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Not yet recruitingNCT07266220DiCKD-CAROTIDUpdated Dec 5, 2025

Carotid Doppler Screening for Subclinical Atherosclerosis in Diabetic CKD Patients.

An observational study in Diabetes Mellitus, Type 2, Chronic Kidney Disease and Atherosclerosis, sponsored by Abdallah Ali Mohammed. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-12-05.

Sponsored by Abdallah Ali Mohammed · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
96
Ages
18 Years and older
Sex
All
01

Study summary

This study is being done at Assiut University to look for early signs of hardening of the arteries (atherosclerosis) in people who have both diabetes and chronic kidney disease (CKD). Many patients with these conditions are at higher risk of heart disease and stroke, but the disease can develop quietly without symptoms.

We will use a safe, non-invasive test called carotid Doppler ultrasound, which uses sound waves to check the neck arteries (carotid arteries) for early changes. The goal is to see how often these early changes occur in patients with diabetes and CKD, and whether the findings relate to their kidney function, blood sugar control, and other health factors.

This research may help doctors detect vascular problems earlier and guide better prevention strategies for patients at risk.

02

Conditions studied

  • Diabetes Mellitus, Type 2
  • Chronic Kidney Disease
  • Atherosclerosis
03

In context

Diabetes Mellitus, Type 2

9,359 studies on the registry are indexed under Diabetes Mellitus, Type 2; 1,318 are open to participants now.

This study's planned enrollment of 96 is below the median of 300 across 1,588 observational studies indexed under Diabetes Mellitus, Type 2.

Browse Diabetes Mellitus, Type 2 studies →

Lead sponsor

This is the only study on the registry with Abdallah Ali Mohammed as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients with type 2 diabetes mellitus and stage 3 chronic kidney disease recruited from the nephrology and internal medicine outpatient clinics and inpatient wards of Assiut University Hospitals.

Eligibility criteria

  1. Age≥18years.
  2. Diagnosis of type 2 diabetes mellitus (per treating physician or ADA criteria).
  3. CKDstage3:eGFR30-59mL/min/1.73 m² on at least two measurements ≥3 months apart OR established diagnosis in medical record.
  4. Clinically stable (no AKI, no hospitalization for cardiovascular event in past 3 months).
  5. Ableandwilling to provide informed consent.
05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
96 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Prevalence of subclinical carotid atherosclerosis (defined as increased carotid intima-media thickness and/or carotid plaque detected by carotid Doppler ultrasound).

    Carotid Doppler ultrasound will be performed once at study entry to measure carotid intima-media thickness and detect the presence of carotid plaque. The percentage of patients with subclinical carotid atherosclerosis will be estimated among adults with type 2 diabetes mellitus and stage 3 chronic kidney disease.

    Time frame: At baseline (single assessment at enrollment).

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 5, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07266220
Lead sponsor
Abdallah Ali Mohammed
Responsible party
Abdallah Ali Mohammed (Resident Physician, Internal Medicine, Assiut University) — Sponsor-investigator
First posted
Dec 5, 2025
Start date
Jan 2026 (estimated)
Primary completion
Mar 2027 (estimated)
Completion
Apr 2027 (estimated)
Last update
Dec 5, 2025

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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