An observational study in Cerebral Palsy, sponsored by IRCCS Eugenio Medea. Completed at 1 site in Italy. Open to participants aged 7 Years to 18 Years. Per ClinicalTrials.gov, last updated 2025-11-21.
Sponsored by IRCCS Eugenio Medea · Observational
The WittyChildren project aims to evaluate the response to visual stimuli in terms of reaction times and movement execution using advanced instruments. The evaluation is aimed at children with motor and cognitive deficits associated with various pathologies such as Down Syndrome, Infantile Cerebral Palsy, Autism. The evaluation protocol involves the execution of specific memory tasks: the child is asked to turn off light targets equipped with proximity sensors by approaching their hand. These visual signals, consisting of colored lights and symbols, are emitted according to pre-established patterns by a dedicated LED system (WittySEM - Microgate) capable of precisely measuring reaction times. During the execution of the task, quantitative and multifactorial analysis of movement and posture is also performed using an optoelectronic system (Smart DX - BTS Bioengineering) in order to obtain a complete analysis obtained from the combination of information regarding the child's motor and cognitive abilities. The analysis is repeated pre- and post-specific rehabilitation treatment, such as ARMEO, CIMT and occupational therapy, with the aim of evaluating the effects with objective and quantitative measurements through cutting-edge instruments, thus overcoming the intrinsic limits of commonly used scales and clinical tests. The project will be implemented in collaboration with the Politecnico di Milano - Lecco Territorial Campus and the IRCCS Eugenio Medea - Associazione la nostra famiglia. The first will provide the study with the necessary equipment at the "Human Performance Laboratory - E4Sport" of the Lecco Territorial Campus and the biomechanical engineering skills. The second, thanks to its consolidated experience in the treatment, rehabilitation and research of childhood pathologies, will provide the necessary support from a medical/rehabilitative point of view.
1,852 studies on the registry are indexed under Cerebral Palsy; 437 are open to participants now.
This study's enrollment of 20 is below the median of 63 across 454 observational studies indexed under Cerebral Palsy.
Browse Cerebral Palsy studies →IRCCS Eugenio Medea is the lead sponsor of 104 studies on the registry; 52 are open to participants now.
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Patients affected by unilateral cerebral palsy
Exclusion Criteria:
The possibility of using tools for objective and quantitative evaluations can overcome these limitations. Added to this is the need to evaluate the beneficial effects of rehabilitation so as to understand its effectiveness and impact on quality of life. However, it is difficult to resort to tests that use dedicated devices such as the WittySEM system which, in addition to simultaneously allowing the evaluation of the movement associated with the execution of the task, also provides for an active and "play-like" involvement of the subject which should not be underestimated in the case of children.
Reaction time - before rehabilitation
Reaction time as measured through optoelectronic data.
Time frame: Baseline, before starting rehabilitation treatment
Reaction time - after rehabilitation
Reaction time as measured through optoelectronic data.
Time frame: After one month
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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IRCCS Eugenio Medea