An interventional study of Time Restricted Eating and Group education in Diet Habits and Cancer Prevention, sponsored by University of Oklahoma. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-06.
Sponsored by University of Oklahoma · Not applicable, Interventional, and Prevention
This study is seeking to examine combinations of two different dietary interventions on cancer risk.
333 studies on the registry are indexed under Intermittent Fasting; 99 are open to participants now.
This study's planned enrollment of 90 is above the median of 50 across 320 interventional studies indexed under Intermittent Fasting.
Browse Intermittent Fasting studies →University of Oklahoma is the lead sponsor of 432 studies on the registry; 100 are open to participants now.
Of its 42 completed or terminated interventional studies of FDA-regulated products, 16 (38%) have results posted.
Compared within Intermittent Fasting, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Feeding Behavior. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Behavioral: Group education · Behavioral: Counseling
Behavioral: Time Restricted Eating
Behavioral: Time Restricted Eating · Behavioral: Group education · Behavioral: Counseling
10-hour Time Restricted Eating (TRE)
Group education about dietary fiber
Counseling and motivational interviewing to promote uptake of diet changes
Dietary fiber intake
Dietary fiber intake as reported on 3-day diet records and analyzed according to Nutrition Data System for Research; reported as a mean intake over three days in grams per day
Time frame: Baseline, post-intervention (approximately 3 months), and post-observation (approximately 12 months)
Body mass/weight
Body mass/weight will be measured in kilograms
Time frame: Baseline, post-intervention (approximately 3 months), and post-observation (approximately 12 months)
Blood pressure
Blood pressure (systolic and diastolic) will be measured at each time frame (in millimeters of mercury \[mmHg\])
Time frame: Baseline, post-intervention (approximately 3 months), and post-observation (approximately 12 months)
Blood-based measures of inflammation
Venous blood samples will be collected and analyzed for inflammatory markers: Granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon-gamma (IFN-γ), interleukin-1 beta (IL-1β), interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-5 (IL-5), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), and tumor necrosis factor-alpha (TNF-α).
Time frame: Baseline, post-intervention (approximately 3 months), and post-observation (approximately 12 months)
Blood-based measures of oxidative stress
Venous blood samples will be collected and analyzed for measures of oxidative stress, including reactive oxygen species and lipid peroxidation
Time frame: Baseline, post-intervention (approximately 3 months), and post-observation (approximately 12 months)
Blood-based measures of insulin resistance
Insulin resistance will be measured via assessment of insulin and glucose in venous blood samples, and used to assess Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)
Time frame: Baseline, post-intervention (approximately 3 months), and post-observation (approximately 12 months)
Affect
Self-reported affect will be assessed using ecological momentary assessment, delivered via cell phone
Time frame: Daily for three months
Sleep
Sleep will be measured via Fitbits, assessed as mean minutes/night
Time frame: Daily for three months
Physical Activity
Physical activity will be measured via Fitbits, assessed as mean steps/day
Time frame: Daily for three months
Plan to share: No
No publications or documents are linked to this record.
Started Dec 2025 (actual). Primary completion is estimated for Jun 2027, 18 months after the start.
Of 257 non-industry interventional studies with no phase under Intermittent Fasting, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 34. This study's planned 18 months is close to that.
Counting every sponsor, half of 263 studies reached it within 17 months; a quarter within 8 and three quarters within 34.
How these figures are worked out, and which studies are left out of them.
This study is active, not recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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