CClinicalTrials.gg
Not yet recruitingNCT07361575POGUpdated Feb 17, 2026

Study Comparing the Quality of Colon Cleanliness With Prepackaged LRD (Low-residue Diet) vs. Guided (POG).

An interventional study of Colonoscopy and Questionnaires in Colorectal Cancer Prevention, Colorectal Cancer (Diagnosis) and Colorectal Adenocarcinoma, sponsored by Clinique Paris-Bercy. Not yet recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-17.

Sponsored by Clinique Paris-Bercy · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
230
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Low-residue diet (LRD) in patient improves the quality of the colon cleanliness and thus the adenoma detection rate (ADR). This is a key criterion in colonoscopy screening for colorectal cancer (CRC). The benefit of an LRD lasting more than 24 hours before colonoscopy has not been demonstrated compared to a 24-hour LRD.

Few studies have evaluated the benefit of a prepackaged 24-hour LRD compared to simply receiving oral and written LRD instructions during a consultation.

The aim of the study is to evaluate the usefulness of a prepackaged LRD (Colobox®) compared to simple LRD instructions on colon cleanliness (Boston score) in patients examined by endoscopy.

02

Conditions studied

  • Colorectal Cancer Prevention
  • Colorectal Cancer (Diagnosis)
  • Colorectal Adenocarcinoma
03

In context

Colorectal Neoplasms

5,599 studies on the registry are indexed under Colorectal Neoplasms; 1,458 are open to participants now.

This study's planned enrollment of 230 is above the median of 77 across 4,122 interventional studies indexed under Colorectal Neoplasms.

Browse Colorectal Neoplasms studies →

Lead sponsor

Clinique Paris-Bercy is the lead sponsor of 6 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patient of one of the investigators for total colonoscopy (no prior colonic surgery);
  • Patient aged 18 years or older;
  • Patient classified as ASA 1, ASA 2, or ASA 3;
  • Not participating in any other current clinical trial;
  • Free, informed, and signed consent;
  • Patient affiliated with or a beneficiary of a social security scheme, according to Article L.1124-1 of the French Public Health Code;

Exclusion criteria

Exclusion Criteria:

  • Patient taking major psychotropic medications;
  • Patient with uncontrolled diabetes;
  • Patient with coagulation abnormalities preventing polypectomy: PT \<50%, Platelets \<50,000/mm³, current effective anticoagulation therapy (clopidogrel, prasugrel, or ticagrelor);
  • Patient referred for removal of a known polyp;
  • Chronic inflammatory bowel disease;
  • Known colonic stenosis;
  • Diverticulitis of less than 6 weeks duration;
  • Pregnant, parturient, or breastfeeding woman;
  • Patient deprived of liberty by administrative or judicial order, or under guardianship or limited legal protection;
  • Patient unable to understand the objectives and constraints of the study.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Care provider)
Enrollment
230 participants (estimated)

Study arms

  • Experimental
    Patient with LRD prepared 24 hours before colonoscopy

    The LRD prepared is Colobox

    Procedure: Colonoscopy · Other: Questionnaires · Other: Pre-colonoscopy diet by following a special preparation, Colobox.

  • Active comparator
    Patients with not prepared LRD, 24 hours before colonoscopy

    The LRD is only explained orally and in writing to the patient

    Procedure: Colonoscopy · Other: Questionnaires · Other: Pre-colonoscopy diet according to the investigator's oral instructions

Interventions

  • ProcedureColonoscopy

    Colonoscopy performed and Boston score evaluated

  • OtherQuestionnaires

    LRD satisfaction questionnaire LRD compliance questionnaire

  • OtherPre-colonoscopy diet according to the investigator's oral instructions

    24 hours before the colonoscopy, The patients follow a special diet, either by themselves according to the investigator's oral instructions

  • OtherPre-colonoscopy diet by following a special preparation, Colobox.

    24 hours before the colonoscopy, The patients follow a special diet, by following a special preparation, Colobox.

06

What researchers measure

Primary outcomes

  1. Boston Score

    A 9-point system, helps them see how clean a patient's large intestine is during a colonoscopy. This scale divides the large intestine into three parts: right, middle, and left. Each part can score from : BBPS = 0 (per segment) : unprepared colon segment with mucosa not seen because of solid stool that cannot be cleared. BPPS=3 (per segment) : entire mucosa of the colon segment seen well, with no residual staining, small fragments of stool, or opaque liquid.

    Time frame: 1 day

07

Study locations

1 site
  • Clinique Paris Bercy
    Charenton-le-Pont, 94220, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07361575
Lead sponsor
Clinique Paris-Bercy
Responsible party
Sponsor
First posted
Jan 23, 2026
Start date
Jan 30, 2026 (estimated)
Primary completion
Nov 15, 2026 (estimated)
Completion
Nov 30, 2026 (estimated)
Last update
Feb 17, 2026

Study contacts

Coralie DE CLERCK
Contact
c.declerck@clinique-bercy.fr
0033143967823

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.

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