An interventional study of Conventional Exercise programs and Dynamic Neuromuscular Stabilization in Hemiplegia, Vestibular Exercises and Physiotherapy and Rehabilitation, sponsored by Istanbul Medipol University Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-08-06.
Sponsored by Istanbul Medipol University Hospital · Not applicable, Interventional, and Treatment
This study will aim to investigate the effects of vestibular rehabilitation, dynamic neuromuscular stabilization (DNS), and conservative rehabilitation exercises on balance and mobility in hemiplegic patients, and to compare the exercise programs with one another. Evaluation tools include the Brunnstrom Motor Staging, Fugl-Meyer Upper Extremity Motor Function Scale, Modified Ashworth Scale, Mini-Mental State Examination, Berg Balance Scale, Stroke Impact Scale, and Timed Up and Go test.
This study will aim to investigate the effects of vestibular rehabilitation, dynamic neuromuscular stabilization (DNS), and conservative rehabilitation exercises on balance and mobility in hemiplegic patients, and to compare the exercise programs with one another. A total of 45 hemiplegic patients will enrolled and randomized into three groups: Conventional Exercise Group (CEG, n = 15), Dynamic Neuromuscular Stabilization Group (DNSG, n = 15), and Vestibular Rehabilitation Group (VRG, n = 15). Each group will be participated in specialized exercise programs twice a week for six weeks. All groups will be underwent assessments before and after treatment. Evaluation tools include the Brunnstrom Motor Staging, Fugl-Meyer Upper Extremity Motor Function Scale, Modified Ashworth Scale, Mini-Mental State Examination, Berg Balance Scale, Stroke Impact Scale, and Timed Up and Go test.
374 studies on the registry are indexed under Hemiplegia; 83 are open to participants now.
This study's enrollment of 45 is above the median of 34 across 310 interventional studies indexed under Hemiplegia.
Browse Hemiplegia studies →Istanbul Medipol University Hospital is the lead sponsor of 350 studies on the registry; 58 are open to participants now.
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Exclusion Criteria:
Conventional Exercise will be conducted in this group
Other: Conventional Exercise programs
Dynamic Neuromuscular Stabilization exercises will be done in this group
Other: Dynamic Neuromuscular Stabilization
Vestibular Rehabilitation will be conducted in this group
Other: Vestibular Rehabilitation Group
This group participated in Conventional Exercise programs twice a week for six weeks.
This group participated in Dynamic Neuromuscular Stabilization Exercise programs twice a week for six weeks.
This group participated in Vestibular Rehabilitation programs twice a week for six weeks.
The Fugl-Meyer Assessment of Upper Extremity
It is a standardized, stroke-specific, performance-based outcome measure used in clinical trials to evaluate motor recovery of the upper limb. It assesses movement, coordination, and reflex activity of the shoulder, elbow, forearm, wrist, and hand, providing a quantitative measure of motor impairment and recovery over time. The maximum score for the arm section is 36. During the finger-to-nose test, coordination and speed of movement are evaluated out of 6 points, while tremor, dysmetria, and speed of movement in the upper extremity are also examined in detail.
Time frame: From the beginning of treatment to the end of the 6th week
Modified Ashworth Scale (MAS)
It is a widely used clinical outcome measure in clinical trials to assess spasticity by grading the resistance encountered during passive muscle stretching. The joint is passively moved with repetitive and rapid movements, and the joint's resistance to these movements is scored.
Time frame: From the beginning of treatment to the end of the 6th week
Mini-Mental State Examination (MMSE)
It is a brief, standardized cognitive screening tool used in clinical trials to assess global cognitive function, including orientation, attention, memory, language, and visuospatial abilities. The total score ranges from 0 to 30, with higher scores indicating better cognitive performance. Scores of 24-30 indicate normal cognition, 18-23 mild cognitive impairment, and ≤17 moderate to severe cognitive impairment.
Time frame: From the beginning of treatment to the end of the 6th week
Berg Balance Scale (BBS)
This is a 14-item scale that assesses a patient's ability to maintain balance for a specific period during static and various functional movements. The scoring system ranges from 0 to 4, with 0 meaning "cannot" and 4 meaning "can do independently," and the maximum total score is 56. A total score between 0-20 indicates a high risk of falls; between 21-40 indicates a moderate risk of falls; and between 41-56 indicates a low risk of falls.
Time frame: From the beginning of treatment to the end of the 6th week
Stroke Impact Scale (SIS)
It is a stroke-specific, patient-reported outcome measure widely used in clinical trials to evaluate the perceived impact of stroke on multiple domains of health-related quality of life. Based on the obtained score, 0 indicates no recovery, whereas 100 represents complete recovery.
Time frame: From the beginning of treatment to the end of the 6th week
Timed Up and Go (TUG)
The test is a simple and widely used functional mobility assessment in clinical trials. It measures the time required for an individual to stand up from a chair, walk 3 meters, turn around, walk back, and sit down. Shorter completion times indicate better functional mobility and balance, and the test is commonly used to assess fall risk and mobility limitations.
Time frame: From the beginning of treatment to the end of the 6th week
Plan to share: No — Individual participant data (IPD) will be made available to other researchers upon reasonable request, if deemed necessary.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Istanbul Medipol University Hospital