ClinicalTrials.gg
RecruitingNCT07230951Updated Nov 17, 2025

Interaction Between White Potato Consumption and Meal Timing on Glycemic Response and Appetite in Adults

An interventional study of Oven-baked Home Fries and Oven-baked White Russet Potato in Healthy, Adult and Appetite, sponsored by Toronto Metropolitan University. Recruiting at 1 site in Canada. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-11-17.

Sponsored by Toronto Metropolitan University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Started Oct 2025; still recruiting 1 year later.
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The purpose of this study is to evaluate the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. The investigators hypothesize that white potatoes will modulate glycemic response, enhance satiety, and mitigate subsequent meal consumption and overall food intake when compared with meals containing low glycemic carbohydrates. Furthermore, they anticipate that the timing of white potato consumption will yield differential effects, with breakfast consumption exerting a more pronounced impact on satiety and subsequent food intake reduction compared to dinner consumption.

Read the detailed description

A randomized within-subject repeated measures experiment will be used to study the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. In Experiment 1, participants will consume, in a random order on separate mornings, one of six test meals consisting of an egg omelette and a test side of: (1) Oven-baked home fries, (2) Oven-baked white russet potatoes, (3) Deep-fried, quick serve fries, (4) Oven-baked fries, (5) Oven-baked cauliflower tots, or (6) no side. Acute glycemic response and subjective appetite will be measured at baseline and over 120-mins post treatment consumption. At 120-min, food intake will be evaluated via an ad libitum lunch. Rest of day food intake and glycemic response will be collected until the participant goes to bed. Blood glucose measurements will be collected using the Dexcom G7 continuous glucose monitoring system.

02

Conditions studied

  • Healthy
  • Adult
  • Appetite
  • Glycemic Response
  • Mealtiming
03

In context

Lead sponsor

Toronto Metropolitan University is the lead sponsor of 63 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 18 - 65 years
  • within the healthy body weight range [ (BMI) between 18.5 - 24.9 kg/m2].

Exclusion criteria

Exclusion Criteria:

  • have a previous diagnosis of diabetes and gastrointestinal, liver or kidney disease;
  • have had a major medical or surgical event within the past 6 months;
  • have had any significant weight fluctuation in the past 6-months;
  • are taking medication that may influence dependent measures;
  • are or have been on a diet within the past 6 months;
  • skip breakfast or are unable to consume test treatment food.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Oven-baked Home Fries

    Test Treatment

    Other: Oven-baked Home Fries

  • Experimental
    Oven-baked White Russet Potato

    Test Treatment

    Other: Oven-baked White Russet Potato

  • Experimental
    Oven-baked Fries

    Test Treatment

    Other: Oven-baked Fries

  • Experimental
    Deep Fried, Quick Serve Fries

    Test Treatment

    Other: Deep Fried, Quick Serve Fries

  • Experimental
    Oven-baked Cauliflower Veggie Tots

    Test Treatment

    Other: Oven-baked Cauliflower Veggie Tots

  • Experimental
    No Side

    Test Treatment

    Other: No Side

Interventions

  • OtherOven-baked Home Fries

    Oven-baked Home Fries (241 g; McCain Ltd.). Test treatments matched for calories (284 kcal)

  • OtherOven-baked White Russet Potato

    Oven-baked White Russet Potato (299 g). Test treatments matched for calories (284 kcal)

  • OtherOven-baked Fries

    Oven-baked Fries (201 g; McCain Ltd.). Test treatments matched for calories (284 kcal)

  • OtherDeep Fried, Quick Serve Fries

    Deep Fried, Quick Serve Fries (108 g; McCain Ltd.). Test treatments matched for calories (284 kcal)

  • OtherOven-baked Cauliflower Veggie Tots

    Oven-baked Cauliflower Veggie Tots (186 g; Green Giant). Test treatments matched for calories (284 kcal)

  • OtherNo Side

    No side control (no caloric contribution).

06

What researchers measure

Primary outcomes

  1. Glycemic Response (Acute Phase)

    Blood glucose (mmol/L). Blood glucose concentrations will be measured using a Dexcom G7 CGM system.

    Time frame: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).

  2. Rest-of-day Blood Glucose

    Blood glucose (mmol/L). Rest-of-day blood glucose concentrations will be determined using a Dexcom G7 CGM system.

    Time frame: Continuous measurements for 24 hours post-treatment consumption.

  3. Ad Libitum Food Intake

    Lunch pizza meal. Food intake will be determined by weighing the meal before and after serving. The net weight of the test meal will be converted to calories.

    Time frame: At 120 minutes post-treatment consumption

Secondary outcomes

  1. Subjective Appetite

    A visual analogue scale (VAS) with four questions will be administered to assess desire to eat, fullness, hunger, and prospective food consumption. Individual questions will be used to form a composite score. Each VAS will be administered via a digital software application (Express VAS, Toronto, Ontario, Canada) on a Dell tablet where participants will place an 'X" on the VAS line (100 unit scale).

    Time frame: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).

  2. Rest-of-day Food Intake

    Participants will be sent home with a rest-of-the-day food intake recall sheet to record their snacks, meals, and beverages. Rest of day food log.

    Time frame: For the rest of the day following test session completion (1 day)

  3. Subjective Emotions

    A visual analogue scale (VAS) with thirteen questions will be administered to assess subjective emotions and mood (aggression, anger, excitement, disappointment, happiness, upset, frustration, alertness, sadness, tension, exhaustion, calmness, and sleepiness). Individual questions will be used to form a composite emotion score. Each VAS will be administered via a digital software application (Express VAS, Toronto, Ontario, Canada) on a Dell tablet where participants will place an 'X" on the VAS line (100 unit scale).

    Time frame: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).

07

Study locations

1 of 1 sites recruiting
  • Centre for Urban Innovation (CUI-109), School of Nutrition, Toronto Metropolitan University
    Toronto, Ontario M5B2K3, Canada
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 17, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07230951
Lead sponsor
Toronto Metropolitan University
Collaborators
Alliance for Potato Research and Education
Responsible party
Nick Bellissimo, PhD (Professor, Toronto Metropolitan University) — Principal investigator
First posted
Nov 17, 2025
Start date
Oct 30, 2025
Primary completion
Oct 2027 (estimated)
Completion
Oct 2027 (estimated)
Last update
Nov 17, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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