An interventional study of Relaxing aroma and state of stress/calm in To Evaluate the Main Effects of Varying Auditory Stimuli and To Evaluate the Main Effects of Varying Olfactory Stimuli, sponsored by Universidad de Zaragoza. Not yet recruiting. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-10.
Sponsored by Universidad de Zaragoza · Not applicable, Interventional, and Treatment
This study explicitly tests a multisensory virtual reality experience that combines visual, auditory, and olfactory channels to modulate the stress response in young adults. In addition to visual and auditory stimulation, the study also assesses whether a relaxing olfactory stimulus attenuates this effect. The environment and task remain constant (constant visuals); auditory and olfactory elements are varied. Objective. To evaluate the main effects of varying auditory and olfactory stimuli, as well as their interaction, on variables related to the performance of a quiz-type task in virtual reality.
Universidad de Zaragoza is the lead sponsor of 111 studies on the registry; 18 are open to participants now.
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Control Group
Experimental Group
Other: Relaxing aroma and state of stress/calm
A 2×2 randomized design is used. The Aroma condition is between subjects (relaxing aroma vs. no aroma) (experimental group and control group). The Mode condition is within each group and consists of two blocks: Stress and Calm. The order of the blocks is counterbalanced (Stress-Calm/Calm-Stress): half of the participants experience Stress first and then Calm, and the other half in the reverse order.
NASA Task Load Index
This test measures perceived mental workload. It has the following dimensions: Mental demand, effort, physical demand, performance, time constraints, and frustration level. Scoring interpretation: Higher scores for mental demand, effort, physical demand, time constraints, and frustration level indicate a greater workload/demand. Higher performance indicates a better experience. Reference: S. G. Hart y L. E. Staveland, "Development of NASA-TLX (Task Load Index): Results of Empirical and Theoretical Research", en Advances in Psychology, vol. 52, North-Holland, 1988, pp. 139-183. doi: 10.1016/S0166-4115(08)62386-9.
Time frame: From enrollment to the end of treatment at 2 weeks
Short Stress State Questionnaire (SSSQ)
Test to measure stress levels. It has three dimensions: engagement, anxiety, and worry. Scoring interpretation: * Higher score in anxiety/worry -\> worse (more stress) * Higher score in engagement -\> better (more involvement/functional activation) Reference: W. S. Helton y K. Näswall, "Short Stress State Questionnaire", Eur. J. Psychol. Assess., vol. 31, n.o 1, pp. 20-30, jun. 2015, doi: 10.1027/1015-5759/a000200.
Time frame: From enrollment to the end of treatment at 2 weeks
IPQ - Igroup Presence Questionnaire
A test that measures overall presence in VR. Dimensions: Spatial presence, engagement, realism. Scoring logic: Higher scores indicate greater presence. Reference: T. Schubert, F. Friedmann, and H. Regenbrecht, "The Experience of Presence: Factor Analytic Insights," Presence Teleoperators Virtual Environ., vol. 10, no. 3, pp. 266-281, June 2001, doi: 10.1162/105474601300343603.
Time frame: From enrollment to the end of treatment at 2 weeks
VRSQ - Virtual Reality Sickness Questionnaire
It measures Cybersickness / motion sickness symptoms. Dimensions: General malaise, vestibular symptoms. Scoring logic: Higher scores indicate greater malaise. Reference: H. K. Kim, J. Park, Y. Choi, and M. Choe, "Virtual reality sickness questionnaire (VRSQ): Motion sickness measurement index in a virtual reality environment," Appl. Ergon., vol. 69, pp. 66-73, May 2018, doi: 10.1016/j.apergo.2017.12.016.
Time frame: From enrollment to the end of treatment at 2 weeks
VAS Scale
It measures: * Odor intensity (experimental only) * Odor liking (experimental only) * Odor familiarity (experimental only) * Perceived time pressure (both groups) Meaning: Higher scores indicate greater perceived intensity/liking/familiarity/pressure (depending on the item). Reference: M. Koo y S.-W. Yang, "Visual Analogue Scale", Encyclopedia, vol. 5, n.o 4, nov. 2025, doi: 10.3390/encyclopedia5040190.
Time frame: From enrollment to the end of treatment at 2 weeks
UEQ-S - User Experience Questionnaire Short
It masures the user experience. Dimensions: Pragmatic and hedonic. Scoring logic: Higher scores indicate better user experience. Reference: M. Schrepp, A. Hinderks, and J. Thomaschewski, "Design and Evaluation of a Short Version of the User Experience Questionnaire (UEQ-S)," Int. J. Interact. Multimed. Artif. Intell., vol. 4, no. 6, pp. 103-108, Dec. 2017.
Time frame: From enrollment to the end of treatment at 2 weeks
Performance rate
Measures of the number of correct answers, response time, and use of clues
Time frame: From enrollment to the end of treatment at 2 weeks
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Plan to share: No
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