ClinicalTrials.gg
RecruitingNCT07366970Updated Jan 26, 2026

Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D?

An interventional study of exercise and vitamin D intake and vitamin D intake in Diabetes Mellitus, Erectile Dysfunction and Vitamin D Deficiency, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to male participants aged 35 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-01-26.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by May 2026, 6 months ago, but the record still lists the study as recruiting.
  • Started Dec 2025; still recruiting 11 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
35 Years to 45 Years
Sex
Male
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 36 studies in Diabetes Mellitus by Cairo University — 7 open to participants now, 9 under way, none of them phase 3. Diabetes Mellitus · Cairo University.

Planned enrollment
21st of 26
40 · median 53
Started
2025
with 1 other
No phase
24 of 36
6 open now
Registered
32nd of 36
by date

Among the 36 studies in Diabetes Mellitus by Cairo University, this one is the 21st largest by planned enrollment of the 26 interventional ones that give a count, is one of 2 that started in 2025, is one of 24 with no phase, and was the 32nd registered.

Diabetes Mellitus

8,291 studies on the registry are indexed under Diabetes Mellitus; 1,075 are open to participants now.

Browse Diabetes Mellitus studies →

Open to participants now

7 of the 36 studies in Diabetes Mellitus by Cairo University are open now, in 1 country. Recruiting first, the newest first:

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By country, each count listing its studies:

All 7 open studies →

Where they have run

Who these studies take

Of the 649 Diabetes Mellitus studies recruiting now, 357 (55%) set no upper age limit and 197 (30%) stop at 75 or younger; 88 take children under 18; 183 take healthy volunteers.

This study: 35 Years to 45 Years · male · no healthy volunteers.

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02

Study summary

males with diabetes complain impotence in the presence of low vitamin D deficiency. pharacmological treatment of low vitamin D levels is necessary but changing lifestyle by performing exercise is also important

Read the detailed description

forty diabetic men (type 2) who complain presence of low vitamin D and impotence will be divided to group number I and group number II. Both groups will be pharmacologically treated by administration of Cholecalciferol 200.000 I.U (will be taken every two weeks). this treatment will last for 12 weeks. Additionally, Group number I will perform treadmill walking (one hour walking) with moderate intensity. This walking will be performed three times per designed week for twelve weeks.

03

Conditions studied

  • Diabetes Mellitus
  • Erectile Dysfunction
  • Vitamin D Deficiency
04

Who can participate

Ages eligible
35 Years to 45 Years
Sexes eligible
Male
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • diabetic men (forty)
  • type 2 diabetes
  • complaint of erectile dysfucntion (chronic complaint more than 24 months)
  • men with low vitamin D (deiciency in vitamin D)

Exclusion criteria

Exclusion Criteria:

  • cardiac patients
  • respiratory disease patients
  • renal disease
  • liver disease
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    group number 1

    twenty diabetic men (type 2) who complain presence of low vitamin D and impotence will be pharmacologically treated by administration of Cholecalciferol 200.000 I.U (will be taken every two weeks). this treatment will last for 12 weeks. Additionally, Group number I will perform treadmill walking (one hour walking) with moderate intensity. This walking will be performed three times per designed week for twelve weeks.

    Behavioral: exercise and vitamin D intake

  • Active comparator
    group number 2

    twenty diabetic men (type 2) who complain presence of low vitamin D and impotence will be pharmacologically treated by administration of Cholecalciferol 200.000 I.U (will be taken every two weeks). this treatment will last for 12 weeks.

    Other: vitamin D intake

Interventions

  • Behavioralexercise and vitamin D intake

    twenty diabetic men (type 2) who complain presence of low vitamin D and impotence will be pharmacologically treated by administration of Cholecalciferol 200.000 I.U (will be taken every two weeks). this treatment will last for 12 weeks. Additionally, Group number I will perform treadmill walking (one hour walking) with moderate intensity. This walking will be performed three times per designed week for twelve weeks.

  • Othervitamin D intake

    twenty diabetic men (type 2) who complain presence of low vitamin D and impotence will be pharmacologically treated by administration of Cholecalciferol 200.000 I.U (will be taken every two weeks). this treatment will last for 12 weeks.

06

What researchers measure

Primary outcomes

  1. international index of erectile function

    questionnaire used to assess impotence

    Time frame: it will be measured after 12 weeks

Secondary outcomes

  1. glycated hemoglubin

    it will be used to assess blood glcuose

    Time frame: It will be measured after 12 weeks

  2. fasting blood glcuose

    it will be used to assess blood glcuose in serum

    Time frame: It will be measured after 12 weeks

  3. body mass index

    it will be measured on empty stomach and bladder

    Time frame: It will be measured after 12 weeks

  4. wasit circumference

    it will be measured at umbilicus level

    Time frame: it will be measured after 12 weeks

  5. high density lipoprotein

    it will be measured in serum

    Time frame: It will be measured after 12 weeks

  6. low density lipoprotein

    it will be measured in serum

    Time frame: It will be measured after 12 weeks

  7. triglycerides

    it will be assessed in serum

    Time frame: It will be measured after 12 weeks

  8. cholesterol

    it will be assessed in serum

    Time frame: It will be measured after 12 weeks

  9. 25-hydroxyvitamin D

    it will be assessed in serum as a metabolite of vitamin D

    Time frame: It will be measured after 12 weeks

07

Study locations

1 of 1 sites recruiting
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Dec 2025 (actual). Primary completion is estimated for May 2026, 5 months after the start.

Of 1,584 non-industry interventional studies with no phase under Diabetes Mellitus, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 43. This study's planned 5 months is below that.

Counting every sponsor, half of 1,744 studies reached it within 21 months; a quarter within 9 and three quarters within 42.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 17, 2026
First posted
Jan 26, 2026
StartActual
Dec 5, 2025
Primary completionEst.
May 5, 2026
CompletionEst.
May 5, 2026
Last update
Jan 26, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jan 26, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07366970
Lead sponsor
Cairo University
Responsible party
Ali Mohamed Ali ismail (lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Cairo University) — Principal investigator
First posted
Jan 26, 2026
Start date
Dec 5, 2025
Primary completion
May 5, 2026 (estimated)
Completion
May 5, 2026 (estimated)
Last update
Jan 26, 2026

Study contacts

Ali MA Ismail, lecturer
Contact
ali.mohamed@pt.cu.edu.eg
01005154209
Ali mohamed, lecturer
Contact
fatmaraed1994@gmail.com
01031321109
Ali MA Ismail, lecturer
principal investigator · Cairo University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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