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RecruitingNCT07303920Updated Sep 25, 2026

Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day

An interventional study of Daily disposable contact lenses for astigmatism in Astigmatism, sponsored by Ohio State University. Recruiting at 1 site in United States. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-25.

Sponsored by Ohio State University · Not applicable, Interventional, and Other

From the registry’s dates

  • Started Mar 2026; still recruiting 8 months later.
Updated Sep 25, 2026Primary completion movedStudy completion movedGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Not applicable
Ages
18 Years to 40 Years
Sex
All
01

Study summary

The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.

02

Conditions studied

  • Astigmatism

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03

In context

Astigmatism

417 studies on the registry are indexed under Astigmatism; 50 are open to participants now.

This study's planned enrollment of 40 is below the median of 55 across 325 interventional studies indexed under Astigmatism.

Browse Astigmatism studies →

Lead sponsor

Ohio State University is the lead sponsor of 663 studies on the registry; 148 are open to participants now.

Of its 67 completed or terminated interventional studies of FDA-regulated products, 49 (73%) have results posted.

Browse Ohio State University studies →

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Current soft toric contact lens wearer with long hours of wear
  • Willing to follow the contact lens wearing schedule required by the study
  • Vision 20/25 or better with current soft toric contact lenses
  • Self-report completion of a comprehensive eye examination in the past two years

Exclusion criteria

Exclusion Criteria:

  • Have a history of corneal ocular surgery
  • Have current ocular inflammation or infection as assessed by the study investigator who will complete the study
  • Are past rigid contact lens wearers
  • Have a history of being diagnosed with dry eye or ocular allergies
  • Have known systemic health conditions that are thought to alter tear film physiology
  • Have a history of viral eye disease
  • Have a history of ocular surgery
  • Have a history of severe ocular trauma
  • Have a history of corneal dystrophies or degenerations
  • Have active ocular infection or inflammation
  • Are currently using isotretinoin-derivatives or ocular medications
  • Are pregnant or breast feeding
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Other
    Contact Lens Wear

    All participants will be fit with the study contact lenses for astigmatism

    Device: Daily disposable contact lenses for astigmatism

Interventions

  • DeviceDaily disposable contact lenses for astigmatism

    All participants will be fit with the study lenses

    Also known as: Dailies Total1 for Astigmatism

06

What researchers measure

Primary outcomes

  1. Comfort

    Proportion of participants with positive Visual Analog Scale (VAS, \>50 on a 0-100 scale)

    Time frame: Measured over 16 hours of wear

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it movedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Mar 2026 (actual). Primary completion is estimated for Dec 2026, 9 months after the start.

Of 77 non-industry interventional studies with no phase under Astigmatism, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 48. This study's planned 9 months is below that.

Counting every sponsor, half of 183 studies reached it within 12 months; a quarter within 4 and three quarters within 26.

Since we started tracking on Sep 25, 2026, the dates moved once, on Sep 25, 2026: primary completion Jun 2026 → Dec 2026 and completion Jun 2026 → Dec 2026.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Dec 23, 2025
First posted
Dec 26, 2025
StartActual
Mar 4, 2026
Primary completionEst.
Dec 30, 2026was Jun 2026
CompletionEst.
Dec 30, 2026was Jun 2026
Last update
Sep 25, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Primary completion
Jun 30, 2026→Dec 30, 2026
Sep 25, 2026
Study completion
Jun 30, 2026→Dec 30, 2026
Sep 25, 2026
Show all 1 update
  1. Sep 25, 2026
    Primary completion Jun 30, 2026→Dec 30, 2026
    Study completion Jun 30, 2026→Dec 30, 2026
    + 1 other change: verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07303920
Lead sponsor
Ohio State University
Collaborators
Alcon Research
Responsible party
Jennifer Fogt (Assistant Professor, Ohio State University) — Principal investigator
First posted
Dec 26, 2025
Start date
Mar 4, 2026
Primary completion
Dec 30, 2026 (estimated)
Completion
Dec 30, 2026 (estimated)
Last update
Sep 25, 2026

Study contacts

Study Coordinators
Contact
OPT-EyeStudies@osu.edu
614-292-8858

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

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Discussion

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