An interventional study of MRI examination and Smell and taste capacity testings in Anorexia Nervosa, sponsored by Centre Hospitalier Universitaire de Saint Etienne. Not yet recruiting at 1 site in France. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-16.
Sponsored by Centre Hospitalier Universitaire de Saint Etienne · Not applicable, Interventional, and Basic science
Among 79 studies in Anorexia Nervosa with a site in France — 16 open to participants now, 21 under way, 1 of them phase 3. Anorexia Nervosa · France.
Among the 79 studies in Anorexia Nervosa with a site in France, this one is the 15th largest by planned enrollment of the 48 interventional ones, is one of 3 that started in 2026, is one of 45 with no phase, reaches primary completion later than 12 of the 20 other live ones, and was the 77th registered.
469 studies on the registry are indexed under Anorexia Nervosa; 127 are open to participants now.
This study's planned enrollment of 90 is above the median of 46 across 313 interventional studies indexed under Anorexia Nervosa.
Browse Anorexia Nervosa studies →16 of the 79 studies in Anorexia Nervosa with a site in France are open now, in 1 country. Each count lists the studies.
Of the 83 Anorexia Nervosa studies recruiting now, 18 (22%) set no upper age limit and 61 (73%) stop at 75 or younger; 48 take children under 18; 26 take healthy volunteers.
This study: 18 Years and older · female · healthy volunteers too.
The full table on the hub →79 studies; the count open now beside each. This study's row is marked.
First in 2009; this study’s year is marked. 3 started in 2026.
Median enrollment 56 across the 48 interventional studies, 87 across the 31 observational. Of the 47 that completed or were terminated, 0 (0%) have results posted.
None of the 79 has an industry lead sponsor. The 10 most frequent:
Centre Hospitalier Universitaire de Saint Etienne is the lead sponsor of 597 studies on the registry; 127 are open to participants now.
Centre Hospitalier Universitaire de Saint Etienne has 9 studies filed under Anorexia Nervosa — fewer than ten, so there is no comparison to draw.
9 of the studies in Anorexia Nervosa with a site in France that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06091306Assistance Publique - Hôpitaux de ParisQualitative Evaluation of Change Processes in Multifamily Therapy for Adolescents With Anorexia Nervosa | 2026-12 |
| NCT05770089University Hospital, CaenVideoconferencing Adapted Physical Activity in Anorexia Nervosa: a Pilot Study | 2026-12-01 |
| NCT04107870CHU de ReimsEfficiency of Virtual Reality Exposure Therapy in the Management of Body Dysmorphic Disorders in Female Adolescents With Anorexia Nervosa | 2027-03-20 |
| NCT07411807Centre Hospitalier St AnneStudy of the Effectiveness of a Systematic Minimal Early Intervention on Care Engagement in Adults With Eating Disorders Requesting Specialized Treatment. | 2027-04 |
| NCT05477537Fondation Santé des Étudiants de FranceAdapted Physical Activity in the Treatment of Anorexia: | 2027-04 |
Among the 79 studies in Anorexia Nervosa with a site in France, from their registry updates:
Lipid restriction is significant in anorexia nervosa and limits therapeutic management. The multisensory perception of fat is altered, creating an aversion to lipids. The investigators aim to characterize the impact of sensory stimulation (smells or images) associated with specific tastes using neuropsychological assessments and functional MRI. Some volatile aromas can enhance the perception of the associated taste. The investigators hypothesize that such associations are altered in anorexia nervosa for fatty foods but may be preserved for sweet tastes, and that this alteration contributes to the maintenance of the disease. The interdependence of different sensory perceptions of lipids could play a major role in the therapeutic approach, aiding in the deconditioning of this aversion and the restoration of positive food sensory associations.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
30 patients with anorexia nervosa
Other: MRI examination · Other: Smell and taste capacity testings
30 control subjects of normal weight
Other: MRI examination · Other: Smell and taste capacity testings
30 control subjects with a similar weight to AN patients (the constitutional thinness group)
Other: MRI examination · Other: Smell and taste capacity testings
One hour MRI examination
one hour sensory testings
Brain activity measured by functional MRI
Estimation of the "fatty vs. neutral" contrast when all three senses are used, comparing AN patients to the normal-weight control group (NC group) in each voxel of the brain volume (whole-brain analysis) and in the orbitofrontal cortex (ROI analysis).
Time frame: Day 1
Brain activity measured by functional MRI
Estimation of the "fatty vs. neutral" contrast when all three senses are used, comparing AN patients to the control group with a similar BMI (CT group) in each voxel of the brain volume (whole-brain analysis) and in the orbitofrontal cortex (ROI analysis).
Time frame: Day 1
Brain activity measured by functional MRI
BOLD signal variations between the groups (AN, NC, and CT) for the "sweet vs. neutral" contrast.
Time frame: Day 1
Brain activity measured by functional MRI
BOLD signal variations for single vs. three senses simultaneously for each group and between groups for the "fatty vs. neutral" and "sweet vs. neutral" contrasts.
Time frame: Day 1
BMI
Body Mass Index
Time frame: DAY 1.
Olfactory and gustatory abilities
MediSens tests of olfactory and gustatory abilities
Time frame: Day 1
3DT1 morphological MRI
Brain morphometric measures and voxel-based morphometry.
Time frame: Day 1
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Dec 2026; primary completion for Nov 2027, 11 months later.
Of 151 non-industry interventional studies with no phase under Anorexia Nervosa, half reached primary completion within 43 months of starting (the median), counting those still running; a quarter within 24 and three quarters within 63. This study's planned 11 months is below that.
Counting every sponsor, half of 151 studies reached it within 43 months; a quarter within 24 and three quarters within 63.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Centre Hospitalier Universitaire de Saint Etienne →