An interventional study of Sugar-free-flavored sweet tasting solution and Placebo (sterile-water) in Injection Pain, Local Anesthesia Infiltration and Pain, sponsored by University of Jordan. Completed at 1 site in Jordan. Open to participants aged 6 Years to 12 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-06.
Sponsored by University of Jordan · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children.
The main question it aims to answer is:
Does SFSS reduce pain during dental local anesthesia compared to a placebo (plain water)? Researchers will compare the use of SFSS and a placebo to see which results in lower pain scores.
Participants will:
Receive SFSS or placebo before local anesthesia during two dental visits Have their pain measured using self-reported and observational pain scales Have their heart rate monitored during the procedure
10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.
This study's enrollment of 54 is below the median of 66 across 8,493 interventional studies indexed under Pain.
Browse Pain studies →University of Jordan is the lead sponsor of 131 studies on the registry; 20 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Sugar-free-flavored sweet tasting solution
Other: Placebo (sterile-water)
A sugar-free-flavored sweet tasting solution that is anticipated to reduce the pain of local anaesthesia injections
Placebo (sterile water)
Self-reported pain using faces pain scale-revised (FPS-r)
Pain intensity measured using the Faces Pain Scale - Revised (FPS-R), ranging from 0 to 10, where higher scores indicate greater pain.
Time frame: Immediately after local anesthetic injection
Observer-reported pain using Revised Face, Legs, Activity, Cry, Consolability Scale
Pain behavior measured using the Face, Legs, Activity, Cry, Consolability - Revised (FLACC-R) Scale, scored from 0 to 10, where higher scores indicate greater pain-related distress.
Time frame: During administration of the local anesthetic injection
Physiological-Heart Rate
Changes in heart rate measured in beats per minute (bpm); increases in heart rate indicate higher physiological arousal associated with pain
Time frame: Baseline and During Injection
Plan to share: Yes
No publications or documents are linked to this record.
Ran from Jan 2026 to primary completion in Apr 2026, 3 months.
Of 3,731 non-industry interventional studies with no phase under Pain, half reached primary completion within 10 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 23. This study's 3 months is below that.
Counting every sponsor, half of 3,830 studies reached it within 10 months; a quarter within 4 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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