An interventional study of Yoga and meditation and Wellness in Posttraumatic Stress Disorder (PTSD), sponsored by Veterans Medical Research Foundation. Recruiting at 5 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-23.
Sponsored by Veterans Medical Research Foundation · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to determine whether which types of integrative care, meaning a combination of psychotherapy and mind-body interventions, lead to the most changes in functioning among Veterans with posttraumatic stress disorder (PTSD). The main aims are:
Participants will:
2,682 studies on the registry are indexed under Stress Disorders, Post-Traumatic; 601 are open to participants now.
This study's planned enrollment of 300 is above the median of 69 across 2,196 interventional studies indexed under Stress Disorders, Post-Traumatic.
Browse Stress Disorders, Post-Traumatic studies →Veterans Medical Research Foundation is the lead sponsor of 43 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Information about local and national complementary and integrative health programs
Other: Information
Hatha yoga classes via videoconferencing and self-learning of Mantram Repetition Program
Behavioral: Yoga and meditation · Other: Information
Weekly exercise/nutrition classes to support lifestyle changes
Behavioral: Wellness · Other: Information
Weekly classes focused on increasing positive affect and social support
Behavioral: Positive affect · Other: Information
12 weekly 60-minute hatha yoga classes and access to video-based training in a portable mantra-based meditation practice
12 weekly 60-minute classes to provide education about exercise and nutrition and facilitate lifestyle changes
12 weekly 60-minute classes to teach strategies for increasing positive affect and to provide social connection
Provision of written information about local and national complementary and integrative care resources
Inventory of Psychosocial Functioning (IPF)
The IPF is a self-report measure of functioning across several domains. It is summarized in a mean score with higher scores indicating greater functional impairment.
Time frame: weeks 0, 12 and 24
Clinician Administered PTSD Scale for DSM-5 Revised (CAPS-5R)
The CAPS-5R is a clinician-administered measure of PTSD symptom severity summarized in a total score with higher scores indicating greater symptom severity.
Time frame: weeks 0, 12 and 24
Quick Inventory of Depressive Symptomatology (QIDS)
The QIDS is a self-report measure of depression severity summarized by a total score for which higher scores reflect greater symptom severity.
Time frame: weeks 0, 12 and 24
Insomnia Severity Index (ISI)
The ISI is a self-report measure that assesses the consequences of and distress related to insomnia summarized by a total score in which higher scores indicate greater sleep disruption.
Time frame: weeks 0, 12 and 24
Plan to share: Yes — Deidentified datasets will be made available via National Institutes of Mental Health Data Archive (NDA). The study protocol, statistical analysis plan and ICF/HIPAA form will be available on clinical.trials.gov.
Supporting information: Study protocol, Statistical analysis plan, Informed consent form
Time frame: Data and supporting information will be available within 1 year of the conclusion of the trial and archived according to the standards of the hosting archives.
Access criteria: Unique research resources will be readily available for research purposes to members of academic institutions, non-profit organizations, and commercial partners after the completion of data analysis, presentations, and publications
Data sharing details ↗ · nda.nih.gov
No publications or documents are linked to this record.
Started Apr 2026 (actual). Primary completion is estimated for Jun 2029, 38 months after the start.
Of 1,064 non-industry interventional studies with no phase under Stress Disorders, Post-Traumatic, half reached primary completion within 35 months of starting (the median), counting those still running; a quarter within 17 and three quarters within 53. This study's planned 38 months is close to that.
Counting every sponsor, half of 1,092 studies reached it within 34 months; a quarter within 17 and three quarters within 53.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Stress Disorders, Post-Traumatic →
Veterans Medical Research Foundation