ClinicalTrials.gg
RecruitingNCT07361172Updated Jan 22, 2026

Ready-made vs. Custom-made Carriere Motion Appliance

An interventional study of Custom-made Carriere motion appliance and Ready-made Carriere motion appliance in Class II Malocclusion, sponsored by Mansoura University. Recruiting at 1 site in Egypt. Open to participants aged 12 Years to 16 Years. Per ClinicalTrials.gov, last updated 2026-01-22.

Sponsored by Mansoura University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 6 months after the study started (first participant enrolled Jan 2025, registered Aug 2025).
  • Started Jan 2025; still recruiting 1 year 9 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
24
Allocation
Randomized
Ages
12 Years to 16 Years
Sex
All
01

Study summary

The aim of this study is to evaluate the effect of custom-made CMA vs. the ready-made CMA.

Read the detailed description

The aim of this study is to evaluate the effect of custom-made CMA from brackets, buccal tubes, stiff wire, and NiTi coil springs and compare it with the ready-made CMA.

02

Conditions studied

  • Class II Malocclusion

Keywords

  • Class II malocclusion
  • Carriere motion appliance
  • Distalization
03

In context

Lead sponsor

Mansoura University is the lead sponsor of 1,119 studies on the registry; 183 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
12 Years to 16 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients age (12-15) years.
  • Full permanent dentition.
  • Class II malocclusion with at least an end-on Class II molar relationship bilaterally.

Exclusion criteria

Exclusion Criteria:

  • Systemic conditions that may interfere with the treatment.
  • Bad habits that might jeopardize the appliance.
  • Transverse discrepancy.
  • Previous orthodontic treatment.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
24 participants (estimated)

Study arms

  • Experimental
    Custom-made CMA

    Custom-made CMA from brackets, buccal tubes, stiff wire, and NiTi coil springs

    Device: Custom-made Carriere motion appliance

  • Active comparator
    Ready-made CMA

    Device: Ready-made Carriere motion appliance

Interventions

  • DeviceCustom-made Carriere motion appliance

    custom-made CMA from brackets, buccal tubes, stiff wire, and NiTi coil springs to treat class II malocclusion by molar distalization.

  • DeviceReady-made Carriere motion appliance

    Ready-made Carriere motion appliance to treat class II malocclusion by molar distalization.

06

What researchers measure

Primary outcomes

  1. Treatment duration

    in about 6 months from the start of treatment till reaching class I molar relation

    Time frame: up to 6 months from the start of treatment until the date of first documented progression

  2. Skeletal and dental changes

    angular and linear cephalometric measurements

    Time frame: up to 6 months from the start of treatment until the date of first documented progression

Secondary outcomes

  1. Soft tissue changes

    angular and linear cephalometric measurements

    Time frame: up to 6 months from the start of treatment until the date of first documented progression

  2. Patient satisfaction

    patient questionnaire about oral health related quality of life: their satisfaction and discomfort

    Time frame: up to 6 months from the start of treatment until the date of first documented progression

07

Study locations

1 of 1 sites recruiting
  • Faculty of Dentistry, Mansoura University
    Al Mansurah, Adakhlia 35511, Egypt
    Recruiting
    • Eglal A. Ghozy, PhD · Contacteglalghozy@gmail.com · 01121441414
    • Eglal A. Ghozy, PhD · Principal investigator
    • Nehal F. Albelasy, PhD · Sub investigator
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07361172
Responsible party
Sponsor
First posted
Jan 22, 2026
Start date
Jan 13, 2025
Primary completion
Aug 13, 2025
Completion
Jan 13, 2026 (estimated)
Last update
Jan 22, 2026

Study contacts

Eglal A. Ghozy, PhD
Contact
eglalahmed@mans.edu.eg
+201121441414

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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