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Not yet recruitingNCT07218614Updated Oct 20, 2025

Can Mobilizations Applied to the Thoracic Spine Improve Oxygen Saturation Levels and Thoracic Kyphosis in E-Cigarette Smokers?

An interventional study of Thoracic Mobilization and Light Touch Contact in Thoracic Kyphosis, sponsored by New York Institute of Technology. Not yet recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-10-20.

Sponsored by New York Institute of Technology · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Apr 2026, 7 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this study is to determine if manual therapy can improve thoracic spinal posture and pulse oximetery in individuals who use e-cigarettes.

The main questions the study aims to answer are:

  • Is there an immediate improvements in thoracic posture
  • Is there immediate improvements in pulse oximetery Research will compare an experimental group and a control group to examine the effects.
Read the detailed description

All participants will be recruited from flyers posted throughout the NYIT Long Island campus. The participants will be screened for inclusion using set criteria by the PI.

In this crossover design study, participants will be randomly assigned to either an intervention experimental group or sham control group. The intervention group will received a thoracic extension mobilization to the mid-thoracic spine for a duration of 60 seconds and this will be repeated for a total of three times. The sham group will received a light, non-therapeutic touch to both scapulae which will be applied for three minutes. Both interventions will be performed in a seated position. Measurements of thoracic kyphosis and oxygen saturation will be taken before and after each procedure using inclinometers and a pulse oximeter, respectively.

After a washout period of one week, the participants will be return and receive the other form of intervention that they did no receive in in the first week. All procedures and outcomes will be performed as noted above.

02

Conditions studied

  • Thoracic Kyphosis

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Keywords

  • Thoracic spine, pulse oximetery, mobilzation
03

In context

Kyphosis

132 studies on the registry are indexed under Kyphosis; 31 are open to participants now.

This study's planned enrollment of 20 is below the median of 44 across 82 interventional studies indexed under Kyphosis.

Browse Kyphosis studies →

Lead sponsor

New York Institute of Technology is the lead sponsor of 59 studies on the registry; 15 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Current e-cigarette user Accentuated thoracic kyphosis (Cobb angle >20 degrees) Age range: at least 18 years old Good overall health

Exclusion criteria

Exclusion Criteria:

History of respiratory disease Recent vertebral fractures Recent spinal surgery Vertebral instability Congenital or acquired thoracic cage deformities Prolonged use Osteoporosis/osteoporosis Inability to provide

Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
20 participants (estimated)

Study arms

  • Experimental
    Thoracic Mobilization

    The intervention group will receive a posterior to anterior directed thoracic mobilization to the mid-thoracic spine to facilitate extension. This will be imparted for a duration of 60 seconds, and this will be repeated for a total of three times. Interventions will be performed in a seated position.

    Other: Thoracic Mobilization

  • Sham comparator
    Light Touch Contact

    The sham treatment will be applied to each subject. The sham treatment of light, non-therapeutic touch will be applied to both scapulae for three minutes. Interventions will be performed in a seated position.

    Other: Light Touch Contact

Interventions

  • OtherThoracic Mobilization

    The intervention group will receive a posterior to anterior directed thoracic mobilization to the mid-thoracic spine to facilitate extension. This will be imparted for a duration of 60 seconds, and this will be repeated for a total of three times. Interventions will be performed in a seated position.

  • OtherLight Touch Contact

    The sham treatment will be applied to each subject. The sham treatment of light, non-therapeutic touch will be applied to both scapulae for three minutes. Interventions will be performed in a seated position.

06

What researchers measure

Primary outcomes

  1. Angle of Thoracic Kyphosis

    Measurement of the thoracic kyphosis will be made both pre and post treatment using excepted normative values (Cobb angle)

    Time frame: Immediately before and after each intervention

Secondary outcomes

  1. Oxygen Saturation

    Percentage of oxygen found in the peripheral circulation using a pulse oximeter

    Time frame: immediately before and after intervention

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No — There is no plan to share IPD for this study.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 20, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07218614
Lead sponsor
New York Institute of Technology
Responsible party
Sponsor
First posted
Oct 20, 2025
Start date
Oct 15, 2025 (estimated)
Primary completion
Apr 1, 2026 (estimated)
Completion
May 15, 2026 (estimated)
Last update
Oct 20, 2025

Study contacts

Teresa M Ingenito, DPT
Contact
tingenit@nyit.edu
516-635-3974
Mark J Gugliotti, DPT
Contact
mgugliot@nyit.edu
631-512-5559
Teresa M Ingenito, DPT
principal investigator · New York Institute of Technology

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.

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