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Not yet recruitingNCT07307326Updated Jul 8, 2026

Biomarker Feedback Intervention

An interventional study of eCHECKUP TO GO (eCTG) and eCHECKUPTOGO + brief personalized alcohol biomarker feedback intervention (eCTG + TAC) in High Risk Drinking and College Student Drinking, sponsored by Penn State University. Not yet recruiting at 1 site in United States. Open to participants aged 18 Years to 23 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-08.

Sponsored by Penn State University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
150
Allocation
Randomized
Ages
18 Years to 23 Years
Sex
All
01

Study summary

The goal of the study is to examine alcohol use behaviors of young adults through the use of testing the feasibility of adding an innovative brief personalized alcohol biomarker feedback component (TAC feedback) to an existing efficacious personalized feedback intervention, eCHECKUP TO GO (eCTG), and how (if at all) the intervention impacts drinking behaviors in high-risk college students. The study will conduct a feasibility assessment of the TAC feedback component, and will also assess the effects of the eCTG + TAC at 6-months post-baseline relative to an eCTG only group.

02

Conditions studied

  • High Risk Drinking
  • College Student Drinking

Keywords

  • college student drinking
03

In context

Alcohol Drinking in College

38 studies on the registry are indexed under Alcohol Drinking in College; 8 are open to participants now.

This study's planned enrollment of 150 is below the median of 258 across 36 interventional studies indexed under Alcohol Drinking in College.

Browse Alcohol Drinking in College studies →

Lead sponsor

Penn State University is the lead sponsor of 270 studies on the registry; 53 are open to participants now.

Of its 15 completed or terminated interventional studies of FDA-regulated products, 11 (73%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 23 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Between the ages of 18-23 at enrollment
  • Endorse drinking 4+/5+ (women/men) on a typical Friday or Saturday in the past 3-months
  • Report at least 1 alcohol-induced blackout in the past 3-months
  • Willing to wear a TAC sensor for 14 days at Waves 1 and 2

Exclusion criteria

Exclusion Criteria:

  • Younger than 18 at baseline
  • Not fluent in English
  • No Internet access
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
150 participants (estimated)

Study arms

  • Experimental
    eCHECKUP TO GO (eCTG)

    A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol

    Behavioral: eCHECKUP TO GO (eCTG)

  • Experimental
    eCHECKUPTOGO + brief personalized biomarker feedback intervention (eCTG + TAC)

    Participants will receive the eCHECKUPTOGO in addition to the transdermal alcohol concentration (TAC) personalized feedback. The TAC is a brief individually delivered intervention based on the principles of Motivational Interviewing and focuses on increasing students' motivation to reduce harmful drinking by drinking in a safer, less risky manner. Participants will receive information on their drinking (both from the TAC sensor and daily diary data). Participants will be asked about drinking events during the past 2 weeks (how reflective they were of typical patterns and if a night stood out as particularly negative). Students will receive information and visual representations about TAC rise rates and peaks, and then be shown how their drinking during the past 2 weeks maps onto those visuals.

    Behavioral: eCHECKUPTOGO + brief personalized alcohol biomarker feedback intervention (eCTG + TAC)

Interventions

  • BehavioraleCHECKUP TO GO (eCTG)

    A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol

  • BehavioraleCHECKUPTOGO + brief personalized alcohol biomarker feedback intervention (eCTG + TAC)

    Participants will receive the eCHECKUPTOGO in addition to the transdermal alcohol concentration (TAC) personalized feedback. The TAC is a brief individually delivered intervention based on the principles of Motivational Interviewing and focuses on increasing students' motivation to reduce harmful drinking by drinking in a safer, less risky manner. Participants will receive information on their drinking (both from the TAC sensor and daily diary data). Participants will be asked about drinking events during the past 2 weeks (how reflective they were of typical patterns and if a night stood out as particularly negative). Students will receive information and visual representations about TAC rise rates and peaks, and then be shown how their drinking during the past 2 weeks maps onto those visuals.

06

What researchers measure

Primary outcomes

  1. Examine changes in Transdermal Alcohol Concentration (TAC) rise rate

    TAC rise rate will be collected via the BACtrack Skyn wrist sensor, which measures transdermal alcohol concentration (TAC) in micrograms of ethanol per liter of air every 20 seconds to obtain biomarkers - rise rate is a TAC increase.

    Time frame: Baseline, 6 months

  2. Examine changes in Transdermal Alcohol Concentration (TAC) peak intoxication level

    TAC peak will be collected via the BACtrack Skyn wrist sensor, which measures transdermal alcohol concentration (TAC) in micrograms of ethanol per liter of air every 20 seconds to obtain biomarkers - peak is the maximum TAC recorded per day.

    Time frame: Baseline, 6 months

  3. Examine high risk drinking days

    Heavy episodic drinking (HED) days are recorded when women indicate drinking 4+ drinks in 2 hour window/men indicate drinking 5+ drinks in 2 hour window. High-intensity drinking (HID) days are recorded when women indicate drinking 8+ drinks in 2 hour window/men indicate drinking 10+ drinks in 2 hour window.

    Time frame: Baseline, 6 months

Secondary outcomes

  1. Examine negative consequences of alcohol use

    Alcohol related consequences (e.g., said or done embarrassing things) from the past 3 months will be measured using the established Brief Young Adult Alcohol Consequences Questionnaire. Response options will be on a 5-point scale ranging from (0) No or not in the past 3 months to (4) 4 or more times. Consequences will also be measures during the daily surveys on a Yes/No response scale.

    Time frame: Baseline, 6 months

  2. Examine Alcohol Use Disorder (AUD) symptoms

    Alcohol use disorder symptoms will be measured using the Alcohol Use Disorder Module of the SCID-5 and will be via in-person interview at baseline (past 12-months) and 6-month (past 6-months).

    Time frame: Baseline, 6 months

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: Yes — As part of funding requirements, data collected will be submitted to the NIAAA Data Archive.

Access criteria: Individuals will request access to the data via a data access request through the data archive.

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Oct 2026; primary completion for Dec 2027, 14 months later.

Of 23 interventional studies with no phase under Alcohol Drinking in College, half reached primary completion within 9 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 20. This study's planned 14 months is above that.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 15, 2025
First posted
Dec 29, 2025
StartEst.
Oct 15, 2026
Primary completionEst.
Dec 15, 2027
CompletionEst.
Dec 15, 2027
Last update
Jul 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07307326
Responsible party
Kimberly Mallett (Research Professor, Penn State University) — Principal investigator
First posted
Dec 29, 2025
Start date
Oct 15, 2026 (estimated)
Primary completion
Dec 15, 2027 (estimated)
Completion
Dec 15, 2027 (estimated)
Last update
Jul 8, 2026

Study contacts

Kimberly Mallett, PhD
Contact
kmallett@psu.edu
814-441-6398
Rob Turrisi, PhD
Contact
rturrisi@psu.edu
814-865-7808
Kimberly Mallett, PhD
principal investigator · The Pennsylvania State University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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