An observational study in Spinal Cord Injuries (SCI) and Osteoarthritis (OA), sponsored by Gaziosmanpasa Research and Education Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-28.
Sponsored by Gaziosmanpasa Research and Education Hospital · Observational
Spinal cord injury patients often present with musculoskeletal comorbidities, including osteoarthritis. Early detection of cartilage damage is important for preventing osteoarthritis progression. This study aims to compare the talar cartilage thicknesses of spinal cord injury patients with healthy subjects. The secondary aim is to investigate a correlation between the talar cartilage thickness and disease-related parameters. The patient group is to be assessed for talar cartilage thickness (via ultrasound), functional status, spasticity, and ambulation levels.
1,948 studies on the registry are indexed under Spinal Cord Injuries; 505 are open to participants now.
This study's enrollment of 76 is above the median of 60 across 323 observational studies indexed under Spinal Cord Injuries.
Browse Spinal Cord Injuries studies →Gaziosmanpasa Research and Education Hospital is the lead sponsor of 122 studies on the registry; 29 are open to participants now.
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Thirty-eight SCI patients who apply to Physical Medicine and Rehabilitation outpatient and inpatient clinic between November 2025-January 2026 will be included in the study.
Thirty-eight age, gender, and BMI-matched healthy participants who are literate, give oral and written consent without any additional disease will be formed as the control group.
Exclusion Criteria:
Spinal cord injury patients
Age, sex, and BMI matched healthy controls
Talar cartilage thickness
The talar cartilage of both lower extremities are to be assessed with ultrasound
Time frame: Baseline
Functional Independence Measure (FIM) score
Functional Independence Measure scores will be held for the patient group in order to assess functional independence. This 18-item scale ranges between 18-126, higher scores indicating better outcomes.
Time frame: Baseline
Modified Ashworth Scale (MAS)
The spasticity level of patients are to be recorded for both ankle flexor and extensors via Modified Ashworth Scale. This scale ranges from 0 to 4; 0 indicating no spasticity, and 4 indicating severe increase in muscle tone with rigid joint.
Time frame: Baseline
Walking Index for Spinal Cord Injury II (WISCI II)
Ambulatory status of the patients will be recorded with this measuring scale, ranging between 0 (non ambulatory) to 20 (able to walk 10 meters with no devices/orthosis/assistance).
Time frame: Baseline
Plan to share: Yes — The datasets of the study (patient and volunteer demographics, clinical data, and statistical data) will be shared after completion of the study with third parties upon reasonable request.
Supporting information: Study protocol, Sap
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This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Gaziosmanpasa Research and Education Hospital