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Not yet recruitingNCT07270965Updated Dec 8, 2025

Moisturization and Skin Hydration Study

An interventional study of Moisturizing while in shower/bath and Moisturizing after towel drying in Atopic Dermatitis (AD) and Atopic Dermatitis (Eczema), sponsored by University of British Columbia. Not yet recruiting at 1 site in Canada. Open to participants aged 12 Years to 18 Years. Per ClinicalTrials.gov, last updated 2025-12-08.

Sponsored by University of British Columbia · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Non-randomized
Ages
12 Years to 18 Years
Sex
All
01

Study summary

Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. The goal of this clinical study is to evaluate the preference of moisturizing while showering/bathing compared to after towel drying in adolescents aged 12-18 with eczema. The main question it aims to answer are:

  • Which moisturization technique is preferred: while showering/bathing or after towel drying?
  • How do these techniques affect investigator-assessed eczema severity, patient-reported itch scores, and objective skin hydration measurements?

Researchers will compare applying moisturizer while in the shower/bath to after towel drying and to which technique is preferred among participants and if there are different effects on eczema and skin hydration.

Participants will:

  • Apply moisturizer while showering/bathing for one month and after towel drying for one month.
  • Complete questionnaires on moisturization technique, skin feel, and itchiness.
  • Undergo skin hydration measurements using a Corneometer® CM825 device.
02

Conditions studied

  • Atopic Dermatitis (AD)
  • Atopic Dermatitis (Eczema)

Keywords

  • Atopic Dermatitis
  • Eczema
  • AD
  • Moisturizer
  • Cream
  • Skin Hydration
03

In context

Dermatitis, Atopic

1,419 studies on the registry are indexed under Dermatitis, Atopic; 258 are open to participants now.

This study's planned enrollment of 30 is below the median of 83 across 1,125 interventional studies indexed under Dermatitis, Atopic.

Browse Dermatitis, Atopic studies →

Lead sponsor

University of British Columbia is the lead sponsor of 1,309 studies on the registry; 253 are open to participants now.

Of its 6 completed or terminated interventional studies of FDA-regulated products, 1 (17%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
12 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Participants must have a diagnosis of atopic dermatitis/eczema.
  • Participants must be between the age of 12-18.
  • Participants must be able to bathe independently.
  • Participants will be English speaking and able to complete questionnaires.

Exclusion criteria

Exclusion Criteria:

  • Participants who use topical corticosteroids between one inch above the wrist and 1 inch below the elbow from 1 month on both arms prior to the study until the final visit.
  • Participants who have a known allergy to the moisturizer cream (Cerave Moisturizing Cream) provided.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Non-randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Moisturizing while in shower/bath

    Behavioral: Moisturizing while in shower/bath

  • Experimental
    Moisturizing after towel drying

    Behavioral: Moisturizing after towel drying

Interventions

  • BehavioralMoisturizing while in shower/bath

    Applying moisturizer in the shower/bath.

  • BehavioralMoisturizing after towel drying

    Applying moisturizer out of the shower/bath after towel drying.

06

What researchers measure

Primary outcomes

  1. Proportion of Participants Preferring Each Moisturization Technique

    Participant reported preference of moisturization technique

    Time frame: Through study completion, an average of 2 months.

Secondary outcomes

  1. Skin Hydration Level

    Skin electrical capacitance measured using Corneometer® CM825 as an indicator of skin hydration.

    Time frame: Through study completion, an average of 2 months.

Other outcomes

  1. Eczema Severity Score

    Eczema severity will be assessed by clinicians using the Validated Investigator Global Assessment Scale for Atopic Dermatitis (vIGA-AD™). Scores range from 1 to 4, with higher scores indicating more severe eczema/atopic dermatitis (worse outcome).

    Time frame: Through study completion, an average of 2 months.

  2. Itch Intensity

    Itch intensity will be assessed using a patient-reported Numeric Rating Scale (NRS) ranging from 1 to 10, where higher scores indicate greater itch severity (worse outcome). Participants will report both average itch and worst itch experienced within the past 24 hours.

    Time frame: Through study completion, an average of 2 months.

07

Study locations

1 site
  • BC Children's Hospital
    Vancouver, British Columbia, Canada
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be shared, but aggregated data from all participants will be shared.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 8, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07270965
Lead sponsor
University of British Columbia
Collaborators
L'Oreal
Responsible party
Wingfield Rehmus (Principal Investigator, University of British Columbia) — Principal investigator
First posted
Dec 8, 2025
Start date
Dec 2025 (estimated)
Primary completion
Dec 2026 (estimated)
Completion
Dec 2026 (estimated)
Last update
Dec 8, 2025

Study contacts

Wingfield Rehmus, MD, MPH
Contact
dermatologyresearch@cw.bc.ca
1-604-875-2606

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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