ClinicalTrials.gg
RecruitingNCT07209072Updated Jan 28, 2026

Emergency Department Linkage to Care for Patients Experiencing Homelessness

An interventional study of Street medicine follow up in Homelessness, sponsored by Denver Health and Hospital Authority. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-01-28.

Primary conditionnone(registry's first term: Emergencies)No conditionIs this wrong?Emergencies describes something many studies share rather than a condition a study is about. The study names no condition we can place it under, so it is not compared with other studies by condition.

Sponsored by Denver Health and Hospital Authority · Not applicable, Interventional, and Health services research

From the registry’s dates

  • Started Dec 2025; still recruiting 11 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
390
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
01

Study summary

In an effort to improve access to primary care at time of discharge, patients who are homeless will be given either enhanced follow up through a street medicine team or routine follow up in clinic.

Read the detailed description

Patients who experience homelessness frequently utilize the ED, but lack follow up primary care. In an effort to augment access to post-ED primary care, the investigators propose a quasi-experimental equivalent time sample study in which patients fitting certain diagnostic and inclusion criteria are allocated to either a) a referral to the Comprehensive Care Clinic at Denver Health, or b) a referral to Colorado Coalition for the Homeless (CCH) Stout Street medicine clinic. The street medicine clinic aims to lower barriers to access by locating patients on the street and providing primary care rather than asking patients to present to clinic. All patients will still receive the hospital appointment line number at time of discharge. 1 month and 3 months after index visit, the investigators will examine follow up rates at both clinics as well as secondary outcomes including ED visits, hospitalizations, and mortality through chart review of Denver Health and CCH electronic health records and CORHIO.

02

Conditions studied

  • Homelessness

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Keywords

  • primary care
  • emergency department
  • homelessness
03

In context

Lead sponsor

Denver Health and Hospital Authority is the lead sponsor of 84 studies on the registry; 4 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 8 (89%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. adult (≥18 years of age) DHMC ED patient,
  2. currently unsheltered, defined as living on the streets, in a vehicle, or in another place not fit for human habitation,
  3. anticipating ED discharge, with
  4. a diagnosis listed below that requires short-term follow up:

    • or asthma exacerbation
    • Bacterial or viral pneumonia
    • CHF with volume overload
    • SSTI
    • Dehydration requiring IV fluids
    • Hyperglycemia secondary to DM
    • Frostbite
    • First- and second-degree burns
    • Bacterial ENT infections
    • Diabetic foot infection
    • Traumatic head injury
    • Pregnancy
    • Opioid overdose
  5. a stable location (i.e., an intersection, landmark, or encampment where they can be located by the street medicine team) within Denver County for at least 2 weeks.

Exclusion criteria

Exclusion Criteria:

  1. have altered mentation (e.g., intoxication, or secondary to medical, psychiatric, or behavioral conditions) that are unable to communicate their location, contact information, or agree to follow up.
  2. are prisoners,
  3. previously enrolled.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

COPD

Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.

05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
390 participants (estimated)

Study arms

  • No intervention
    Standard of Care

    Patients will receive a referral to a rapid follow up clinic at time of discharge

  • Experimental
    Street medicine

    Patients will receive a referral to street medicine at time of discharge

    Behavioral: Street medicine follow up

Interventions

  • BehavioralStreet medicine follow up

    This intervention will use electronic health record builds to automatically send a referral to a street medicine clinic, who will attempt to contact the patient within 2 weeks.

06

What researchers measure

Primary outcomes

  1. ED visits

    Repeat visits to the ED

    Time frame: 1 and 3 months

Secondary outcomes

  1. Inpatient hospitalizations

    Inpatient hospitalizations at this same hospital

    Time frame: 1 and 3 months

  2. Mortality

    Death

    Time frame: 3 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: No — At this time there is no plan to share IPD. Sharing of data will be considered on a case by case basis and only de-identified data will be shared.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 28, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07209072
Lead sponsor
Denver Health and Hospital Authority
Responsible party
KJoseph (Principal Investigator, Denver Health and Hospital Authority) — Principal investigator
First posted
Oct 6, 2025
Start date
Dec 5, 2025
Primary completion
Jun 2027 (estimated)
Completion
Dec 2027 (estimated)
Last update
Jan 28, 2026

Study contacts

Kathleen M Joseph, MD MPH
Contact
kathleen.joseph@dhha.org
13175194468
Carolynn Lyle, PAC MPH
Contact
carol.lyle@dhha.org
Jason Haukoos, MD MSc
study director · Denver Health Medical Center

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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