A Phase 1 interventional study of compare different types of biomaterials 4 months after application through the use of ASP compare different types of biomaterials 4 months after application through the use of ASP Group 2 and Comparison of different types of biomaterials 4 months after application through the use of ASP in Extracting Own Teeth, sponsored by University of Foggia. Active, not recruiting at 1 site in Italy. Open to participants aged 18 Years to 90 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-30.
Sponsored by University of Foggia · Phase 1, Interventional, and Prevention
The maxillary bone atrophies from traumatic, pathological events or related to physiological bone loss after tooth extraction, promoting a decrease in bone volume (vertical-horizontal) which has always been a crucial challenge for the clinician in order to obtain adequate rehabilitations prosthetics.
The results of bone loss induced aesthetic and functional difficulties in achieving surgical and prosthetic rehabilitation of the right dental implant.
Bone loss can be restored with autologous bone grafts and in large bone atrophy of the jaws require complex surgical techniques such as vascularized bone transplantation.
As an alternative to the reconstruction of the maxillary tissue, several surgical techniques have been promoted to prevent or minimize bone resorption through market biomaterials with or without the patient's autologous bone.
To reduce or counteract biological bone resorption, surgeons have promoted alveolar cavity preservation procedures (ASP) with autologous or heterologous graft materials.
Recently, several studies have been published to evaluate the use of demineralized dentin material derived from the extracted tooth to obtain new bone in the maxillary post-extraction site.
The aim of the study is to compare different types of biomaterials 4 months after application through the use of the alveolar socket preservation technique.
Exclusion Criteria:
Procedure: compare different types of biomaterials 4 months after application through the use of ASP compare different types of biomaterials 4 months after application through the use of ASP Group 2
Procedure: Comparison of different types of biomaterials 4 months after application through the use of ASP
Biological: Comparison different types of biomaterials 4 months after application through the use of ASP
Procedure: The aim is to compare different types of biomaterials 4 months after application through the use of ASP
Procedure: The aim is to compare different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 1
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 2
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 3
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 4
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 5
Comparison of different biomaterials at 4 months to assess the percentage of residual biomaterial remaining in situ and the percentage of newly formed bone in the regenerated area.
Time frame: 4 months after surgery
Plan to share: Undecided
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This study is active, not recruiting, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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University of Foggia