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RecruitingNCT07279571Updated Aug 6, 2026

GYN-AIDE: Gynecologic Oncology Navigation Through AI-Driven Education

An observational study in Gynecologic Disease, sponsored by University of Southern California. Recruiting at 1 site in United States. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-06.

Sponsored by University of Southern California · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
48
Ages
18 Years and older
Sex
Female
01

Study summary

This study seeks to understand how endometrial cancer patients get medical information about cancer care and their satisfaction with those health-seeking methods. It also assesses patient interest in using an artificial intelligence educational resource.

Read the detailed description

AIM 1: Evaluate use of an AI chatbot for HPV vaccine counseling:

PRIMARY OBJECTIVE:

I. To determine patient satisfaction with using an AI chatbot for HPV vaccine counseling.

SECONDARY OBJECTIVE:

I. To understand how patients currently obtain information about cancer care, vaccines, and artificial intelligence.

II. To describe patient experience with the AI-chatbot for vaccine counseling.

AIM 2: Increase rates of HPV vaccine uptake:

PRIMARY OBJECTIVE:

I. To evaluate if implementation of an AI chatbot for HPV vaccine counseling can affect the HPV vaccination rate of new patients served in the gynecologic oncology clinic.

OUTLINE: This is an observational study.

Patients complete a survey on study.

02

Conditions studied

  • Gynecologic Disease
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients of the LA General gynecologic oncology clinic who meet the eligibility criteria.

Eligibility criteria

AI-chatbot Evaluation (Aim 1):

Inclusion Criteria:

  • Patient of the LA General gynecologic oncology clinic
  • Age 18 years or older
  • Previously obtained the HPV vaccination (initial chatbot evaluation)
  • Eligible for HPV vaccination (pilot intervention; age \<46)
  • Willing and able to provide informed consent

Exclusion Criteria:

  • Patients who do not speak English or Spanish
  • Patients who do not provide informed consent

HPV vaccination rate (Aim 2):

Inclusion Criteria:

  • Patient of the LA General gynecologic oncology clinic
  • Age 18 years or older
  • Obtained the HPV vaccine

Exclusion Criteria:

  • None
04

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
48 participants (estimated)

Groups and cohorts

  • Observational

    Patients complete a survey on study.

    Other: Non-Interventional Study

Interventions

  • OtherNon-Interventional Study

    Non-interventional study

    Also known as: Non-Interventional Observational Study, Noninterventional (Observational) Study

05

What researchers measure

Primary outcomes

  1. Patient Satisfaction Scores

    Patients will complete a survey to assess their satisfaction with using an AI chatbot for HPV vaccine counseling.

    Time frame: Up to 1 year

  2. HPV Vaccination Rate

    HPV vaccination rate for patients who received the HPV vaccine counseling with the AI-chatbot

    Time frame: Up to 1 year

Secondary outcomes

  1. Demographics of patients

    Will be analyzed using a qualitative description of the demographics of patients involved in this specific study.

    Time frame: Up to 1 year

06

Study locations

1 of 1 sites recruiting
  • Los Angeles General Medical Center
    Los Angeles, California 90033, United States
    Recruiting
07

Registry details

Key details

Study ID
NCT07279571
Lead sponsor
University of Southern California
Collaborators
National Cancer Institute (NCI)
Responsible party
Sponsor
First posted
Dec 12, 2025
Start date
Jun 12, 2026
Primary completion
Jun 9, 2027 (estimated)
Completion
Jun 9, 2028 (estimated)
Last update
Aug 6, 2026

Study contacts

Xiaoyue M Guo
principal investigator · University of Southern California

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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