg
Enrolling by invitationNCT07399119Updated Feb 10, 2026

The Study Examined the Acute Effects of Wim Hof on Aerobic Training and Cardiodynamics.

An interventional study of aerobic exercise where it included walking/ jogging with a controlled speed by the participant and Wim Hof Breathing Method in Respiratory Abnormality, Pulmonary and Exercise Training, sponsored by Cairo University. Enrolling by invitation at 1 site in Lebanon. Open to participants aged 18 Years to 25 Years. Per ClinicalTrials.gov, last updated 2026-02-10.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Feb 2026, 9 months ago, but the record still lists the study as enrolling by invitation.
  • Registered 7 months after the study started (first participant enrolled Jun 2025, registered Jan 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years to 25 Years
Sex
All
01

Study summary

Researchers will split the sixty healthy smokers in half. Thirty people will serve as a control group and will be asked to walk or jog at a controlled pace for twelve minutes as part of an aerobic exercise program. Separately, 30 people participated in an aerobic exercise session that lasted 12 minutes and involved walking or running at a pace that the participants themselves controlled. WHBM will be done both prior to and subsequent to physical activity. To determine how WHBM affects the experimental group's pre- and post-WHBM heart rates, SpO2, blood pressure, and VO2 max, this study will be conducted.

Read the detailed description

The study will be a randomized single blinded control trial, sixty healthy smokers will be divided into two groups. a control group of 30 participants will performing a 12-minute aerobic exercise where it included walking/ jogging with a controlled speed by the participant. Another experimental group of 30 participants also, performing a 12-minute aerobic exercise where it included walking/ jogging with a controlled speed by the participant. WHBM will be performed before and after exercises. It will be done to assess the effect of WHBM on heart rate, SpO2, blood pressure and VO2 max that will be monitored before and after WHBM in the experimental group. In addition, Performance will be assessed by observing the difference in distance covered before and after doing the WHBM. Heart rate and SpO2 will be measured using a finger pulse oximeter (Medical Rossmax). Blood pressure will be measured using a sphygmomanometer and VO2 max will be measured using the cooper's test formula in kilometers: "VO2 max = (22.351 x distance in Km) - 11.288"

02

Conditions studied

  • Respiratory Abnormality
  • Pulmonary
  • Exercise Training

Keywords

  • wim hoff
  • aerobic
03

In context

Lead sponsor

Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 25 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Males and females.
  • Age range between 18 and 25 years.
  • Adults who are healthy

Exclusion criteria

Exclusion Criteria:

If they had:

  • Any systemic disorders.
  • Musculoskeletal, neuromuscular, or chronic respiratory conditions.
  • Females were menstruating
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Sequential assignment
Masking
None (open label)
Enrollment
60 participants (estimated)

Study arms

  • Active comparator
    CONTROL

    Researchers took the first measurement at t=0 minutes after 5 minutes of their arrival to allow them to rest. The measurements included heart rate and SpO2 using an oximeter (Medical Rossmax) and blood pressure using a sphygmomanometer. Then they were asked to perform a 12-minute walk/jog with speed controlled by them and incline = 1. At 4 and 8 minutes, the speed was reduced to 2.0 on the treadmill, and vitals were taken again. At t= 12 minutes we stopped the treadmill, recorded the distance covered, and proceeded to measure the heart rate. SpO2, blood pressure, and VO2max were calculated using the Cooper's test formula (Alvero-Cruz et al., 2017). Participants were asked to rest for 4 minutes, and then another measurement of the vital signs (heart rate, SpO2, and blood pressure) was taken before they were dismissed.

    Other: aerobic exercise where it included walking/ jogging with a controlled speed by the participant

  • Experimental
    wim hof breathing exercises

    applying breathing interventions

    Other: aerobic exercise where it included walking/ jogging with a controlled speed by the participant · Other: Wim Hof Breathing Method

Interventions

  • Otheraerobic exercise where it included walking/ jogging with a controlled speed by the participant

    participants were asked to listen attentively to the given instruction using noise cancelling headphones for the given instructions. For 11 minutes, an audio for Wim Hof breathing method that is as follow. * Take a strong inhalation through the nose. * Let out a relaxed exhalation through the mouth. * Repeat for 30 breaths. * On the 30th breath, exhale and hold your breath for 30 seconds in the first round then 1 minute in the 2nd round and 1 and a half minutes for the 3rd round. * Take a deep breath in after the previous hold then hold it in for 15 seconds in the 3 rounds. * Let your breathing return to normal. These steps were repeated for 3 rounds. And participants were allowed to let go of their held breath and hold it again if they couldn't keep holding it for the asked time in the audio

  • OtherWim Hof Breathing Method

    participants were asked to listen attentively to the given instruction using noise cancelling headphones for the given instructions. For 11 minutes, an audio for Wim Hof breathing method that is as follow. * Take a strong inhalation through the nose. * Let out a relaxed exhalation through the mouth. * Repeat for 30 breaths. * On the 30th breath, exhale and hold your breath for 30 seconds in the first round then 1 minute in the 2nd round and 1 and a half minutes for the 3rd round. * Take a deep breath in after the previous hold then hold it in for 15 seconds in the 3 rounds. * Let your breathing return to normal. These steps were repeated for 3 rounds. And participants were allowed to let go of their held breath and hold it again if they couldn't keep holding it for the asked time in the audio

06

What researchers measure

Primary outcomes

  1. HEART RATE

    The number of heartbeats in a minute

    Time frame: 12 weeks

  2. Vo2 max

    oxygen consumption

    Time frame: 12 weeks

07

Study locations

1 site
  • BAU
    Beirut, Tariq EL Jedida 11-5020, Lebanon
08

References and documents

Related links

Individual participant data

Plan to share: Yes — measured data

Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report, Analytic code

Time frame: 5 months

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07399119
Lead sponsor
Cairo University
Responsible party
Khaled Takey Ahmed (Khaled Takey Ahmed - Associateprofessor, Cairo University) — Principal investigator
First posted
Feb 10, 2026
Start date
Jun 10, 2025
Primary completion
Feb 2026 (estimated)
Completion
Feb 2026 (estimated)
Last update
Feb 10, 2026

Study contacts

rami L abbass, professor
study director · BAU

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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