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CompletedNCT07202286PARTICIPATEUpdated Oct 6, 2025

Comparing Physician and Artificial Intelligence Chatbot Responses to Frequently Asked Questions From Osteoarthritis Patients

An observational study in Osteo Arthritis Knee and Hip, Artificial Intelligence (AI) and Acceptability, sponsored by Canisius-Wilhelmina Hospital. Completed at 1 site in Netherlands. Per ClinicalTrials.gov, last updated 2025-10-06.

Sponsored by Canisius-Wilhelmina Hospital · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
286
Sex
All
01

Study summary

This study aimed to compare the patient acceptability (preference, length, and difficulty) and accuracy of Chat-Generative Pre-Trained Transformer (ChatGPT) responses to questions from people with osteoarthritis (OA) with physician responses.

Read the detailed description

This was a cross-sectional study where participants were invited by e-mail to participate in the questionnaire to compare Chatbot responses to physician responses.

02

Conditions studied

  • Osteo Arthritis Knee and Hip
  • Artificial Intelligence (AI)
  • Acceptability
  • Accuracy
  • Chatbot

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Keywords

  • chatGPT
  • Osteoarthritis
  • Acceptability
  • Accuracy
  • Artificial Intelligence
  • Cross-sectional
03

In context

Osteoarthritis

2,974 studies on the registry are indexed under Osteoarthritis; 438 are open to participants now.

This study's enrollment of 286 is above the median of 100 across 601 observational studies indexed under Osteoarthritis.

Browse Osteoarthritis studies →

Lead sponsor

Canisius-Wilhelmina Hospital is the lead sponsor of 11 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

There were two groups of participants: 1) a panel of people with OA evaluating the preference, length, and difficulty, and 2) a panel of experts in the field of OA evaluating the accuracy of the responses

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • all individuals visiting the Department of Orthopedics in the Canisius Wilhelmina Hospital, a district general hospital in Nijmegen, The Netherlands, diagnosed with knee or hip OA between March 2023 and March 2024

Exclusion criteria

Exclusion Criteria:

  • partly completion of the questionnaire
05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
286 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Preferred response

    Binary outcome, chatbot or physician response. This was an average based on the preferences on the 7 FAQs.

    Time frame: From invitation until the end of the study at two weeks

Secondary outcomes

  1. Rating of length

    Rating of both responses (chatbot and physician response) included 'too short', 'good', and 'too long'.

    Time frame: From invitation until the end of the study at two weeks

  2. Rating of difficulty

    Rating of difficulty included 'too easy', 'good', and 'too difficult' for both responses.

    Time frame: From invitation until the end of the study at two weeks

  3. Accuracy

    Accuracy of the responses included the options 'Completely incorrect,' 'partly incorrect, ' 'approximately equally correct and incorrect,' 'mostly correct,' 'completely correct'.

    Time frame: From invitation until the end of the study at two weeks

Other outcomes

  1. Number of words of the responses

    Time frame: This was determined before the study started

07

Study locations

1 site
  • Canisius Wilhelmina Hospital
    Nijmegen, Netherlands
08

References and documents

Individual participant data

Plan to share: Undecided — The dataset supporting the conclusions of this study is available from the corresponding author upon reasonable request.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 6, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07202286
Lead sponsor
Canisius-Wilhelmina Hospital
Responsible party
Sponsor
First posted
Oct 1, 2025
Start date
May 22, 2024
Primary completion
Jun 5, 2024
Completion
Jun 5, 2024
Last update
Oct 6, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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