ClinicalTrials.gg
CompletedNCT07384299Updated Feb 3, 2026

Impact of Skin Type on Wonud Healing and Scarring Following Facial Skin Surgery

An observational study in Nevus, Seborrheic Keratosis (SK) and Cyst, sponsored by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. Completed at 1 site in China. Open to participants aged 14 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-02-03.

Sponsored by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
173
Ages
14 Years to 60 Years
Sex
All
01

Study summary

The goal of this observational study is to learn how an individual's skin type influences the wound healing process and scar formation in Chinese patients undergoing facial dermatologic surgery. The main questions it aims to answer are:

How does skin type affect the quality of wound healing after facial surgery?

How does skin type affect the formation of hypertrophic scars after facial surgery?

Researchers will compare groups of patients with different skin types (classified by the Baumann Skin Type) to see if there are significant differences in their healing outcomes and scar characteristics.

Participants in this study will:

Receive standard facial dermatologic surgery as part of their clinical care.

Have their skin type assessed preoperatively.

Undergo scheduled postoperative follow-up assessments at 7 and 90 days to evaluate wound healing and scar development using standardized scales.

02

Conditions studied

  • Nevus
  • Seborrheic Keratosis (SK)
  • Cyst
  • Lipoma
  • Scar
03

In context

Nevus

47 studies on the registry are indexed under Nevus; 9 are open to participants now.

This study's enrollment of 173 is above the median of 145 across 28 observational studies indexed under Nevus.

Browse Nevus studies →

Lead sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology is the lead sponsor of 181 studies on the registry; 144 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
14 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

patients undergoing facial skin surgery to remove benign lesions

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Aged between 14 and 60 years.
  • Clinically and postoperatively diagnosed with a facial benign tumor (e.g., melanocytic nevus, sebaceous cyst, seborrheic keratosis, etc.) and having undergone standard surgical treatment.
  • Voluntary participation in this study with written obtained.
  • Commitment to comply with all study protocols and to complete all follow-up visits and data collection procedures.

Exclusion criteria

Exclusion Criteria:

  • Clinically or postoperatively diagnosed with a facial malignant tumor.
  • Wounds requiring staged excision or planned for secondary intention healing.
  • Surgical site located on or adjacent to the mucosal surface.
  • Known history of allergy to any medications or dressings to be used during or after surgery.
  • Presence of systemic diseases that significantly impair wound healing (e.g., poorly controlled diabetes, immunodeficiency disorders, active infections).
  • Current use of medications affecting wound healing or scar formation (e.g., long-term systemic , ).
  • Pregnancy or lactation.
  • Refusal to provide written , or anticipated inability to comply with study follow-up and data collection.
  • Concurrent participation in another interventional clinical trial.
  • Any other condition deemed by the investigator as likely to interfere with study results or increase participant risk.
Terms in these criteria, in plain language(4)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Histologically or cytologically confirmed

The diagnosis was confirmed by looking at a sample under a microscope: tissue from a biopsy or surgery (histology), or cells from a fluid or needle sample (cytology).

Your pathology report is the document that shows this.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

Immunosuppression

A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.

Read whether the line is about a condition or about medicines, and which medicines and doses it means.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
173 participants (actual)
Patient registry
No

Groups and cohorts

  • Oily Skin

    classified as having oily skin according to the Baumann questionnaire

  • Dry Skin

    classified as having dry skin according to the Baumann questionnaire

06

What researchers measure

Primary outcomes

  1. Patient and Observer Scar Assessment Scale version 2.0 (POSAS 2.0)

    This scale comprises two separate subscales: the Observer Scar Assessment Scale (completed by the clinician) and the Patient Scar Assessment Scale (completed by the participant). The Observer Scale evaluates six items (vascularity, pigmentation, thickness, relief, pliability, and surface area) on a scale from 1 ("like normal skin") to 10 ("the worst scar imaginable"), with a total score ranging from 6 (best) to 60 (worst). The Patient Scale evaluates six items (pain, itching, color, stiffness, thickness, and irregularity) on a scale from 1 ("no, not at all") to 10 ("yes, very much"), with a total score also ranging from 6 (best) to 60 (worst). For both subscales, a higher score indicates a worse scar quality.

    Time frame: 3-month follow-up

  2. modified Stony Brook Scar Evaluation Scale (mSBSES)

    Evaluations were independently performed by two clinicians who were blinded to group allocation. The scale comprises four items: scar width, height, color, and suture marks. Each item is scored from 0 to 2 points, where a score of 2 represents the closest resemblance to normal skin, and 0 represents the worst appearance. The total score ranges from 0 to 8, with a higher score indicating a more ideal scar appearance.

    Time frame: 3-month follow-up

Secondary outcomes

  1. Incidence of Postoperative Edema

    Assessed by direct clinical examination. Unit: % of participants with the presence of edema.

    Time frame: 7-day follow-up

  2. Incidence of Wound Suppuration

    7-day follow-up

    Time frame: Assessed by direct clinical examination. Unit: % of participants with the presence of suppuration.

  3. Incidence of Peri-wound Erythema

    Assessed by direct clinical examination. Unit: % of participants with the presence of erythema.

    Time frame: 7-day follow-up

  4. Incidence of Wound Tenderness

    Assessed by patient report. Unit: % of participants reporting tenderness.

    Time frame: 7-day follow-up

  5. Incidence of Postoperative Hemorrhage

    Assessed by direct clinical examination. Unit: % of participants with active bleeding or hematoma formation.

    Time frame: 7-day follow-up

  6. Incidence of Peri-wound Ecchymosis

    Assessed by direct clinical examination. Unit: % of participants with the presence of ecchymosis.

    Time frame: 7-day follow-uo

07

Study locations

1 site
  • Not Appicable
    Wuhan, Hubei 430022, China
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jun 2025 to primary completion in Jan 2026, 7 months.

Of 14 observational studies under Nevus, half reached primary completion within 34 months of starting (the median), counting those still running; a quarter within 21 and three quarters within 104. This study's 7 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 18, 2026
First posted
Feb 3, 2026
StartActual
Jun 15, 2025
Primary completionActual
Jan 15, 2026
CompletionActual
Jan 15, 2026
Last update
Feb 3, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 3, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07384299
Responsible party
YangLiu82 (Deputy Head of the Dermatology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology) — Principal investigator
First posted
Feb 3, 2026
Start date
Jun 15, 2025
Primary completion
Jan 15, 2026
Completion
Jan 15, 2026
Last update
Feb 3, 2026
View the source record on ClinicalTrials.gov ↗

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